Protaminization of somatic cells nuclei as a model for nuclear reprogramming in somatic cell nuclear transfer.
2019/35/B/NZ3/02856
Keywords
Descriptors
- NZ3_013: Biologia rozwoju zwierząt
Panel
NZ3 – Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology
Host institution
Instytut Genetyki i Hodowli Zwierząt PAN
Voivodeship: mazowieckie
Principal investigator (from the host institution)
Number of co-investigators in the project: 4
Call
OPUS 18 – announced on 2019-09-16
- Amount awarded
- 1 738 800 PLN
- Project start date
- 2020-07-28
- Project end date
- 2025-07-27
- Project duration
- 60 months (the same as in the proposal)
- Project status
- Project completed
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
Publication in academic press/journals (9)
-
Omne vivum ex ovo: the oocyte reprogramming and remodeling activities.
- Authors:
- Helena Fulka, Pasqualino Loi, Marta Czernik, Azim Surani, Josef Fulka
- Academic press:
- Reproduction (year: 2023, volume: 165(3),, pages: pp. R75–R89), Publisher: Bioscientifica; BIOSCIENTIFICA LTD.; SOCIETY FOR REPRODUCTION AND FERTILITY
- Status:
- Published
- DOI:
- 10.1530/REP-22-0124 – link to the publication
-
Oocyte activation is a cytoplasm-confined event so far: what about the nucleus?
- Authors:
- Luisa Gioia, Luca Palazzese, Marta Czernik, Domenico Iuso, Helena Fulka, Josef Fulka Jr, and Pasqualino Loi
- Academic press:
- Reproduction (year: 2024, volume: 2024 Mar 1;, pages: 167(3): e230360), Publisher: Bioscientifica; BIOSCIENTIFICA LTD.; SOCIETY FOR REPRODUCTION AND FERTILITY
- Status:
- Published
- DOI:
- 10.1530/REP-23-0360 – link to the publication
-
Reviving vacuum-dried encapsulated ram spermatozoa via ICSI after 2 years of storage
- Authors:
- Luca Palazzese, Federica Turri, Debora Agata Anzalone, Joseph Saragusty, Jacques Bonnet, Marthe Colotte, Sophie Tuffet, Flavia Pizzi, Alessia Luciani, Kazutsugu Matsukawa, Marta Czernik, Pasqualino Loi
- Academic press:
- Frontiers in Veterinary Science (year: 2023, volume: 10, pages: 1270266), Publisher: Frontiers
- Status:
- Published
- DOI:
- 10.3389/fvets.2023.1270266 – link to the publication
-
25th ANNIVERSARY OF CLONING BY SOMATIC-CELL NUCLEAR TRANSFER: Scientific and technological approaches to improve SCNT efficiency in farm animals and pets
- Authors:
- Loi P., Palazzese L., Scapolo P.A., Fulka J., Fulka H., Czernik M
- Academic press:
- Reproduction (year: 2021, volume: 162, pages: 33-43), Publisher: Society for Reproduction and Fertility
- Status:
- Published
- DOI:
- 10.1530/REP-20-0653 – link to the publication
-
Controlled spermatozoa-oocyte interaction improves embryo quality in sheep
- Authors:
- Anzalone D.A., Palazzese L., Czernik M., Sabatucci A., Valbonetti L., Capra E., Loi P
- Academic press:
- Scientific Reports (year: 2021, volume: 11, pages: 22692), Publisher: Nature
- Status:
- Published
- DOI:
- 10.1038/s41598-021-02000-z – link to the publication
-
Advances in induced anhydrobiosis for cell and gamete storage.
- Authors:
- Loi P, Palazzese L, Moncada M, Sterzo ML, Iuso D, Czernik M, Wakayama T, Kikawada T.
- Academic press:
- Trends Biotechnol (year: 2025, volume: 5:S0167-7799(25)00047-2, pages: 00047-2), Publisher: Cell Press
- Status:
- Published
- DOI:
- 10.1016/j.tibtech.2025.02.010 – link to the publication
-
Nucleus reprogramming/remodeling through selective enucleation (SE) of immature oocytes and zygotes: a nucleolus point of view
- Authors:
- Helena Fulka, Pasqualino Loi, Luca Palazzese, Michal Benc, Josef Fulka Jr Jr
- Academic press:
- The Journal of Reproduction and Development. (year: 2022, volume: 1;68(3):, pages: 165-172), Publisher: Society for Reproduction and Development
- Status:
- Published
- DOI:
- 10.1262/jrd.2022-004 – link to the publication
-
Exogenous LEA proteins expression enhances cold tolerance in mammalian cells by reducing oxidative stress
- Authors:
- Lo Sterzo M, Iuso D, Palazzese L, Moncada M, Boffa F, Scudieri A, Gioia L, Czernik M, Loi P.
- Academic press:
- Scientific Reports (year: 2025, volume: 15, pages: 3351), Publisher: Springer Nature
- Status:
- Published
- DOI:
- 10.1038/s41598-025-86499-6 – link to the publication
-
Mitochondrial function and intracellular distribution is severely affected in in vitro cultured mouse embryos
- Authors:
- Marta Czernik, Dawid Winiarczyk, Silvestre Sampino , Paweł Gręda , Salvatore Parillo, Jacek Andrzej Modliński, Pasqualino Loi
- Academic press:
- Scientific Reports (year: 2022, volume: 27;12(1), pages: 16152), Publisher: Nature Publishing Groupe
- Status:
- Published
- DOI:
- 10.1038/s41598-022-20374-6 – link to the publication
Book publications / chapters in book publications (1)
-
Somatic Cell Nuclear Transfer Using Freeze-Dried Protaminized Donor Nuclei
- Authors:
- Luca Palazzese, Marta Czernik, Kazutsugu Matsukawa, Pasqualino Loi
- Book:
- Somatic Cell Nuclear Transfer Technology (year: 2023, volume: 2647, pages: pp 211–224), Publisher: Humana Press
- Status:
- Published