Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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The role of epidermal protein Regnase-1 in chronic itch-associated diseases.

2019/35/B/NZ6/03357

Keywords:

Skin cutaneous immune and nervous system itch chronic idiopatic pruritus atopic dermatitis.

Descriptors:

  • NZ6_001:
  • NZ6_003:
  • NZ6_002:

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Joanna Cichy 

Number of co-investigators in the project: 5

Call: OPUS 18 - announced on 2019-09-16

Amount awarded: 2 716 800 PLN

Project start date (Y-m-d): 2020-06-25

Project end date (Y-m-d): 2025-10-24

Project duration:: 64 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. Kallikrein 14 activates the chemoattractant protein chemerin in human skin
    Authors:
    Brzoza P, Tyshchenko M, Kantyka T, Bielecka E, Majewski P, Migaczewski M, Zabel BA, Cichy J.
    Academic press:
    Journal of Biological Chemistry (rok: 2025, tom: vol. 302, issue 1, strony: 111002), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jbc.2025.111002 - link to the publication
  2. 3D Model of Human Epidermis Exposed to Staphylococci Reveals Keratinocyte Responses Unique to Atopy-Associated S. aureus Challenge.
    Authors:
    Piotr Brzoza, Michelle Camacho, Mariia Tyshchenko, Agnieszka Morytko, Mateusz Kwitniewski, Maciej Pastuszczak, Paulina Stepinska, Marcin Migaczewski, Joanna Cichy
    Academic press:
    Allergy (rok: 2025, tom: 80 (8), strony: 2388-2391), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/all.16524 - link to the publication
  3. Molecular Mechanisms of ZC3H12C/Reg-3 Biological Activity and Its Involvement in Psoriasis Pathology
    Authors:
    Wawro, Mateusz, Jakub Kochan, Weronika Sowinska, Aleksandra Solecka, Karolina Wawro, Agnieszka Morytko, Patrycja Kwiecinska, Beata Grygier, Mateusz Kwitniewski, Mingui Fu, Joanna Cichy, and Aneta Kasza.
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 5,66041666666667), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22147311 - link to the publication
  4. Soluble mediators in the function of the epidermal-immune-neuro unit in the skin.
    Authors:
    Oleszycka E, Kwiecien K, Kwiecinska P, Morytko A, Pocalun N, Camacho M, Brzoza P, Zabel BA and Cichy J
    Academic press:
    Frontiers in Immunology (rok: 2022, tom: 13, strony: 46035), Wydawca: Frontiers Media S.A.
    Status:
    Published
    DOI:
    10.3389/fimmu.2022.1003970 - link to the publication

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