Projects funded by the NCN
Co-crystallization and co-amorphization of angiotensin II receptor blockers leading to more soluble compounds with a bifunctional character
2019/33/N/ST5/01602
Keywords:
angiotensin II receptor blockers valsartan losartan telmisartan cocrystals solid dispersions solubility ultrasounds
Descriptors:
- ST5_002:
Panel:
ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering
Host institution :
Uniwersytet Humanistyczno-Przyrodniczy im. Jana Długosza w Częstochowie
woj. śląskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 17 - announced on 2019-03-15
Amount awarded: 210 000 PLN
Project start date (Y-m-d): 2020-01-31
Project end date (Y-m-d): 2025-01-30
Project duration:: 60 months (the same as in the proposal)
Project status: Project completed
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (2)
- New Perspectives for Antihypertensive Sartans as Components of Co-crystals and Co-amorphous Solids with Improved Properties and Multipurpose ActivityAuthors:Marika Turek, Ewa Różycka-Sokołowska, Krzysztof Owsianik, Piotr BałczewskiAcademic press:Molecular Pharmaceutics (rok: 2024, tom: 21, strony: 18-37), Wydawca: ACS PublicationsStatus:PublishedDOI:10.1021/acs.molpharmaceut.3c00959 - link to the publication
- Role of Hydrogen Bonds in Formation of Co-amorphous Valsartan/Nicotinamide Compositions of High Solubility and Durability with Anti-hypertension and Anti-COVID-19 PotentialAuthors:M. Turek, E. Różycka-Sokołowska, M. Koprowski, B. Marciniak, P. BałczewskiAcademic press:Molecular Pharmaceutics (rok: 2021, tom: 18, strony: 1970−1984), Wydawca: ACS PublicationsStatus:PublishedDOI:10.1021/acs.molpharmaceut.0c01096 - link to the publication