Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Multiomic analysis of serum and exosomal biomolecules associated with total body irradiation

2019/33/B/NZ5/00536

Keywords:

ionizing radiation microRNA proteomics exosomes radiotherapy

Descriptors:

  • NZ4_004:
  • NZ2_002:
  • NZ5_005:

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Wojciech Maksymilian Fendler 

Number of co-investigators in the project: 4

Call: OPUS 17 - announced on 2019-03-15

Amount awarded: 1 798 160 PLN

Project start date (Y-m-d): 2020-03-30

Project end date (Y-m-d): 2024-03-29

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (7)
  1. Serum Levels of miR-122-5p and miR-125a-5p Predict Hepatotoxicity Occurrence in Patients Undergoing Autologous Hematopoietic Stem Cell Transplantation.
    Authors:
    Mikulski D, Kościelny K, Dróżdż I, Mirocha G, Nowicki M, Misiewicz M, Perdas E, Strzałka P, Wierzbowska A, Fendler W.
    Academic press:
    International Journal of Molecular Sciences (rok: 2024, tom: Int J Mol Sci. 2024 Apr 15;25(8), strony: 4355), Wydawca: MDPI
    Status:
    Published
    DOI:
    1422-0067/25/8/4355 - link to the publication
  2. Serum miRNA-based signature indicates radiation exposure and dose in humans: A multicenter diagnostic biomarker study
    Authors:
    Zuzanna Nowicka, Bartłomiej Tomasik, David Kozono, Konrad Stawiski, Thomas Johnson, Daphne Haas-Kogan, Marek Ussowicz, Dipanjan Chowdhury, Wojciech Fendler
    Academic press:
    Radiotherapy and oncology (rok: 2023, tom: 185, strony: 109731), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.radonc.2023.109731 - link to the publication
  3. High serum miR-223-3p expression level predicts complete response and prolonged overall survival in multiple myeloma patients undergoing autologous hematopoietic stem cell transplantation.
    Authors:
    Mikulski D, Nowicki M, Dróźdż I, Misiewicz M, Kościelny KP, Okoński K, Krawiec K, Perdas E, Wierzbowska A, Fendler W.
    Academic press:
    Frontiers in Oncology (rok: 2023, tom: Front Oncol . 2023 Sep 27:13, strony: 1250355), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fonc.2023.1250355 - link to the publication
  4. A low thrombospondin-1 serum concentration is related to increased bacteremia risk in lymphoma patients treated with BeEAM/BEAM conditioning regimen and autologous stem cell transplantation.
    Authors:
    Kościelny K, Mikulski D, Nowicki M, Wyka K, Misiewicz M, Perdas E, Wierzbowska A, Fendler W.
    Academic press:
    Transplant Infectious Disease (rok: 2023, tom: Transpl Infect Dis . 2024 Feb;26(1), strony: e14212), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/tid.14212 - link to the publication
  5. Neutrophil to lymphocyte ratio (NLR) impact on the progression-free survival and overall survival of multiple myeloma patients treated with high-dose chemotherapy and autologous stem cell transplantation
    Authors:
    Damian Mikulski, Kacper Kościelny, Mateusz Nowicki, Ewa Wawrzyniak, Marta Kalwas, Monika Kowalik, Mateusz Pryt, Emilia Sęczkowska, Agnieszka Świątek, Agnieszka Wierzbowska, Wojciech Fendler
    Academic press:
    Leukemia & Lymphoma (rok: 2022, tom: 64, strony: 98-106), Wydawca: Taylor & Francis
    Status:
    Published
    DOI:
    10.1080/10428194.2022.2136946 - link to the publication
  6. MicroRNAs predict early complications of autologous hematopoietic stem cell transplantation
    Authors:
    Mikulski D, Nowicki M, Dróżdż I, Perdas E, Strzałka P, Kościelny K, Misiewicz M, Stawiski K, Wierzbowska A, Fendler W.
    Academic press:
    Biomarker Research (rok: 2024, tom: Biomark Res. 2024 Apr 23;12(1), strony: 42), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1186/s40364-024-00585-x. - link to the publication
  7. High serum hsa-miR-361-3p identifies patients at risk of early infection after post-transplant discharge in autologous stem cell transplant recipients
    Authors:
    Damian Mikulski, Kacper Kościelny, Izabela Dróżdż, Mateusz Nowicki, Małgorzata Misiewicz, Ewelina Perdas, Piotr Strzałka, Agnieszka Wierzbowska, Wojciech Fendler
    Academic press:
    Infection & Chemotherapy (rok: 2024, tom: 2024, strony: 2024), Wydawca: Korean Society of Infectious Diseases Korean Society for Antimicrobial Therapy The Korean Society for AIDS Korean Society of Pediatric Infectious Diseases
    Status:
    Published
    DOI:
    10.3947/ic.2024.0021 - link to the publication

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