Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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New calcitriol analogues with unnatural D ring

2018/31/N/ST5/01679

Keywords:

calcitriol hydrindane system ring D nuclear vitamin D receptor bicyclic systems

Descriptors:

  • ST5_23:
  • ST5_16:

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Uniwersytet Warszawski, Wydział Chemii

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Adrian Fabisiak 

Number of co-investigators in the project: 2

Call: PRELUDIUM 16 - announced on 2018-09-14

Amount awarded: 139 100 PLN

Project start date (Y-m-d): 2019-06-21

Project end date (Y-m-d): 2023-06-20

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (1)
  1. Design, synthesis, and biological activity of D-bishomo-1α,25-dihydroxyvitamin D3 analogs and their crystal structures with the vitamin D nuclear receptor
    Authors:
    Adrian Fabisiak, Pawel Brzeminski, Rafal R. Sicinski, Natacha Rochel, Ewa Maj, Beata Filip-Psurska, Joanna Wietrzyk, Lori A. Plum, Hector F. DeLuca
    Academic press:
    European Journal of Medicinal Chemistry (rok: 2024, tom: 274, strony: 116403), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ejmech.2024.116403 - link to the publication