Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Three-dimensional macromolecules orientation by means of infrared (IR) imaging and its significance in cancer microenvironment

2018/31/D/ST4/01833

Keywords:

IR spectroscopy imaging polarization collagen cancer

Descriptors:

  • ST4_3: Molecular architecture and structure
  • ST4_13: Solid-state chemistry, surface physicochemistry
  • ST4_7: Electrochemistry, microfluidics in chemistry, sensors

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Uniwersytet Jagielloński, Narodowe Centrum Promieniowania Synchrotronowego SOLARIS

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Tomasz Wróbel 

Number of co-investigators in the project: 3

Call: SONATA 14 - announced on 2018-09-14

Amount awarded: 999 599 PLN

Project start date (Y-m-d): 2019-07-26

Project end date (Y-m-d): 2024-07-25

Project duration:: 36 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. Super-Resolved 3D Mapping of Molecular Orientation Using Vibrational Techniques
    Authors:
    P Koziol, K Kosowska, D Liberda, F Borondics, TP Wrobel
    Academic press:
    Journal of the American Chemical Society (rok: 2022, tom: 144, strony: 14278-14287), Wydawca: ACS
    Status:
    Published
    DOI:
    10.1021/jacs.2c05306 - link to the publication
  2. Spatially resolved macromolecular orientation in biological tissues using FT-IR imaging
    Authors:
    Karolina Kosowska, Paulina Koziol, Danuta Liberda, Tomasz P. Wrobel
    Academic press:
    Clinical Spectroscopy (rok: 2021, tom: 3, strony: 100013), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.clispe.2021.100013 - link to the publication
  3. Macromolecular orientation in biological tissues using a four-polarization method in FT-IR imaging
    Authors:
    Paulina Koziol, Danuta Liberda, Wojciech M. Kwiatek, Tomasz P. Wrobel
    Academic press:
    Analytical Chemistry (rok: 2020, tom: 92, strony: 13313-13318), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.analchem.0c02591 - link to the publication
  4. Spatial sampling effect on data structure and random forest classification of tissue types in High Definition and Standard Definition FT-IR imaging
    Authors:
    Danuta Liberda, Karolina Kosowska, Paulina Koziol, Tomasz P. Wrobel
    Academic press:
    Chemometrics and Intelligent Laboratory Systems (rok: 2021, tom: 217, strony: 104407), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.chemolab.2021.104407 - link to the publication

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