Glycocalyx damage - the first stage of pathomechanism of endothelial dysfunction; measurements using capillary electrophoresis

2018/31/N/NZ7/01528

Keywords

Descriptors

  • NZ7_12: Prewencja chorób człowieka
  • NZ7_14: Farmacja, farmakoterapia, farmakologia

Panel

NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Karolina Martyna Matyjaszczyk-Gwarda

Number of co-investigators in the project: 3

Call

PRELUDIUM 16 – announced on 2018-09-14

Amount awarded
139 447 PLN
Project start date
2019-07-26
Project end date
2021-07-25
Project duration
24 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Vortex - wytrząsarka.

Information in the final report

Publication in academic press/journals (1)

  1. Simultaneous quantification of selected glycosaminoglycans by butanolysis-based derivatization and LC-SRM/MS analysis for assessing glycocalyx disruption in vitro and in vivo

    Authors:
    Karolina Matyjaszczyk-Gwarda, Agnieszka Kij, Mariola Olkowicz, Benedikt Fels, Kristina Kusche-Vihrog, Maria Walczak, Stefan Chlopicki
    Academic press:
    Talanta (year: 2022, volume: 238, pages: 123008), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.talanta.2021.123008 – link to the publication

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Graphic design and implementation: Jakub Piotrowski