Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Glycocalyx damage - the first stage of pathomechanism of endothelial dysfunction; measurements using capillary electrophoresis

2018/31/N/NZ7/01528

Keywords:

glycocalyx endothelium capillary electrophoresis

Descriptors:

  • NZ7_12: Prevention of human diseases
  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Karolina Matyjaszczyk-Gwarda 

Number of co-investigators in the project: 3

Call: PRELUDIUM 16 - announced on 2018-09-14

Amount awarded: 139 447 PLN

Project start date (Y-m-d): 2019-07-26

Project end date (Y-m-d): 2021-07-25

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Vortex - wytrząsarka.

Information in the final report

  • Publication in academic press/journals (1)
  1. Simultaneous quantification of selected glycosaminoglycans by butanolysis-based derivatization and LC-SRM/MS analysis for assessing glycocalyx disruption in vitro and in vivo
    Authors:
    Karolina Matyjaszczyk-Gwarda, Agnieszka Kij, Mariola Olkowicz, Benedikt Fels, Kristina Kusche-Vihrog, Maria Walczak, Stefan Chlopicki
    Academic press:
    Talanta (rok: 2022, tom: 238, strony: 123008), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.talanta.2021.123008 - link to the publication