Projects funded by the NCN

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Information of the project and the call

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Evaluation of prognostic value of platelet-derived extracellular microvesicles and microRNA in patients witch ischemic stroke of undetermined source- ESUS.

2018/31/B/NZ7/01137

Keywords:

microRNA microvesicles ischemic stroke

Descriptors:

  • NZ7_4:
  • NZ7_1:

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Warszawski Uniwersytet Medyczny, Wydział Lekarski

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Marek Antoni Postuła 

Number of co-investigators in the project: 7

Call: OPUS 16 - announced on 2018-09-14

Amount awarded: 1 748 530 PLN

Project start date (Y-m-d): 2019-07-08

Project end date (Y-m-d): 2024-07-07

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (8)
  • Articles in post-conference publications (3)
  1. The Importance of Non-Coding RNAs in Neurodegenerative Processes of Diabetes-Related Molecular Pathways
    Authors:
    Joanna Jarosz-Popek, Marta Wolska, Aleksandra Gasecka, Pamela Czajka, Daniel Jakubik, Lucia Sharif, Taqwa Adem, Wei-Ling Liu , Dagmara Mirowska-Guzel, Marek Postula, Ceren Eyileten
    Academic press:
    Journal of Clinical Medicine (rok: 2020, tom: 10, strony: 46045), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/jcm10010009 - link to the publication
  2. Long Non-coding RNAs as Promising Therapeutic Approach in Ischemic Stroke: a Comprehensive Review
    Authors:
    Marta Wolska, Joanna Jarosz-Popek, Eva Junger, Zofia Wicik, Tahmina Porshoor, Lucia Sharif , Pamela Czajka, Marek Postula , Dagmara Mirowska-Guzel , Anna Czlonkowska , Ceren Eyileten
    Academic press:
    Molecular Neurobiology (rok: 2020, tom: 58, strony: 1664–1682), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12035-020-02206-8 - link to the publication
  3. Extracellular Vesicle-Derived miRNAs in Ischemic Stroke: Roles in Neuroprotection, Tissue Regeneration, and Biomarker Potential
    Authors:
    Ceren Eyileten, Pamela Czajka, Izabela Domitrz, Agata Wierzchowska-Ciok, Aleksandra Gasecka, Dagmara Mirowska-Guzel, Anna Członkowska, Marek Postula
    Academic press:
    Cellular and Molecular Neurobiology (rok: 2025, tom: 45(1):31, strony: 46042), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s10571-025-01551-3 - link to the publication
  4. An integrative clinical and bioinformatic analysis identifies MicroRNAs as biomarkers of ischemic stroke severity
    Authors:
    Ceren Eyileten, Zofia Wicik, Andleeb Shahzadi, Sara Ahmadova, Pamela Czajka, Izabela Domitrz, Agata Wierzchowska-Ciok, Dagmara Mirowska-Guzel, Anna Czlonkowska, Marek Postula
    Academic press:
    Scientific Reports (rok: 2026, tom: 5,00138888888889, strony: 46039), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1038/s41598-026-36494-2 - link to the publication
  5. Clinical Application of Circular RNAs as Biomarkers in Acute Ischemic Stroke
    Authors:
    Siracusa C, Vono N, Morano MB, Sabatino J, Leo I, Eyileten C, Cianflone E, Postula M, Torella D, De Rosa S.
    Academic press:
    J Pers Med (rok: 2023, tom: 16;13(5):839, strony: 46042), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/jpm13050839 - link to the publication
  6. Discovery and validation of new microRNAs in patients with acute ischemic stroke: MicroRNA profiling and bioinformatics target analysis
    Authors:
    Ceren Eyileten, Zofia Wicik, Aleksandra Gasecka, Maria Teresa Di Martino, Joanna Mucha, Salvatore De Rosa, Iwona Kurkowska-Jastrzebska, Anna Czlonkowska, Marek Postula
    Academic press:
    BMC Med Genomics . (rok: 2026, tom: 1, strony: 13881), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1186/s12920-025-02302-5 - link to the publication
  7. MicroRNA as Potential Biomarkers of Platelet Function on Antiplatelet Therapy: A Review.
    Authors:
    Czajka P, Fitas A, Jakubik D, Eyileten C, Gasecka A, Wicik Z, Siller-Matula JM, Filipiak KJ, Postula M
    Academic press:
    Front Physiol (rok: 2021, tom: 15, strony: 652579), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fphys.2021.652579 - link to the publication
  8. The role of non-coding RNAs in neuroinflammatory process in multiple sclerosis
    Authors:
    Anna Nowak, Zofia Wicik, Marta Wolska, Andleeb Shahzadi, Piotr Szwed, Joanna Jarosz-Popek, Jeffrey Palatini, Marek Postula, Anna Czlonkowska, Dagmara Mirowska-Guzel,Ceren Eyileten
    Academic press:
    Molecular Neurobiology (rok: 2022, tom: 59, strony: 4651–4668), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12035-022-02854-y - link to the publication
  1. . Diagnostic and Predictive Value of Circulating MicroRNAs and their Regulation of the BDNF Signaling Pathway in Stroke Patients.
    Authors:
    C. Eyileten, A. Nowak,. Wicik, S. De Rosa, M. Chong, G. Pare and M. Postuła
    Conference:
    International Society on Thrombosis and Haemostasis (rok: 2023, ), Wydawca: International Society on Thrombosis and Haemostasis
    Data:
    konferencja 24-28.06.2023
    Status:
    Published
  2. Increased levels of platelet function-related miR-16-5p predicts increased severity of ischemic stroke: in silico validation analysis
    Authors:
    C Eyileten, A Nowak, Z Wicik, D Keshwani, M Marszalek, I Domitrz, A Wierzchowska-Ciok, D Mirowska-Guzel, A Czlonkowska, M Postula.
    Conference:
    European Society of Cardiology Congress (rok: 2023, ), Wydawca: European Society of Cardiology
    Data:
    konferencja 26-28 sierpień 2023
    Status:
    Published
  3. Diagnostic and predictive value of circulating microRNAs and their regulation of BDNF signaling pathway in stroke patients
    Authors:
    Mikolaj Marszalek, Disha Keshwani, Ceren Eyileten, Zofia Wicik, Anna Nowak, Salvatore de. Rosa, Dagmara Mirowska-Guzel, Anna Czlonkowska, Guillaume Paré and Marek Postula
    Conference:
    American Society for Pharmacology and Experimental Therapeutics 2023 (rok: 2023, ), Wydawca: The American Society for Pharmacology and Experimental Therapeutics
    Data:
    konferencja 18-21 Maj, 2023
    Status:
    Published

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