Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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Interaction between hypoxia and circadian clock among obstructive sleep apnea patients

2018/31/N/NZ5/03931

Keywords:

obstructive sleep apnea hypoxia circadian rhythm

Descriptors:

  • NZ5_3: Pathogenesis of human diseases

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Agata Gabryelska 

Number of co-investigators in the project: 3

Call: PRELUDIUM 16 - announced on 2018-09-14

Amount awarded: 210 000 PLN

Project start date (Y-m-d): 2019-08-12

Project end date (Y-m-d): 2023-08-11

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (10)
  • Articles in post-conference publications (10)
  1. Evaluation of the chronotype and its predictive factors in patients with obstructive sleep apnea
    Authors:
    Agata Gabryelska, Piotr Białasiewicz, Mikołaj Malicki, Dominik Strzelecki, Marcin Sochal
    Academic press:
    Polish Archives of Internal Medicine (rok: 2023, tom: 133, strony: 16541), Wydawca: Medycyna Praktyczna
    Status:
    Published
    DOI:
    10.20452/pamw.16541 - link to the publication
  2. Factors Affecting Long-Term Compliance of CPAP Treatment—A Single Centre Experience
    Authors:
    Agata Gabryelska, Marcin Sochal, Bartosz Wasik, Przemysław Szczepanowski, Piotr Białasiewicz
    Academic press:
    Journal of Clinical Medicine (rok: 2021, tom: 11, strony: 139), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/jcm11010139 - link to the publication
  3. Influence of one-night CPAP therapy on the changes of HIF-1α protein in obstructive sleep apnea patients – a pilot study
    Authors:
    Agata Gabryelska, Robert Stawski, Marcin Sochal, Bartosz Szmyd, Piotr Białasiewicz
    Academic press:
    Journal of Sleep Research (rok: 2020, tom: 29, strony: 45293), Wydawca: Wiley Online Library
    Status:
    Published
    DOI:
    10.1111/jsr.12995 - link to the publication
  4. Evaluation of HIF-1 Involvement in the BDNF and ProBDNF Signaling Pathways among Obstructive Sleep Apnea Patients
    Authors:
    Agata Gabryelska, Marcin Sochal
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23, strony: 14876), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms232314876 - link to the publication
  5. The impact of glucocorticoids and statins on sleep quality
    Authors:
    Bartosz Szmyd, Magdalena Rogut, Piotr Białasiewicz, Agata Gabryelska
    Academic press:
    Sleep Medicine Reviews (rok: 2021, tom: 55, strony: 45301), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.smrv.2020.101380 - link to the publication
  6. Patients with obstructive sleep apnea present with chronic up-regulation of serum HIF-1α protein
    Authors:
    Agata Gabryelska, Bartosz Szmyd, Janusz Szemraj, Robert Stawski, Marcin Sochal, Piotr Białasiewicz
    Academic press:
    Journal of Clinical Sleep Medicine (rok: 2020, tom: 16, strony: 45308), Wydawca: American Academy of Sleep Medicine
    Status:
    Published
    DOI:
    10.5664/jcsm.8682 - link to the publication
  7. Relationship between HIF-1 and circadian clock proteins in obstructive sleep apnea patients – preliminary study
    Authors:
    Agata Gabryelska, Marcin Sochal, Szymon Turkiewicz, Piotr Białasiewicz
    Academic press:
    Journal of Clinical Medicine (rok: 2020, tom: 9, strony: 45298), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/jcm9051599 - link to the publication
  8. Serum Hypoxia-Inducible Factor-1α protein level as a diagnostic marker of obstructive sleep apnea
    Authors:
    Agata Gabryelska, Bartosz Szmyd, Michał Panek, Janusz Szemraj, Piotr Kuna, Piotr Białasiewicz
    Academic press:
    Polskie Archiwum Medycyny Wewnętrznej (rok: 2020, tom: 130, strony: 158-160), Wydawca: Medycyna Praktyczna
    Status:
    Published
    DOI:
    10.20452/pamw.15104 - link to the publication
  9. Evaluation of daytime sleepiness and insomnia symptoms in OSA patients with a characterization of symptom-defined phenotypes and their involvement in depression comorbidity
    Authors:
    Agata Gabryelska, Szymon Turkiewicz, Piotr Białasiewicz, Filip Grzybowski,Dominik Strzelecki, Marcin Sochal
    Academic press:
    Frontiers in Psychiatry (rok: 2023, tom: brak, strony: brak), Wydawca: Frontiers
    Status:
    Submitted
  10. Disruption of Circadian Rhythm Genes in Obstructive Sleep Apnea Patients—Possible Mechanisms Involved and Clinical Implication
    Authors:
    Agata Gabryelska, Szymon Turkiewicz, Filip Franciszek Karuga, Marcin Sochal, Dominik Strzelecki, Piotr Białasiewicz
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 23, strony: 709), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms23020709 - link to the publication
  1. Evaluation of circadian clock proteins and the effect of CPAP treatment among OSA patients
    Authors:
    Agata Gabryelska, Szymon Turkiewicz, Piotr Białasiewicz, Dominik Strzelecki, Marcin Sochal
    Conference:
    31st annual Congress of the European College of Neuropsychopharmacology (ECNP) 2023 (rok: 2023, ), Wydawca: Elsevier
    Data:
    konferencja 07-10.10.2023
    Status:
    Accepted for publication
  2. Association of HIF-1 Alpha and Beta Subunits with Clock and BMAL1 Proteins in Obstructive Sleep Apnea Patients
    Authors:
    Agata Gabryelska, Marcin Sochal, Szymon Turkiewicz, Piotr Białasiewicz
    Conference:
    34th Annual Meeting of the Associated Professional Sleep Societies (SLEEP 2020) (rok: 2020, ), Wydawca: Oxford University Press
    Data:
    konferencja 27-08-2020 - 30-08-2020
    Status:
    Published
  3. Characterization of insomnia phenotype among obstructive sleep apnea patients
    Authors:
    Agata Gabryelska, Marcin Sochal, Oliwio Weiner, Adrianna Owczarek, Piotr Białasiewicz
    Conference:
    25th Congress of the European Sleep Research Society (ESRS 2020) (rok: 2020, ), Wydawca: Wiley Online Library
    Data:
    konferencja 22-09-2020 - 24-09-2020
    Status:
    Published
  4. Association of HIF-1 Alpha and Beta Subunits with PER1 and CRY1 Proteins in Obstructive Sleep Apnea Patients
    Authors:
    Agata Gabryelska, Marcin Sochal, Piotr Białasiewicz
    Conference:
    CHEST Congress 2020 (rok: 2020, ), Wydawca: Elsevier
    Data:
    konferencja 25-06-2020 - 27-06-2020
    Status:
    Published
  5. Disruption of Circadian Clock Proteins in Obstructive Sleep Apnea Patients
    Authors:
    Agata Gabryelska, Marcin Sochal, Piotr Białasiewicz
    Conference:
    34th Annual Meeting of the Associated Professional Sleep Societies (SLEEP 2020) (rok: 2020, ), Wydawca: Oxford University Press
    Data:
    konferencja 27-08-2020 - 30-08-2020
    Status:
    Published
  6. Hypoxia as a possible mechanism of circadian clock dysregulation among Obstructive Sleep Apnea patients
    Authors:
    Agata Gabryelska, Filip Franciszek Karuga, Piotr Kaczmarski, Dominik Strzelecki
    Conference:
    American Psychiatric Association (APA) Annual Meeting 2023 (rok: 2023, ), Wydawca: American Psychiatric Association Publishing
    Data:
    konferencja 20-24.05.2023
    Status:
    Published
  7. Association between obstructive sleep apnea severity, Diabetes mellitus type 2 and circadian clock protein levels
    Authors:
    Filip Franciszek Karuga, Marcin Sochal, Piotr Białasiewicz, Dominik Strzelecki, Agata Gabryelska
    Conference:
    Sleep Europe 2022 (rok: 2022, ), Wydawca: Wiley
    Data:
    konferencja 27-30.09.2022
    Status:
    Published
  8. Chronic upregulation of circadian clock protein per1 among OSA patients
    Authors:
    Agata Gabryelska, Marcin Sochal, Piotr Bialasiewicz
    Conference:
    29th European Congress of Psychiatry (rok: 2021, ), Wydawca: Cambridge University Press
    Data:
    konferencja 4,2021
    Status:
    Published
  9. Evaluation of chronotype and its predictive factors among Obstructive Sleep Apnea patients
    Authors:
    Agata Gabryelska, Piotr Białasiewicz, Dominik Strzelecki, Marcin Sochal
    Conference:
    American Psychiatric Association (APA) Annual Meeting 2024 (rok: 2024, ), Wydawca: American Psychiatric Association Publishing
    Data:
    konferencja 04-08.04.2024
    Status:
    Submitted
  10. Evaluation of daytime sleepiness and insomnia symptoms in OSA patients with a characterization of symptom-defined phenotypes and their involvement in depression comorbidity
    Authors:
    Agata Gabryelska, Szymon Turkiewicz, Piotr Białasiewicz, Filip Grzybowski, Dominik Strzelecki, Marcin Sochal
    Conference:
    32nd European Congress of Psychiatry (EPA) 2024 (rok: 2024, ), Wydawca: Cambridge University Press
    Data:
    konferencja 06-09.04.2024
    Status:
    Submitted