Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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The role of FOXO3a transcription factor in the induction of oxidative stress and invasiveness of prostate cancer cells by zearalenol (a-ZOL and B-ZOL).

2018/31/N/NZ7/01886

Keywords:

FOXO3a zearalenone zearalenol mycotoxins prostate cancer

Descriptors:

  • NZ7_15: Toxicology
  • NZ7_12: Prevention of human diseases
  • NZ7_2: Environment and health risks

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Medyczny w Łodzi, Wydział Nauk Biomedycznych i Kształcenia Podyplomowego

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Dominika Habrowska-Górczyńska 

Number of co-investigators in the project: 2

Call: PRELUDIUM 16 - announced on 2018-09-14

Amount awarded: 210 000 PLN

Project start date (Y-m-d): 2019-07-11

Project end date (Y-m-d): 2024-07-10

Project duration:: 36 months (the same as in the proposal)

Project status: Pending project

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  1. FOXO3a/PI3K/Akt pathway participates in the ROS- induced apoptosis triggered by the active metabolites of zearalenone: α-ZEL and β-ZEL
    Authors:
    Dominika Ewa Habrowska-Górczyńska, Marta Justyna Kozieł, Kinga Anna Urbanek, Karolina Kowalska, Agnieszka Wanda Piastowska-Ciesielska
    Academic press:
    Scientific Reports , Wydawca: Nature
    Status:
    Submitted
  2. FOXO3a and Its Regulators in Prostate Cancer
    Authors:
    Dominika Ewa Habrowska-Górczyńska, Marta Justyna Kozieł, Karolina Kowalska, Agnieszka Wanda Piastowska-Ciesielska
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 12530), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms222212530 - link to the publication