Projects funded by the NCN
The role of FOXO3a transcription factor in the induction of oxidative stress and invasiveness of prostate cancer cells by zearalenol (a-ZOL and B-ZOL).
2018/31/N/NZ7/01886
Keywords:
FOXO3a zearalenone zearalenol mycotoxins prostate cancer
Descriptors:
- NZ7_15: Toxicology
- NZ7_12: Prevention of human diseases
- NZ7_2: Environment and health risks
Panel:
NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution :
Uniwersytet Medyczny w Łodzi, Wydział Nauk Biomedycznych i Kształcenia Podyplomowego
woj. łódzkie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 16 - announced on 2018-09-14
Amount awarded: 210 000 PLN
Project start date (Y-m-d): 2019-07-11
Project end date (Y-m-d): 2024-07-10
Project duration:: 36 months (the same as in the proposal)
Project status: Project completed
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (2)
- FOXO3a and Its Regulators in Prostate CancerAuthors:Dominika Ewa Habrowska-Górczyńska, Marta Justyna Kozieł, Karolina Kowalska, Agnieszka Wanda Piastowska-CiesielskaAcademic press:International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 12530), Wydawca: MDPIStatus:PublishedDOI:10.3390/ijms222212530 - link to the publication
- FOXO3a/PI3K/Akt pathway participates in the ROS- induced apoptosis triggered by the active metabolites of zearalenone: α-ZEL and β-ZELAuthors:Dominika Ewa Habrowska-Górczyńska, Marta Justyna Kozieł, Kinga Anna Urbanek, Karolina Kowalska, Agnieszka Wanda Piastowska-CiesielskaAcademic press:Scientific Reports , Wydawca: NatureStatus:SubmittedDOI:brak - link to the publication