Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Functionalized nanoparticles of noble metals as stimulators of immune response in HSV-1/2 infection

2018/31/B/NZ6/02606

Keywords:

HSV-1/2 silver nanoparticles gold nanoparticles tannic acid

Descriptors:

  • NZ6_5:
  • NZ6_1:

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Wojskowy Instytut Higieny i Epidemiologii im. gen. Karola Kaczkowskiego

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Małgorzata Krzyżowska 

Number of co-investigators in the project: 7

Call: OPUS 16 - announced on 2018-09-14

Amount awarded: 1 814 430 PLN

Project start date (Y-m-d): 2019-11-04

Project end date (Y-m-d): 2023-11-03

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (8)
  1. Epigallocatechin Gallate-Modified Silver Nanoparticles Show Antiviral Activity against Herpes Simplex Type 1 and 2
    Authors:
    Krzyzowska M, Janicka M, Chodkowski M, Patrycy M, Obuch-Woszczatyńska O, Tomaszewska E, Ranoszek-Soliwoda K, Celichowski G, Grobelny J.
    Academic press:
    Viruses (rok: 2023, tom: 10, strony: 15), Wydawca: mdpi
    Status:
    Published
    DOI:
    10.3390/v15102024. - link to the publication
  2. Quantification of the Surface Coverage of Gold Nanoparticles with Mercaptosulfonates Using Isothermal Titration Calorimetry (ITC).
    Authors:
    Tomaszewska E, Stępniak A, Wróbel D, Bednarczyk K, Maly J, Krzyżowska M, Celichowski G, Grobelny J, Ranoszek-Soliwoda K.
    Academic press:
    J Phys Chem B. (rok: 2024, tom: 128, strony: 10904-10914), Wydawca: ACS Publications
    Status:
    Published
    DOI:
    10.1021/acs.jpcb.4c03365 - link to the publication
  3. Adjuvanticity of Tannic Acid-Modified Nanoparticles Improves Effectiveness of the Antiviral Response
    Authors:
    Janicka M, Chodkowski M, Osinska A, Bylinska K, Obuch-Woszczatyńska O, Patrycy M, Chodaczek G, Ranoszek-Soliwoda K, Tomaszewska E, Celichowski G, Grobelny J, Cymerys J, Krzyżowska M.
    Academic press:
    International Journal of Nanomedicine (rok: 2025, tom: 20, strony: 3977–3997), Wydawca: Dovepress
    Status:
    Published
    DOI:
    10.2147/IJN.S512509 - link to the publication
  4. Lactoferrin-Functionalized Noble Metal Nanoparticles as New Antivirals for HSV-2 Infection
    Authors:
    Krzyzowska M, Chodkowski M, Janicka M, Dmowska D, Tomaszewska E, Ranoszek-Soliwoda K, Bednarczyk K, Celichowski G, Grobelny J.
    Academic press:
    Microorganisms (rok: 2022, tom: 10, strony: 110), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/microorganisms10010110 - link to the publication
  5. Anti-HSV Activity of Metallic Nanoparticles Functionalized with Sulfonates vs. Polyphenols
    Authors:
    Tomaszewska E, Ranoszek-Soliwoda K, Bednarczyk K, Lech A, Janicka M, Chodkowski M, Psarski M, Celichowski G, Krzyzowska M, Grobelny J.
    Academic press:
    Int J Mol Sci (rok: 2022, tom: 23, strony: 13104), Wydawca: mdpi
    Status:
    Published
    DOI:
    10.3390/ijms232113104. - link to the publication
  6. Systematic Studies of Gold Nanoparticles Functionalised with Thioglucose and its Cytotoxic Effect
    Authors:
    Emilia Tomaszewska,[a] Katarzyna Ranoszek-Soliwoda,[a] Krzysztof Sztandera,[c] Paulina Błażałek,[b] Rafał Głowacki,[b] Anna Janaszewska,[c] Beata Janasik,[d] Grzegorz Celichowski,[a] Wojciech Wąsowicz,[d] Barbara Klajnert-Maculewicz,*[c] and Jarosław Grobelny*[
    Academic press:
    Materials Science inc. Nanomaterials & Polymers (rok: 2021, tom: 6, strony: 45666), Wydawca: Wiley-VCH GmbH
    Status:
    Published
    DOI:
    10.1002/slct.202100034 - link to the publication
  7. The Influence of the AgNPs Ligand on the Antiviral Activity Against HSV-2
    Authors:
    Tomaszewska E, Bednarczyk K, Janicka M, Chodkowski M, Krzyzowska M, Celichowski G, Grobelny J, Ranoszek-Soliwoda K.
    Academic press:
    Int J Nanomedicine (rok: 2025, tom: 20, strony: 2659-2671), Wydawca: Dove
    Status:
    Published
    DOI:
    10.2147/IJN.S496050 - link to the publication
  8. Functionalized Noble Metal Nanoparticles for the Treatment of Herpesvirus Infection.
    Authors:
    Janicka M, Ranoszek-Soliwoda K, Chodaczek G, Antos-Bielska M, Brytan M, Tomaszewska E, Celichowski G, Grobelny J, Cymerys J, Krzyżowska M, Chodkowski M.
    Academic press:
    Microorganisms (rok: 2022, tom: 10, strony: 2161), Wydawca: mdpi
    Status:
    Published
    DOI:
    10.3390/microorganisms10112161. - link to the publication

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