Projects funded by the NCN
Modified tumor-derived exosomes as novel nanocarriers of anti-tumor molecules for the reprogramming of tumor microenvironment
2018/30/E/NZ5/00711
Keywords:
tumor-derived exosomes dendritic cells immunotherapy IL-12 IL-18 TGF-β IL-10 murine colon carcinoma MC38 murine lung carcinoma LLC
Descriptors:
- NZ5_9: Other related subjects
Panel:
NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)
Host institution :
Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk
woj. dolnośląskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 7
Call: SONATA BIS 8 - announced on 2018-06-15
Amount awarded: 2 414 100 PLN
Project start date (Y-m-d): 2019-04-25
Project end date (Y-m-d): 2025-04-24
Project duration:: 48 months (the same as in the proposal)
Project status: Pending project
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (1)
- Treatment with lentiviral vectors encoding shRNA against interleukin 10 modulates the immunosuppressive activity of murine colon carcinoma‑associated myeloid‑derived suppressor cellsAuthors:Natalia Anger‑Góra, Katarzyna Węgierek‑Ciura, Agnieszka Szczygieł, Jagoda Mierzejewska, Elżbieta Pajtasz‑Piasecka, Joanna RossowskaAcademic press:Oncology Letters (rok: 2021, tom: 22, strony: 582: 1-16), Wydawca: Spandidos PublicationsStatus:PublishedDOI:10.3892/ol.2021.12843 - link to the publication