Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Katalizowane zasadami Lewisa asymetryczne reakcje aromatycznych substratów karbonylowych

2018/30/Q/ST5/00466

Keywords:

Lewis bases aromatic compounds asymmetric catalysis dearomatization aminocatalysis

Descriptors:

  • ST5_23:

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Politechnika Łódzka, Wydział Chemiczny

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Łukasz Albrecht 

Number of co-investigators in the project: 4

Call: SHENG 1 - announced on 2018-06-15

Amount awarded: 1 456 400 PLN

Project start date (Y-m-d): 2019-07-22

Project end date (Y-m-d): 2023-07-21

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. System do chromatografii flash (180 000 PLN)
  2. Pompa próżniowa (9 000 PLN)
  3. Wyparka obrotowa (20 000 PLN)
  4. Membranowa pompa próżniowa z kontrolerem próżni (34 000 PLN)
  5. Kolumny HPLC z chiralnym wypełnieniem (20 000 PLN)

Information in the final report

  • Publication in academic press/journals (12)
  1. Dearomative, aminocatalytic normal-electron-demand aza-Diels-Alder cycloaddition in the synthesis of tetrahydrofuropyridines
    Authors:
    Mateusz Dyguda, Artur Przydacz, Łukasz Albrecht
    Academic press:
    Chemical Communications (rok: 2023, tom: 59, strony: 12903-12906), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/D3CC03946C - link to the publication
  2. Lewis Basic Amine Catalyzed Aza-Michael Reaction of Indole- and Pyrrole-3-carbaldehydes
    Authors:
    Chang-Jiang Xu , Wei Du , Łukasz Albrecht , Ying-Chun Chen
    Academic press:
    Synthesis (rok: 2020, tom: 52, strony: 2650-2661), Wydawca: Thieme
    Status:
    Published
    DOI:
    10.1055/s-0040-1707176 - link to the publication
  3. NHC-Catalyzed 1,4-Elimination in the Dearomative Activation of 3-Furaldehydes towards (4+2)-Cycloadditions
    Authors:
    Artur Przydacz, Aleksandra Topolska, Anna Skrzyńska, Łukasz Albrecht
    Academic press:
    Advanced Synthesis & Catalysis (rok: 2022, tom: 364, strony: 1434-1439), Wydawca: Wiley-VCH
    Status:
    Published
    DOI:
    10.1002/adsc.202101338 - link to the publication
  4. Differentiating Catalysis in the Dearomative [4 + 2]-Cycloaddition Involving Enals and Heteroaromatic Aldehydes
    Authors:
    Aleksandra Topolska, Sebastian Frankowski, Łukasz Albrecht
    Academic press:
    Organic Letters (rok: 2022, tom: 24, strony: 955-959), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.orglett.1c04328 - link to the publication
  5. Vinylogous Hydrazone Strategy in Stereoselective Synthesis of 2,3-Dihydro-1H-pyrrolizines – An Organocatalytic, Metal-Free Route to Ketorolac
    Authors:
    Justyna Kowalska, Beata Łukasik, Sebastian Frankowski, Lesław Sieroń, Łukasz Albrecht
    Academic press:
    Advanced Synthesis & Catalysis (rok: 2022, tom: 364, strony: 3607-3616), Wydawca: Wiley-VCH
    Status:
    Published
    DOI:
    10.1002/adsc.202200727 - link to the publication
  6. Asymmetric [4+2]-Cycloaddition of Anthracene Derivatives via Hydrazone Activation
    Authors:
    Beata Łukasik, Jakub Ossowski, Sebastian Frankowski, Łukasz Albrecht
    Academic press:
    Adv. Synth. Catal. (rok: 2023, tom: -, strony: -), Wydawca: Wiley-VCH
    Status:
    Accepted for publication
    DOI:
    10.1002/adsc.202300774 - link to the publication
  7. Doubly vinylogous and doubly rearomative functionalization of 2-alkyl-3-furfurals
    Authors:
    Artur Przydacz, Mateusz Dyguda, Aleksandra Topolska, Anna Skrzyńska, Chang-Jiang Xu, Ying-Chun Chen, Łukasz Albrecht
    Academic press:
    Organic & Biomolecular Chemistry (rok: 2020, tom: 18, strony: 5816-5821), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/D0OB00788A - link to the publication
  8. Vinylogous hydrazone strategy for the organocatalytic alkylation of heteroaromatic derivatives
    Authors:
    Beata Łukasik, Justyna Kowalska, Sebastian Frankowski, Łukasz Albrecht
    Academic press:
    Chemical Communications (rok: 2021, tom: 57, strony: 6312-6315), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/D1CC01923F - link to the publication
  9. Aminocatalytic Alkylation of Indene-2-Carbaldehydes vi aPentaenamine Activation
    Authors:
    Artur Przydacz, Aleksandra Topolska, Anna Skrzyńska, SebastianFrankowski, ŁukaszAlbrecht
    Academic press:
    Advanced Synthesis & Catalysis (rok: 2022, tom: 364, strony: 974-979), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/adsc.202101296 - link to the publication
  10. Asymmetric Formal Vinylogous Iminium Ion Activation for Vinyl-Substituted Heteroaryl and Aryl Aldehydes
    Authors:
    Xin-Yue Gao, Ru-Jie Yan, Ben-Xian Xiao, Wei Du, Łukasz Albrecht, and Ying-Chun Chen
    Academic press:
    Organic Letters (rok: 2019, tom: 21, strony: 9628-9632), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.orglett.9b03794 - link to the publication
  11. Enantioselective H-bond-directed vinylogous iminium ion strategy for the functionalization of vinyl-substituted heteroaryl aldehydes
    Authors:
    Anna Skrzyńska, Sebastian Frankowski, Aleksandra Topolska, Mateusz Dyguda, Xin-Yue Gao, Chang-Jiang Xu, Ying-Chun Chen and Łukasz Albrecht
    Academic press:
    Chemical Communications (rok: 2021, tom: 57, strony: 1667-1670), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/D0CC07765H - link to the publication
  12. Hydrazone Activation in the Aminocatalytic Cascade Reaction for the Synthesis of Tetrahydroindolizines
    Authors:
    Justyna Kowalska, Beata Łukasik, Sebastian Frankowski, Łukasz Albrecht
    Academic press:
    Organic Letters (rok: 2024, tom: 26, strony: 814−818), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.orglett.3c03911 - link to the publication

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