Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Synthetic alakloid analogues: aminoalcohols beyond the chiral pool

2018/30/E/ST5/00242

Keywords:

Cinchona alkaloids mefloquine asymmetric synthesis

Descriptors:

  • ST5_23:
  • ST5_18:

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Politechnika Wrocławska

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Przemysław Boratyński 

Number of co-investigators in the project: 10

Call: SONATA BIS 8 - announced on 2018-06-15

Amount awarded: 1 999 547 PLN

Project start date (Y-m-d): 2019-09-16

Project end date (Y-m-d): 2025-09-15

Project duration:: 60 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (5)
  1. Chiral vicinal diamines derived from mefloquine
    Authors:
    Dawid Kucharski, Rafał Kowalczyk, Przemysław Boratyński
    Academic press:
    The Journal of Organic Chemistry (rok: 2021, tom: 86, strony: 10654-10664), Wydawca: ACS
    Status:
    Published
    DOI:
    10.1021/acs.joc.1c01316 - link to the publication
  2. Development of Mefloquine-Based Bifunctional Secondary Amine Organocatalysts for Enantioselective Michael and Friedel–Crafts Reactions
    Authors:
    Kucharski, D. J.; Suchanek, R.; Kowalczyk, R.; Boratyński, P. J.
    Academic press:
    the Journal of Organic Chemistry (rok: 2024, tom: 89, strony: 111-123), Wydawca: ACS
    Status:
    Published
    DOI:
    10.1021/acs.joc.3c01791 - link to the publication
  3. (1R/S,7aS/R)-1-Benzyl-1-[2,8-bis(trifluoromethyl)quinolin-4-yl]-hexahydro-oxazolo[3,4-a]pyridin-3-one
    Authors:
    Kucharski, D. J.; Boratyński, P. J.
    Academic press:
    Molbank (rok: 2024, tom: 2024, strony: M1756), Wydawca: mdpi
    Status:
    Published
    DOI:
    10.3390/M1756 - link to the publication
  4. Stereoselective domino rearrangement peri-annulation of Cinchona alkaloid derivatives with 8-bromo-1-naphthyl Grignard.
    Authors:
    Przemysław Boratyński
    Academic press:
    The Journal of Organic Chemistry (rok: 2022, tom: 87, strony: 11602-11607), Wydawca: ACS
    Status:
    Published
    DOI:
    10.1021/acs.joc.2c01249 - link to the publication
  5. A review of modifications of quinoline antimalarials: mefloquine and (hydroxy)chloroquine
    Authors:
    Dawid Kucharski, Michalina K. Jaszczak, Przemysław Boratyński
    Academic press:
    Molecules (rok: 2022, tom: 27, strony: 1003), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules27031003 - link to the publication

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