Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The role of Tks5 protein in organization of the muscle postsynaptic machinery

2018/29/N/NZ4/02724

Keywords:

Neuromuscular junction Tks5 synaptogenesis acetylcholine receptors

Descriptors:

  • NZ3_1: Cell biology
  • NZ3_6: Cell neurobiology
  • NZ4_9: Systems neurobiology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Biologii Doświadczalnej im. M. Nenckiego Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Marcin Pęziński 

Number of co-investigators in the project: 2

Call: PRELUDIUM 15 - announced on 2018-03-15

Amount awarded: 210 000 PLN

Project start date (Y-m-d): 2019-01-28

Project end date (Y-m-d): 2022-01-27

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Platforma bujająca do analizy Western Blot (15 000 PLN)
  2. Łaźnia wodna.

Information in the final report

  • Publication in academic press/journals (2)
  1. An improved method for culturing myotubes on laminins for the robust clustering of postsynaptic machinery
    Authors:
    Marcin Pęziński, Patrycja Daszczuk, Bhola Shankar Pradhan, Hanns Lochmüller, Tomasz J. Prószyński
    Academic press:
    Scientific Reports (rok: 2020, tom: 10, strony: 45304), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/s41598-020-61347-x - link to the publication
  2. Tks5 Regulates Synaptic Podosome Formation and Stabilization of the Postsynaptic Machinery at the Neuromuscular Junction
    Authors:
    Marcin Pęziński; Kamila Maliszewska-Olejniczak; Patrycja Daszczuk; Paula Mazurek; Paweł Niewiadomski and Maria Jolanta Rędowicz
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 12051), Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
    Status:
    Published
    DOI:
    10.3390/ijms222112051 - link to the publication

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