Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The chemoselective synthesis of previously inaccessible imines and iminium ions from inert amides - their useful tranformations and practical utility

2018/29/N/ST5/01938

Keywords:

activation of amides inaccessible aldehydes imines reduction to imines amines functionalization bioisosteres

Descriptors:

  • ST5_23:

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Instytut Chemii Organicznej Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Paweł Czerwiński 

Number of co-investigators in the project: 2

Call: PRELUDIUM 15 - announced on 2018-03-15

Amount awarded: 132 000 PLN

Project start date (Y-m-d): 2019-01-24

Project end date (Y-m-d): 2021-09-23

Project duration:: 32 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. mieszadło magnetyczne (3 000 PLN)
  2. komputer typu laptop (3 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  1. A long-sought reactivity of a sodium hydride
    Authors:
    Paweł Czerwiński, Bartłomiej Furman
    Academic press:
    Trends in Chemistry (rok: 2020, tom: 2, strony: 782-784), Wydawca: Cell Press
    Status:
    Published
    DOI:
    10.1016/j.trechm.2020.07.001 - link to the publication
  2. Mechanochemical generation of zirconocene chloride hydride and its in-situ use for the reductive functionalization of fluoroacetamides
    Authors:
    Paweł Czerwiński, Justyna Najczuk, Bartłomiej Furman
    Academic press:
    Green Chemistry (rok: 2021, tom: -, strony: -), Wydawca: Royal Society of Chemistry
    Status:
    Submitted
    DOI:
    brak - link to the publication
  3. Overcoming inaccessibility of fluorinated imines – synthesis of functionalized amines from readily available fluoroacetamides
    Authors:
    Paweł Czerwiński, Bartłomiej Furman
    Academic press:
    Chemical Communications (rok: 2019, tom: 55, strony: 9436-9439), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/C9CC04111G - link to the publication
  4. Reductive Functionalization of Amides in Synthesis and for Modification of Bioactive Compounds
    Authors:
    Paweł Czerwiński, Bartłomiej Furman
    Academic press:
    Frontiers in Chemistry (rok: 2021, tom: 9, strony: 655849), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fchem.2021.655849 - link to the publication

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