Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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Analysis of molecular mechanism of HER2-dependent response of DCIS (Ductal Carcinoma in situ) cells to inflammatory stimulatiob

2018/29/N/NZ3/02407

Keywords:

DCIS HER2 inflammation

Descriptors:

  • NZ3_1: Cell biology
  • NZ3_7: Signal transduction

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Dominika Piasecka 

Number of co-investigators in the project: 2

Call: PRELUDIUM 15 - announced on 2018-03-15

Amount awarded: 140 000 PLN

Project start date (Y-m-d): 2019-02-04

Project end date (Y-m-d): 2022-02-03

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  1. Upregulation of HIF1-α via an NF-κB/COX2 pathway confers proliferative dominance of HER2-negative ductal carcinoma in situ cells in response to inflammatory stimuli
    Authors:
    Dominika Piasecka, Marcin Braun, Magdalena Mieszkowska, Lukasz Kowalczyk, Janusz Kopczynski, Radzislaw Kordek, Rafal Sadej, Hanna M. Romanska
    Academic press:
    Neoplasia (rok: 2020, tom: 22, strony: 576-589), Wydawca: Elsevier (Science Direct)
    Status:
    Published
    DOI:
    10.1016/j.neo.2020.09.003 - link to the publication
  2. Subtype-specific tumour immune microenvironment in risk of recurrence of ductal carcinoma in situ: prognostic value of HER2
    Authors:
    Julia Solek, Adrianna Cieslak, Jedrzej Chrzanowski, Aleksandra Zielinska, Dominika Piasecka, Marcin Braun, Rafał Sadej, Hanna M. Romanska
    Academic press:
    Biomedicines (rok: 2022, tom: -, strony: -), Wydawca: MDPI
    Status:
    Submitted