Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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Analysis of let-7 family miRNA expression in the context of BRAF mutation and potencial use of cf-DNA and miRNA in liquid biopsy as marker in diagnosis of papillary thyroid cancer.

2018/29/N/NZ2/02015

Keywords:

miRNA papillary thyroid cancer liquid biopsy cf-DNA let-7

Descriptors:

  • NZ5_3: Pathogenesis of human diseases
  • NZ2_1: Molecular genetics
  • NZ5_5: Diagnostics in human diseases

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Ewelina Perdas 

Number of co-investigators in the project: 2

Call: PRELUDIUM 15 - announced on 2018-03-15

Amount awarded: 140 000 PLN

Project start date (Y-m-d): 2019-01-31

Project end date (Y-m-d): 2021-01-30

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  1. Altered Levels of Circulating Nuclear and Mitochondrial DNA in Patients With Papillary Thyroid Cancer
    Authors:
    Ewelina Perdas, Robert Stawski, Krzysztof Kaczka, Dariusz Nowak, Maria Zubrzycka
    Academic press:
    Scientific Reports (rok: 2019, tom: 9, strony: 14438), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/s41598-019-51000-7 - link to the publication
  2. Analysis of Let-7 Family miRNA in Plasma as Potential Predictive Biomarkers of Diagnosis for Papillary Thyroid Cancer
    Authors:
    Perdas, E.; Stawski, R.; Kaczka, K.; Zubrzycka, M.
    Academic press:
    Diagnostics (rok: 2020, tom: 10, strony: 130), Wydawca: Multidisciplinary Digital Publishing Institute
    Status:
    Published
    DOI:
    10.3390/diagnostics10030130 - link to the publication