Projects funded by the NCN
Gain-of-function complement C2 mutant as a supporter of anti-CD20 therapy in murine lymphoma model
2018/29/N/NZ6/01413
Keywords:
complement system monoclonal antibodies cancer
Descriptors:
- NZ6_1: Adaptive and innate immunity
- NZ6_2: Clinical immunology
Panel:
NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology
Host institution :
Gdański Uniwersytet Medyczny, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego
woj. pomorskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 15 - announced on 2018-03-15
Amount awarded: 210 000 PLN
Project start date (Y-m-d): 2019-03-06
Project end date (Y-m-d): 2022-03-05
Project duration:: 36 months (the same as in the proposal)
Project status: Project settled
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (1)
- In Silico Designed Gain-of-Function Variants of Complement C2 Support Cytocidal Activity of Anticancer Monoclonal AntibodiesAuthors:Aleksandra Urban, Alan Majeranowski, Grzegorz Stasiłojć , Patrycja Koszałka, Anna Felberg, Michał Taszner, Jan M Zaucha, Marcin OkrójAcademic press:Cancers (Basel) (rok: 2022, tom: 14, strony: 5), Wydawca: MDPIStatus:PublishedDOI:10.3390/cancers14051270 - link to the publication