Projects funded by the NCN
Budowa chemiczna i stereostruktura kowalencyjnych adduktów wybranych przeciwnowotworowych pochodnych akrydyny z zasadami DNA
2018/28/T/ST5/00165
Keywords:
Descriptors:
- ST5_16:
- ST5_22:
- NZ7_14: Pharmacy, pharmacotherapy, pharmacology
Panel:
ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering
Host institution :
Politechnika Gdańska, Wydział Chemiczny
woj. pomorskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: ETIUDA 6 - announced on 2017-12-15
Amount awarded: 97 586 PLN
Project start date (Y-m-d): 2018-10-01
Project end date (Y-m-d): 2019-03-31
Project duration:: 6 months (the same as in the proposal)
Project status: Project settled
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (1)
- A strong preference for the TA/TA dinucleotide step discovered for an acridine-based, potent antitumor dsDNA intercalator, C-1305: NMR-driven structural and sequence-specificity studiesAuthors:Laskowski Tomasz, Andrałojć Witold, Grynda Jakub, Gwarda Paulina, Mazerski Jan, Gdaniec ZofiaAcademic press:Scientific Reports (rok: 2020, tom: 10, strony: 45305), Wydawca: Nature ResearchStatus:PublishedDOI:10.1038/s41598-020-68609-8 - link to the publication