Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Searching for behavioural and molecular predictors of long-term benzodiazepine administration in preclinical chronic stress model - the importance of individual differences.

2018/28/C/NZ7/00240

Keywords:

animal unpredictable chronic stress model benzodiazepines drug addiction mechanisms GABA-ergic system endogenous opioidergic system epigenetics microRNA individual differences

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Instytut Psychiatrii i Neurologii

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Karolina Kołosowska 

Number of co-investigators in the project: 5

Call: SONATINA 2 - announced on 2017-12-15

Amount awarded: 960 017 PLN

Project start date (Y-m-d): 2018-10-18

Project end date (Y-m-d): 2023-10-17

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. The effects of the recurrent social isolation stress on fear extinction and dopamine D2 receptors in the amygdala and the hippocampus.
    Authors:
    Wisłowska-Stanek A, Lehner M, Tomczuk F, Gawryluk A, Kołosowska K, Sułek A, Krząśnik P, Sobolewska A, Wawer A, Płaźnik A, Skórzewska A.
    Academic press:
    Pharmacol Rep. (rok: 2022, tom: 75(1), strony: 119-127), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s43440-022-00430-8 - link to the publication
  2. Molecular pattern of a decrease in the rewarding effect of cocaine after an escalating-dose drug regimen.
    Authors:
    Kołosowska K, Lehner M, Skórzewska A, Gawryluk A, Tomczuk F, Sobolewska A, Turzyńska D, Liguz-Lęcznar M, Bednarska-Makaruk M, Maciejak P, Wisłowska-Stanek A.
    Academic press:
    Pharmacol Rep. (rok: 2022, tom: 75(1), strony: 85-98), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s43440-022-00443-3 - link to the publication
  3. The role of the dorsal hippocampus in resistance to the development of posttraumatic stress disorder-like behaviours.
    Authors:
    Wisłowska-Stanek A, Lehner M, Tomczuk F, Kołosowska K, Krząśnik P, Turzyńska D, Skórzewska A.
    Academic press:
    Behavioural Brain Research (rok: 2022, tom: 438, strony: 114185), Wydawca: ScienceDirect
    Status:
    Published
    DOI:
    10.1016/j.bbr.2022.114185 - link to the publication
  4. microRNA-dependent regulation of gene expression in GABAergic interneurons
    Authors:
    Kołosowska KA, Schratt G, Winterer J.
    Academic press:
    Front Cell Neurosci. (rok: 2023, tom: 17, strony: 1188574), Wydawca: frontiers
    Status:
    Published
    DOI:
    10.3389/fncel.2023.1188574. - link to the publication