Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Role of membrane progesterone receptors in the regulation of endometrium activity

2017/27/B/NZ4/02973

Keywords:

membrane progesterone receptor PGRMC mPR intracellular signaliing proliferation secretion endometrium cow

Descriptors:

  • NZ4_6:
  • NZ4_2:

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Rozrodu Zwierząt i Badań Żywności PAN

woj. warmińsko-mazurskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Magdalena Karolina Kowalik 

Number of co-investigators in the project: 7

Call: OPUS 14 - announced on 2017-09-15

Amount awarded: 896 360 PLN

Project start date (Y-m-d): 2018-08-03

Project end date (Y-m-d): 2024-02-02

Project duration:: 66 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (2)
  1. Effect of steroid hormones, prostaglandins (E2 and F2α), oxytocin, and tumor necrosis factor alpha on membrane progesterone (P4) receptors gene expression in bovine myometrial cells
    Authors:
    Kowalik, Magdalena K.; Dobrzyń, Karolina; Młynarczuk, Jarosław; Rękawiecki, Robert
    Academic press:
    Animals (rok: 2022, tom: 12(4), strony: art. no 519 (1-13)), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ani12040519 - link to the publication
  2. Molekularny mechanizm działania progesteronu w żeńskim układzie rozrodczym [Molecular mechanism of progesterone action in the female reproductive system]
    Authors:
    Dobrzyń, Karolina; Kowalik, Magdalena K.
    Academic press:
    Postępy Biochemii / Advances in Biochemistry (rok: 2022, tom: 68(3), strony: 336-343), Wydawca: Polskie Towarzystwo Biochemiczne
    Status:
    Published
    DOI:
    10.18388/pb.2021_458 - link to the publication
  3. Expression of membrane progestin receptors (mPRs) α, β and γ in the bovine uterus during the oestrous cycle and pregnancy.
    Authors:
    Kowalik MK, Dobrzyń K, Rękawiecki R, Kotwica J.
    Academic press:
    Theriogenology (rok: 2019, tom: 140, strony: 171-179), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.theriogenology.2019.08.028 - link to the publication
  1. Transcriptome analysis of bovine endometrial endothelial cells with PGRMC2 silenced gene.
    Authors:
    Zajac P., Rękawiecki R., Myszczyński K., Panas D., Kaczmarek M.M., Kowalik MK.
    Conference:
    XXIX Congress of the Polish Physiological Society and the Federation of European Physiological Societies (rok: 2023, ), Wydawca: Polish Physiological Society
    Data:
    konferencja 21-23.09.2023
    Status:
    Published
  2. Membrane progestin receptor (mPR) δ and ε expression and localization throughout the estrous cycle in the bovine uterus abstract
    Authors:
    Kowalik M, Krajza K, Rekawieck R, Kotwica J.
    Conference:
    23rd Annual Conference of European Society for Domestic Animal Reproduction (ESDAR) (rok: 2019, ), Wydawca: Wiley Blackwell
    Data:
    konferencja 43727
    Status:
    Published

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