Projects funded by the NCN
Modulation of the structure and properties of curcumin using triterpene oleanolic modifiers
2017/27/N/NZ7/02423
Keywords:
curcumin oleanolic acid chemoprevention hybrid
Descriptors:
- NZ7_14: Pharmacy, pharmacotherapy, pharmacology
Panel:
NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution :
Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny
woj. wielkopolskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 14 - announced on 2017-09-15
Amount awarded: 139 540 PLN
Project start date (Y-m-d): 2018-09-03
Project end date (Y-m-d): 2022-09-02
Project duration:: 48 months (the same as in the proposal)
Project status: Project settled
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Equipment purchased [PL]
- Automatyczna komora do derywatyzacji dla płytek Camag Derivatizer (28 000 PLN)
- Waga laboratoryjna (5 000 PLN)
Information in the final report
- Publication in academic press/journals (3)
- Synthesis, Cytotoxicity and Molecular Docking of New Hybrid Compounds by Combination of Curcumin with Oleanolic AcidAuthors:Katarzyna Sowa-Kasprzak, Ewa Totoń, Jacek Kujawski, Dorota Olender, Natalia Lisiak, Lucjusz Zaprutko, Błażej Rubiś, Mariusz Kaczmarek, Anna PawełczykAcademic press:Biomedicines (rok: 2023, tom: 11(6), strony: 1506), Wydawca: MDPIStatus:PublishedDOI:10.3390/biomedicines11061506 - link to the publication
- Synthesis of curcumin derivatives containing non-steroidal anti-inflammatory drugsAuthors:Katarzyna Sowa-Kasprzak, Dorota Olender, Jacek Kujawski, Lucjusz Zaprutko, Anna PawełczykAcademic press:Acta Poloniae Pharmaceutica - Drug Research (rok: 2023, tom: Vol. 80 No. 2, strony: ), Wydawca: Polish Pharmaceutical SocietyStatus:Accepted for publicationDOI:10.32383/appdr/161972 - link to the publication
- Curcumin–Triterpene Type Hybrid as Effective Sonosensitizers for Sonodynamic Therapy in Oral Squamous Cell CarcinomaAuthors:Katarzyna Sowa-Kasprzak, Małgorzata Józkowiak, Dorota Olender, Anna Pawełczyk, Hanna Piotrowska-Kempisty, Lucjusz ZaprutkoAcademic press:Pharmaceutics (rok: 2023, tom: 15(7), strony: 2008), Wydawca: MDPIStatus:PublishedDOI:10.3390/pharmaceutics15072008 - link to the publication