Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Mitochondria transfer as an innovative method of restoring stemness of adipose-derived stem cells isolated from horses suffering from metabolic syndrome (EMS).

2017/27/N/NZ7/02343

Keywords:

mitochondria equine metabolic syndrome adipose-derived stem cells

Descriptors:

  • NZ7_13: Prevention of animal diseases

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Przyrodniczy we Wrocławiu, Wydział Biologii i Hodowli Zwierząt

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Katarzyna Kornicka-Garbowska 

Number of co-investigators in the project: 2

Call: PRELUDIUM 14 - announced on 2017-09-15

Amount awarded: 139 680 PLN

Project start date (Y-m-d): 2018-10-08

Project end date (Y-m-d): 2020-10-07

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Komputer stacjonarny (5 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  1. Mitochondrial transfer reverse aging of progenitor stem cells and enhance insulin sensitivity.
    Authors:
    Katarzyna Kornicka-Garbowska, Dale Moulding and Krzysztof Marycz
    Academic press:
    Stem Cell Reviews and Reports (rok: 2020, tom: nie dotyczy, strony: -), Wydawca: Springer Science+Business Media
    Status:
    Submitted
    DOI:
    brak - link to the publication
  2. MSI-1436 improves EMS adipose derived progenitor stem cells in the course of adipogenic differentiation through modulation of ER stress, apoptosis, and oxidative stress
    Authors:
    Bourebaba L, Kornicka-Garbowska K, Al Naem M, Röcken M, Siwinska N, Łyczko J, Marycz K
    Academic press:
    Stem Cell Research & Therapy (rok: 2021, tom: nie dotyczy, strony: 45309), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1186/s13287-020-02102-x - link to the publication
  3. Inhibition of protein tyrosine phosphatases improves mitochondrial bioenergetics and dynamics, reduces oxidative stress and enhance adipogenic differentiation potential in metabolically impaired progenitor stem cells.
    Authors:
    Katarzyna Kornicka-Garbowska,  Lynda Bourebaba ,  Michael Röcken,  Krzysztof Marycz
    Academic press:
    Oxidative Medicine and Cellular Longevity (rok: 2021, tom: nie dotyczy, strony: -), Wydawca: Springer Nature
    Status:
    Submitted
    DOI:
    brak - link to the publication

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