Inflammasome as skin cancerogenesis regulator- molecular and clinical study.

2017/27/B/NZ5/02011

Keywords

Descriptors

NZ5_3: Patogeneza chorób człowieka
NZ5_9: Inne zagadnienia pokrewne

Panel

NZ5 – Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Voivodeship: łódzkie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Aleksandra Ewa Lesiak

Number of co-investigators in the project: 6

Call

OPUS 14 – announced on 2017-09-15

Amount awarded: 959 180 PLN
Project start date: 2018-08-14
Project end date: 2024-06-13
Project duration: 70 months (the same as in the proposal)
Project status: Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (4)

Ultraviolet Radiation and Chronic Inflammation—Molecules and Mechanisms Involved in Skin Carcinogenesis: A Narrative Review

Authors:
Ciążyńska, M.; Olejniczak-Staruch, I.; Sobolewska-Sztychny, D.; Narbutt, J.; Skibińska, M.; Lesiak, A.

Academic press:
Life (year: 2021, volume: 11(4), pages: 326-340), Publisher: MDPI

Status:
Published

DOI:
10.3390/life11040326 – link to the publication
NLRP1 and NLRP3 inflammasomes as a new approach to skin carcinogenesis

Authors:
M. CIĄŻYŃSKA, I. BEDNARSKI, K. WÓDZ, J. NARBUTT, A. LESIAK

Academic press:
ONCOLOGY LETTERS (year: 2020, volume: 19, pages: 1649-1656), Publisher: Spandidos Publications

Status:
Published

DOI:
10.3892/ol.2020.11284 – link to the publication
New insight into the role of the pathway NLRP1 and NLRP3 inflammasomes and IL-33 in Ultraviolet-induced cutaneous carcinogenesis

Authors:
Aleksandra Lesiak, Karolina Wodz, Justyna Ceryn, Dorota Sobolewska –Sztychny, Igor Bednarski, Janusz Piekarski, Marta Pabianek, Dariusz Nejc, Izabela Dróżdż, Joanna Narbutt, Marcin Noweta, Magdalena Ciazynska

Academic press:
Frontiers in Medicine (year: 2025, volume: 11, pages: 46029), Publisher: Frontiers Media S.A.

Status:
Published

DOI:
10.3389/fmed.2024.1483208 – link to the publication
The role of inflammasomes in cutaneous pathology

Authors:
M. Ciążyńska, J. Narbutt, M. Skibińska, A. Lesiak

Academic press:
Advances in Dermatology and Allergology (year: 2022, volume: 1 vol. 39, pages: 39-46), Publisher: Termedia

Status:
Published

DOI:
10.5114/ada.2022.113802 – link to the publication

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