Projects funded by the NCN

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Information of the project and the call

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Inflammasome as skin cancerogenesis regulator- molecular and clinical study.

2017/27/B/NZ5/02011

Keywords:

inflammasome inflammation skin cancerogenesis

Descriptors:

  • NZ5_3: Pathogenesis of human diseases
  • NZ5_9: Other related subjects

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Aleksandra Lesiak 

Number of co-investigators in the project: 6

Call: OPUS 14 - announced on 2017-09-15

Amount awarded: 959 180 PLN

Project start date (Y-m-d): 2018-08-14

Project end date (Y-m-d): 2024-06-13

Project duration:: 36 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (12)
  1. Primary Merkel Cell Carcinoma: A Retrospective Analysis of 31 Cases in Poland
    Authors:
    Magdalena Ciazynska . Katarzyna Szczepaniak . Marta Pabianek . Dariusz Nejc . Adam Reich . Małgorzata Ułanska . Witold Owczarek . Małgorzata Skibinska . Joanna Narbutt . Aleksandra Lesiak
    Academic press:
    Dermatol Ther (Heidelb) (rok: 2020, tom: 10, strony: 1003-1012), Wydawca: Springer Link
    Status:
    Published
    DOI:
    10.1007/s13555-020-00424-5 - link to the publication
  2. The Role of NLRP1, NLRP3, and AIM2 Inflammasomes in Psoriasis: Review.
    Authors:
    Ciążyńska, M.; Olejniczak-Staruch, I.; Sobolewska-Sztychny, D.; Narbutt, J.; Skibińska, M.; Lesiak, A.
    Academic press:
    Int. J. Mol. Sci. (rok: 2021, tom: 22(11), strony: 5898-5909), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22115898 - link to the publication
  3. Itraconazole—A New Player in the Therapy of Advanced Basal Cell Carcinoma: A Case Report
    Authors:
    Magdalena Ciazynska, MD, PhD ; Joanna Narbutt, MD, PhD; Małgorzata Skibinska, MD, PhD ; and Aleksandra Lesiak, MD, PhD
    Academic press:
    JCO Oncology Practice (rok: 2020, tom: 16, strony: 837–838), Wydawca: American Society of Clinical Oncology
    Status:
    Published
    DOI:
    10.1200/ - link to the publication
  4. The incidence and clinical analysis of non‑melanoma skin cancer
    Authors:
    Magdalena Ciążyńska, Grażyna Kamińska-Winciorek, […]Aleksandra Lesiak
    Academic press:
    Nature Portfolio (rok: 2020, tom: 11, strony: 4337), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41598-021-83502-8 - link to the publication
  5. Ultraviolet Radiation and Chronic Inflammation—Molecules and Mechanisms Involved in Skin Carcinogenesis: A Narrative Review
    Authors:
    Ciążyńska, M.; Olejniczak-Staruch, I.; Sobolewska-Sztychny, D.; Narbutt, J.; Skibińska, M.; Lesiak, A.
    Academic press:
    Life (rok: 2021, tom: 11(4), strony: 326-340), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/life11040326 - link to the publication
  6. NLRP1 and NLRP3 inflammasomes as a new approach to skin carcinogenesis
    Authors:
    M. CIĄŻYŃSKA, I. BEDNARSKI, K. WÓDZ, J. NARBUTT, A. LESIAK
    Academic press:
    ONCOLOGY LETTERS (rok: 2020, tom: 19, strony: 1649-1656), Wydawca: Spandidos Publications
    Status:
    Published
    DOI:
    10.3892/ol.2020.11284 - link to the publication
  7. Promising Immune Treatment of Advanced Cutaneous Squamous Cell Carcinoma with Cemiplimab—Real-World Experience in the Global SARS-CoV-2 Pandemic
    Authors:
    Marta Pabianek, Aleksandra Lesiak, Dariusz Nejc, Łukasz Kuncman, Joanna Narbutt, Małgorzata Skibi ́nska and Magdalena Ci ̨a ̇zy ́nska
    Academic press:
    Current Oncology (rok: 2022, tom: 29, strony: 7794-7801), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/curroncol29100616 - link to the publication
  8. The incidence and clinical analysis of non-melanoma skin cancer
    Authors:
    Ciążyńska M, Kamińska-Winciorek G. Sławińska M, et al
    Academic press:
    Sci Rep (rok: 2021, tom: 11, strony: 4437-4447), Wydawca: Nature portfolio
    Status:
    Published
    DOI:
    10.1038/s41598-021-83502-8. - link to the publication
  9. The role of inflammasomes in cutaneous pathology
    Authors:
    M. Ciążyńska, J. Narbutt, M. Skibińska, A. Lesiak
    Academic press:
    Advances in Dermatology and Allergology (rok: 2022, tom: 1 vol. 39, strony: 39-46), Wydawca: Termedia
    Status:
    Published
    DOI:
    10.5114/ada.2022.113802 - link to the publication
  10. Clinical and epidemiological analysis of basosquamous carcinoma: results of the multicenter study
    Authors:
    Magdalena Ciążyńska*, Martyna Sławińska , Grażyna Kamińska‑Winciorek , Dariusz Lange , Bogumił Lewandowski, Adam Reich, Marta Pabianek, Katarzyna Szczepaniak Adam Hankiewicz, Małgorzata Ułańska, Jan Morawiec, Maria Błasińska‑Morawiec, Zbigniew Morawiec, Janusz Piekarski, Robert Brodowski, Anna Zaryczańska, Michał Sobjanek, Witold Owczarek, Monika Słowińska, Katarzyna Wróbel , Andrzej Bieniek, Anna Woźniacka, Małgorzata Skibińska, Joanna Narbutt, Wojciech Niemczyk, Karol Ciążyński & Aleksandra Lesiak
    Academic press:
    Nature Research (rok: 2020, tom: 10, strony: 18475), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41598-020-72732-x - link to the publication
  11. Quality of life of cancer patients during coronavirus disease (COVID-19) pandemic
    Authors:
    Magdalena Ciążynska 1 | Marta Pabianek1 | Katarzyna Szczepaniak1 | Małgorzata Ułanska 1 | Małgorzata Skibinska 2 | Witold Owczarek3 | Joanna Narbutt2 | Aleksandra Lesiak2
    Academic press:
    Psycho-Oncology (rok: 2020, tom: 29, strony: 45294), Wydawca: John Wiley & Sons, Ltd.
    Status:
    Published
    DOI:
    10.1002/pon.5434 - link to the publication
  12. Risk Factors and Clinicopathological Features for Developing a Subsequent Primary Cutaneous Squamous and Basal Cell Carcinomas
    Authors:
    Magdalena Ci ̨a ̇zy ́nska, Marta Pabianek, Martyna Sławi ́nska, Adam Reich, Bogumił Lewandowski, Katarzyna Szczepaniak, Małgorzata Uła ́nska, Dariusz Nejc, Robert Brodowski, Michał Sobjanek, Witold Owczarek, Gra ̇zyna Kami ́nska-Winciorek, Dariusz Lange, Monika Słowi ́nska , Katarzyna Wróbel, Andrzej Bieniek, Anna Wo ́zniacka, Anika P ̨ekala, Łukasz Kuncman, Magdalena Sali ́nska, Marcin Noweta, Małgorzata Skibi ́nska, Joanna Narbutt, Karol Ci ̨a ̇zy ́nski, Marta Lewandowska, El ̇zbieta Dziankowska-Zaborszczyk and Aleksandra Lesiak
    Academic press:
    Cancers (rok: 2022, tom: 14, strony: 3069), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers14133069 - link to the publication

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