Projects funded by the NCN
Vitamin D effects on macrophages and fibroblasts accompanying the breast cancer
2017/27/B/NZ5/01167
Keywords:
breast cancer macrophages fibroblasts TAMs CAFs vitamin D3 calcitriol
Descriptors:
- NZ5_7: Human disease treatment
- NZ5_3: Pathogenesis of human diseases
- NZ4_12: Other related subjects
Panel:
NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)
Host institution :
Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk
woj. dolnośląskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 17
Call: OPUS 14 - announced on 2017-09-15
Amount awarded: 1 716 680 PLN
Project start date (Y-m-d): 2018-09-26
Project end date (Y-m-d): 2022-09-25
Project duration:: 48 months (the same as in the proposal)
Project status: Project settled
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Equipment purchased [PL]
- Autoklaw.
- Termomikser.
- Mikroskop wyposażony w kamerę i oprogramowanie do analizy morfometrycznej obrazu. (70 000 PLN)
- Zamrażarka -80 (58211 PLN) oraz zamrażarka -20oC (1000PLN) (59 211 PLN)
Information in the final report
- Publication in academic press/journals (2)
- Modulation of fibroblast activity via vitamin D3 is dependent on tumor type—studies on mouse mammary gland cancerAuthors:Natalia Łabędź, Martyna Stachowicz-Suhs, Mateusz Psurski, Artur Anisiewicz, Joanna Banach, Aleksandra Piotrowska, Piotr Dziegiel, Adam Maciejczyk, Rafał Matkowski, Joanna WietrzykAcademic press:Cancers (rok: 2022, tom: 14, strony: 4585), Wydawca: MDPIStatus:PublishedDOI:10.3390/cancers14194585 - link to the publication
- Vitamin D Metabolite Profile in Cholecalciferol- or Calcitriol-Supplemented Healthy and Mammary Gland Tumor-Bearing MiceAuthors:Artur Anisiewicz, Konrad Kowalski, Joanna Banach, Natalia Łabędź, Martyna Stachowicz-Suhs, Aleksandra Piotrowska, Magdalena Milczarek, Dagmara Kłopotowska, Piotr Dzięgiel and Joanna WietrzykAcademic press:Nutrients (rok: 2020, tom: 12, strony: 3416), Wydawca: MDPIStatus:PublishedDOI:10.3390/nu12113416 - link to the publication