Raman spectroscopy in in studies on uptake of molecules by liver sinusoidal endothelial cells in vitro

2017/27/N/ST4/02867

Keywords

Descriptors

  • ST4_3: Metody spektroskopowe i spektrometryczne
  • ST4_13: Chemia fizyczna układów biologicznych

Panel

ST4 – Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Ewelina Krystyna Matuszyk

Number of co-investigators in the project: 2

Call

PRELUDIUM 14 – announced on 2017-09-15

Amount awarded
207 600 PLN
Project start date
2018-09-03
Project end date
2021-09-02
Project duration
36 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Dysk twardy przenośny. Cost: 400 PLN
  2. Komputer przenośny. Cost: 4 000 PLN
  3. Objektyw immersyjny. Cost: 30 000 PLN
  4. Optyczne, elektroniczne, mechaniczne elementy spektrometru (2 pcs). Cost: 14 937 PLN

Information in the final report

Publication in academic press/journals (2)

  1. Primary murine hepatocytes exposed to fatty acids analyzed by Raman and infrared microscopy

    Authors:
    Ewelina Matuszyk, Małgorzata Barańska
    Academic press:
    Journal of Clinical Spectroscopy (year: 2021, volume: 3, pages: 100007), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.clispe.2021.100007 – link to the publication
  2. Differential response of liver sinusoidal endothelial cells and hepatocytes to oleic and palmitic acid revealed by Raman and CARS imaging

    Authors:
    Ewelina Matuszyk, Ewa Sierka, Marko Rodewald, Hyeonsoo Bae, Tobias Meyer, Edyta Kus, Stefan Chlopicki, Michael Schmitt, Jürgen Popp, Malgorzata Baranska
    Academic press:
    Biochimica et Biophysica Acta - Molecular Basis of Disease (year: 2020, volume: 1866, pages: 165763), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbadis.2020.165763 – link to the publication

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Graphic design and implementation: Jakub Piotrowski