Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Raman spectroscopy in in studies on uptake of molecules by liver sinusoidal endothelial cells in vitro

2017/27/N/ST4/02867

Keywords:

Raman spectroscopy imaging cellular uptake chemometrics

Descriptors:

  • ST4_3: Molecular architecture and structure
  • ST4_13: Solid-state chemistry, surface physicochemistry

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Ewelina Matuszyk 

Number of co-investigators in the project: 2

Call: PRELUDIUM 14 - announced on 2017-09-15

Amount awarded: 207 600 PLN

Project start date (Y-m-d): 2018-09-03

Project end date (Y-m-d): 2021-09-02

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Objektyw immersyjny (30 000 PLN)
  2. Komputer przenośny (4 000 PLN)
  3. Dysk twardy przenośny (400 PLN)
  4. Optyczne, elektroniczne, mechaniczne elementy spektrometru (2 szt.) (14 937 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  1. Primary murine hepatocytes exposed to fatty acids analyzed by Raman and infrared microscopy
    Authors:
    Ewelina Matuszyk, Małgorzata Barańska
    Academic press:
    Journal of Clinical Spectroscopy (rok: 2021, tom: 3, strony: 100007), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.clispe.2021.100007 - link to the publication
  2. Differential response of liver sinusoidal endothelial cells and hepatocytes to oleic and palmitic acid revealed by Raman and CARS imaging
    Authors:
    Ewelina Matuszyk, Ewa Sierka, Marko Rodewald, Hyeonsoo Bae, Tobias Meyer, Edyta Kus, Stefan Chlopicki, Michael Schmitt, Jürgen Popp, Malgorzata Baranska
    Academic press:
    Biochimica et Biophysica Acta - Molecular Basis of Disease (rok: 2020, tom: 1866, strony: 165763), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbadis.2020.165763 - link to the publication

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