Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Molecular and clinical characteristics of keratin-based phenotypes in prostate cancer

2017/26/D/NZ5/01088

Keywords:

prostate cancer tumor progression basal and luminal keratins keratin-based keratins tumor progression circulating tumor cells metastases

Descriptors:

  • NZ4_5:
  • NZ3_1:
  • NZ5_5:

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Gdański Uniwersytet Medyczny, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Natalia Bednarz-Knoll 

Number of co-investigators in the project: 7

Call: SONATA 13 - announced on 2017-06-14

Amount awarded: 1 540 120 PLN

Project start date (Y-m-d): 2018-08-01

Project end date (Y-m-d): 2023-07-31

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (6)
  1. Low Tumor-to-Stroma Ratio Reflects Protective Role of Stroma against Prostate Cancer Progression
    Authors:
    Nastały P, Smentoch J, Popęda M, Martini E, Maiuri P, Żaczek AJ, Sowa M, Matuszewski M, Szade J, Kalinowski L, Niemira M, Brandt B, Eltze E, Semjonow A, Bednarz-Knoll N.
    Academic press:
    Journal of Personalized Medicine (rok: 2021, tom: 11, strony: 1088-1090), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/jpm11111088 - link to the publication
  2. EGFR as a stable marker of prostate cancer dissemination to bones.
    Authors:
    Nastały P, Stoupiec S, Popęda M, Smentoch J, Schlomm T, Morrissey C, Żaczek AJ, Beyer B, Tennstedt P, Graefen M, Eltze E, Maiuri P, Semjonow A, Pantel K, Brandt B, Bednarz-Knoll N.
    Academic press:
    British Journal of Cancer (rok: 2020, tom: 123(12), strony: 1767-1774), Wydawca: Nature Publishing Group (Wielka Brytania)
    Status:
    Published
    DOI:
    10.1038/s41416-020-01052-8 - link to the publication
  3. Emerin mislocalization during chromatin bridge resolution can drive prostate cancer cell invasiveness in a collagen-rich microenvironment
    Authors:
    Popęda M, Kowalski K, Wenta T, Beznoussenko GV, Rychłowski M, Mironov A, Lavagnino Z, Barozzi S, Richert J, Bertolio R, Myszczyński K, Szade J, Bieńkowski M, Miszewski K, Matuszewski M, Żaczek AJ, Braga L, Del Sal G, Bednarz-Knoll N, Maiuri P, Nastały P.
    Academic press:
    Experimetal and Molecular Medicine (rok: 2024, tom: 56, strony: 2016-2032), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s12276-024-01308-w - link to the publication
  4. Detection and characterization of circulating tumor cells using imaging flow cytometry – perspective
    Authors:
    Anna Muchlińska, Julia Smentoch, Anna Żaczek, Natalia Bednarz-Knoll
    Academic press:
    Cancers (Basel) (rok: 2022, tom: 14, strony: 4178), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers14174178 - link to the publication
  5. Expression patterns and co-repressor function of Retinoic Acid-induced 2 protein in progression of prostate cancer
    Authors:
    Katharina Besler, Aleksandra Weglarz, Laura Keller, Gunhild von Amsberg, Sara Stoupiec, Elke Eltze, Axel Semjonow, Natalia Bednarz-Knoll, Desirée Loreth, Lena Böttcher, Svenja Schneegans, Tobias Lange, Siegfried Hauch, Tilman Todenhoefer, Sven Peine, Klaus Pantel, Harriet Wikman, Stefan Werner
    Academic press:
    Clinical Chemistry (rok: 2022, tom: 68, strony: 973-983), Wydawca: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/clinchem/hvac073 - link to the publication
  6. Measurable morphological features of single circulating tumor cells in selected solid tumors-A pilot study
    Authors:
    Robert Wenta, Julia Richert, Anna Muchlińska, Elżbieta Senkus, Grażyna Suchodolska, Sylwia Łapińska-Szumczyk, Paweł Domżalski, Kevin Miszewski, Marcin Matuszewski, Rafał Dziadziuszko, Anna Supernat, Anna Żaczek , Natalia Bednarz-Knoll
    Academic press:
    Cytometry Part A (rok: 2024, tom: 105, strony: 883-892), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/cyto.a.24906 - link to the publication

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