Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The characteristic of the regulatory RNAs landscape in glioblastoma multiforme (GBM). Circular RNAs and micro RNA-like molecules as new players in gilomagenesis and GBM progression and their importance for glioblastoma stem cells

2017/26/E/NZ3/01004

Keywords:

regulatory RNA circular RNA sno-miRNA glioblastoma multiforme stem cells hallmarks of cancer mouse xenografts

Descriptors:

  • NZ1_1: Molecular biology
  • NZ2_2: Genomics, transcriptomics, epigenomics
  • NZ3_8: Stem cell biology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Katarzyna Rolle 

Number of co-investigators in the project: 10

Call: SONATA BIS 7 - announced on 2017-06-14

Amount awarded: 2 318 900 PLN

Project start date (Y-m-d): 2018-10-15

Project end date (Y-m-d): 2024-10-14

Project duration:: 48 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  1. miR-218 affects the ECM composition and cell biomechanical properties of glioblastoma cells
    Authors:
    Małgorzata Grabowska, Konrad Kuczyński, Monika Piwecka, Alicja Rabiasz, Joanna Zemła, Paweł Głodowicz, Dariusz Wawrzyniak, Małgorzata Lekka, Katarzyna Rolle
    Academic press:
    J Cell Mol Med. (rok: 2022, tom: 26, strony: 3913-3930), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/jcmm.17428 - link to the publication
  2. Non-Coding RNAs in Brain Tumors, the Contribution of lncRNAs, circRNAs, and snoRNAs to Cancer Development—Their Diagnostic and Therapeutic Potential
    Authors:
    Latowska Julia, Grabowska Adriana, Zarębska Żaneta, Kuczyński Konrad, Kuczyńska Bogna, Rolle Katarzyna
    Academic press:
    International Journal of Molecular Sciences (rok: 2020, tom: 21 (19), strony: 7001), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms21197001 - link to the publication