Projects funded by the NCN

Information on the principal investigator and host institution

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Biological activity of acylated anthocyanins and their interaction with mimetic lipid membrane and human albumin

2017/25/N/NZ9/02915

Keywords:

acylated anthocyanins antoxidant,ant-inflammatory and antitumor activities lipid mimetic membrane membrane fluidity,synergism with drugs

Descriptors:

  • NZ9_7:

Panel:

NZ9 - Fundamentals of applied life sciences and biotechnology: agricultural, forestry, horticulture, animal production and fishery, food and nutrition sciences, industrial biosciences, environmental biotechnology and remediation

Host institution :

Uniwersytet Przyrodniczy we Wrocławiu, Wydział Przyrodniczo-Technologiczny

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Paulina Anita Strugała-Danak 

Number of co-investigators in the project: 3

Call: PRELUDIUM 13 - announced on 2017-03-15

Amount awarded: 179 000 PLN

Project start date (Y-m-d): 2018-01-19

Project end date (Y-m-d): 2023-12-18

Project duration:: 71 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (7)
  1. A Comprehensive Study on the Biological Activity of Elderberry Extract and Cyanidin 3-O-Glucoside and Their Interactions with Membranes and Human Serum Albumin
    Authors:
    Paulina Strugała, Sabrina Loi , Barbara Bażanów, Piotr Kuropka, Alicja Z. Kucharska, Aleksandra Włoch, Janina Gabrielska
    Academic press:
    Molecules (rok: 2018, tom: 23, strony: 45679), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules23102566 - link to the publication
  2. Antitumor and antioxidant activities of purple potato ethanolic extract and its interaction with liposomes, albumin and plasmid DNA
    Authors:
    Paulina Strugała, Anna Urbaniak, Patryk Kuryś, Aleksandra Włoch, Teresa Kral, Maciej Ugorski, Martin Hof, Janina Gabrielska
    Academic press:
    Food & Function (rok: 2021, tom: 12, strony: 1271-1290), Wydawca: The Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/d0fo01667e - link to the publication
  3. Antidiabetic and Antioxidative Potential of the Blue Congo Variety of Purple Potato Extract in Streptozotocin-Induced Diabetic Rats
    Authors:
    Paulina Strugała, Olha Dzydzan, Iryna Brodyak, Alicja Z. Kucharska, Piotr Kuropka, Marianna Liuta, Katarzyna Kaleta-Kuratewicz, Agnieszka Przewodowska, Dorota Michałowska, Janina Gabrielska, Natalia Sybirna
    Academic press:
    Molecules (rok: 2019, tom: 24, strony: 45679), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules24173126 - link to the publication
  4. Analytical and Theoretical Studies of Antioxidant Properties of Chosen Anthocyanins; A Structure-Dependent Relationships
    Authors:
    Anita Dudek, Maciej Spiegel, Paulina Strugała-Danak, Janina Gabrielska
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23, strony: 45675), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms23105432 - link to the publication
  5. An analysis of interactions between three structurally diverse anthocyanidins, as well as their glucosides, and model biological membranes, albumin, and plasmid DNA
    Authors:
    Anita Dudek, Paulina Strugała‑Danak, Teresa Kral, Martin Hof, Hanna Pruchnik
    Academic press:
    Scientific Reports (rok: 2023, tom: 13, strony: 45670), Wydawca: Nature
    Status:
    Published
    DOI:
    10.1038/s41598-023-39470-2 - link to the publication
  6. Malvidin and Its Mono- and Di-Glucosides Forms: A Study of Combining Both In Vitro and Molecular Docking Studies Focused on Cholinesterase, Butyrylcholinesterase, COX-1 and COX-2 Activities
    Authors:
    Paulina Strugała-Danak, Maciej Spiegel, Janina Gabrielska
    Academic press:
    Molecules (rok: 2023, tom: 28, strony: 45671), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules28237872 - link to the publication
  7. Interference of malvidin and its mono- and di-glucosides on the membrane — Combined in vitro and computational chemistry study
    Authors:
    Paulina Strugała-Danak, Maciej Spiegel, Kacper Hurynowicz, Janina Gabrielska
    Academic press:
    Journal of Functional Foods (rok: 2022, tom: 99, strony: 45670), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jff.2022.105340 - link to the publication

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