Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Phthalimide derivatives of porphyrazines incorporated into liposomes as potential candidates for photodynamic therapy

2017/25/N/NZ7/01705

Keywords:

phthalimide photodynamic therapy porphyrazine synthesis liposomes

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, Wydział Farmaceutyczny

woj. kujawsko-pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Michał Falkowski 

Number of co-investigators in the project: 2

Call: PRELUDIUM 13 - announced on 2017-03-15

Amount awarded: 180 000 PLN

Project start date (Y-m-d): 2018-01-25

Project end date (Y-m-d): 2023-01-24

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Pompa próżniowa V-100 z kontrolerem próżni I-100 firmy BÜCHI (12 300 PLN)
  2. Termostat cyrkulacyjny Minichiller w firmy Huber (15 500 PLN)
  3. Mieszadło magnetyczne firmy Heidolph wraz z nakładkami Heat-on (5 800 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (6)
  1. Synthesis of sulfanyl porphyrazines with bulky peripheral substituents – Evaluation of their photochemical properties and biological activity
    Authors:
    Michal Falkowski, Malgorzata Kucinska, Jarosław Piskorz, Ewelina Wieczorek-Szweda, Lukasz Popenda, Stefan Jurga, Adam Sikora, Dariusz T. Młynarczyk, Marek Murias, Michal P. Marszall, Tomasz Goslinski
    Academic press:
    Journal of Photochemistry and Photobiology A: Chemistry (rok: 2021, tom: 405, strony: 112964), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jphotochem.2020.112964 - link to the publication
  2. A synergistic effect of phthalimide-substituted sulfanyl porphyrazines and carbon nanotubes to improve the electrocatalytic detection of hydrogen peroxide
    Authors:
    Michal Falkowski, Amanda Leda, Tomasz Rebis, Jaroslaw Piskorz, Lukasz Popenda, Mina Hassani, Dariusz T Mlynarczyk, Michal P Marszall, Grzegorz Milczarek
    Academic press:
    Molecules (rok: 2022, tom: 27, 4409, strony: 45306), Wydawca: MDPI
    Status:
    Published
    DOI:
    https://www.mdpi.com/1420-3049/27/14/4409 - link to the publication
  3. Improved Electrochemical Hydrogen Peroxide Detection Using a Nickel(II) Phthalimide-Substituted Porphyrazine Combined with Various Carbon Nanomaterials
    Authors:
    Amanda Leda, Mina Hassani, Tomasz Rebis, Michal Falkowski, Jaroslaw Piskorz, Dariusz T Mlynarczyk, Peter McNeice, Grzegorz Milczarek
    Academic press:
    Nanomaterials (rok: 2023, tom: 13, 862, strony: 45305), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/nano13050862 - link to the publication
  1. Synergiczny efekt porfirazyn siarkowych posiadających peryferyjne ugrupowanie ftamimidowe i nanorurek węglowych w celu poprawy elektrokatalitycznego wykrywania nadtlenku wodoru
    Authors:
    Mina Hassani, Amanda Leda, Michal Falkowski, Weronika Porolnik, Tomasz Rebis, Michal P. Marszall, Grzegorz Milczarek
    Conference:
    BioOrg - IV Ogólnopolskie Sympozjum Chemii Bioorganicznej, Organicznej i Biomateriałów (rok: 2022, ), Wydawca: Wydział Technologii Chemicznej Politechniki Poznańskiej
    Data:
    konferencja 3 grudnia
    Status:
    Published
  2. Synthesis and optical properties of sulfanyl porphyrazines possessing phthalimide substituents in the periphery
    Authors:
    Michal Falkowski, Jaroslaw Piskorz, Ewelina Wieczorek, Adam Sikora, Dominik Mieszkowski, Dariusz T Mlynarczyk, Lukasz Popenda, Jadwiga Mielcarek, Tomasz Goslinski, Michal P. Marszall
    Conference:
    Annual Congress of the Italian Society of Photobiology – SIFB2019 (rok: 2019, ), Wydawca: Italian National Research Council, Bologna Institute of Organic Synthesis & Photoreactivity (ISOF)
    Data:
    konferencja 19-21 Czerwiec
    Status:
    Published
  3. Sulfanyl porphyrazines with bulky phthalimide substituents, synthesis, optical and electrochemical properties
    Authors:
    Mina Hassani, Michal Falkowski, Amanda Leda, Tomasz Rebis, Weronika Porolnik, Sandra Gajewska, Natalia Kocot, Michal P. Marszall
    Conference:
    XXVII EFMC International Symposium on Medicinal Chemistry (rok: 2022, ), Wydawca: Société de Chimie Thérapeutique (SCT)
    Data:
    konferencja 4-8 września 2022
    Status:
    Published
  4. Synthesis of sylfanyl porphyrazines with bulky phthalimide subtituents in the periphery. Synergic effect with nanostructural components for catalytical properties
    Authors:
    Michal Falkowski, Tomasz Rebis, Lukasz Popenda, Jaroslaw Piskorz, Jacek Dulęba, Joanna Chałupka, Grzegorz Milczarek, Michal P. Marszall
    Conference:
    18th Blue Danube Symposium on Heterocyclic Chemistry (rok: 2019, ), Wydawca: University of Ljubljana, Faculty of Chemistry and Chemical Technology
    Data:
    konferencja 18-21 Wrzesień
    Status:
    Published
  5. Synthesis of phthalimide sulfanyl porphyrazines and their optical properties
    Authors:
    Michal Falkowski, Lukasz Popenda, Jaroslaw Piskorz, Ewelina Wieczorek, Stefan Jurga, Michal P. Marszall, Dominik Mieszkowski, Jadwiga Mielcarek, Tomasz Goslinski
    Conference:
    NanoTech Poland & 1st Symposium on Polydopamine (rok: 2018, ), Wydawca: NanoBioMedical Centre, Adam Mickiewicz University in Poznan
    Data:
    konferencja 6-9 czerwca
    Status:
    Published
  6. A Metallated sulfanyl porphyrazines possessing phthalimid substituents – electrochemical properties and synergic effect with nanomaterial components
    Authors:
    Michal Falkowski, Lukasz Popenda, Tomasz Rebis, Jaroslaw Piskorz, Dariusz T. Mlynarczyk, Stefan Jurga, Michal P. Marszall, Adam Sikora, Jadwiga Mielcarek, Grzegorz Milczarek, Tomasz Goslinski
    Conference:
    NanoTech Poland & 1st Symposium on Polydopamine (rok: 2018, ), Wydawca: NanoBioMedical Centre, Adam Mickiewicz University in Poznan
    Data:
    konferencja 6-9 czerwca
    Status:
    Published

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