Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Evaluation of tumor vasculature normalisation on effectiveness of the therapeutic melanoma vaccines in mice models

2016/23/B/NZ6/02542

Keywords:

melanoma microenvironment vasculature murine model

Descriptors:

  • NZ6_8: Other related subjects
  • NZ6_1: Adaptive and innate immunity

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Andrzej Mackiewicz 

Number of co-investigators in the project: 6

Call: OPUS 12 - announced on 2016-09-15

Amount awarded: 1 300 390 PLN

Project start date (Y-m-d): 2017-07-18

Project end date (Y-m-d): 2022-07-17

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. oprogramowanie FlowJo 10 (13 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  1. Oxygen therapeutic window induced by myo-inositol trispyrophosphate (ITPP) – local pO 2 study in murine tumors
    Authors:
    Martyna Krzykawska-Serda , Dariusz Szczygieł , Szymon Gaweł , Agnieszka Drzał , Małgorzata Szczygieł , Maciej M Kmieć , Andrzej Mackiewicz , Claudine Kieda , Martyna Elas
    Academic press:
    PLOS ONE (rok: 2023, tom: 18(5), strony: e0285318), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pone.0285318 - link to the publication
  2. Tumour angiogenesis normalized by myo-inositol trispyrophosphate alleviates hypoxia in the microenvironment and promotes antitumor immune response
    Authors:
    Bouchra E, Hafny-Rahbi, Klaudia Brodaczewska, Guillaume Collet, Aleksandra Majewska, Krzysztof Klimkiewicz, Anthony Delalande, Catherine Grillon, Claudine Kieda
    Academic press:
    J Cell Mol Med (rok: 2021, tom: 25(7), strony: 3284-3299), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/jcmm.16399 - link to the publication

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