Evaluation of tumor vasculature normalisation on effectiveness of the therapeutic melanoma vaccines in mice models

2016/23/B/NZ6/02542

Keywords

Descriptors

  • NZ6_8: Inne zagadnienia pokrewne
  • NZ6_1: Odporność swoista i nieswoista

Panel

NZ6 – Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

Voivodeship: wielkopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Andrzej Mackiewicz

Number of co-investigators in the project: 6

Call

OPUS 12 – announced on 2016-09-15

Amount awarded
1 300 390 PLN
Project start date
2017-07-18
Project end date
2022-07-17
Project duration
60 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. oprogramowanie FlowJo 10. Cost: 13 000 PLN

Information in the final report

Publication in academic press/journals (2)

  1. Oxygen therapeutic window induced by myo-inositol trispyrophosphate (ITPP) – local pO 2 study in murine tumors

    Authors:
    Martyna Krzykawska-Serda , Dariusz Szczygieł , Szymon Gaweł , Agnieszka Drzał , Małgorzata Szczygieł , Maciej M Kmieć , Andrzej Mackiewicz , Claudine Kieda , Martyna Elas
    Academic press:
    PLOS ONE (year: 2023, volume: 18(5), pages: e0285318), Publisher: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pone.0285318 – link to the publication
  2. Tumour angiogenesis normalized by myo-inositol trispyrophosphate alleviates hypoxia in the microenvironment and promotes antitumor immune response

    Authors:
    Bouchra E, Hafny-Rahbi, Klaudia Brodaczewska, Guillaume Collet, Aleksandra Majewska, Krzysztof Klimkiewicz, Anthony Delalande, Catherine Grillon, Claudine Kieda
    Academic press:
    J Cell Mol Med (year: 2021, volume: 25(7), pages: 3284-3299), Publisher: Wiley
    Status:
    Published
    DOI:
    10.1111/jcmm.16399 – link to the publication

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