Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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LDI MS and MSI in search of new renal cancer biomarkers

2016/23/B/ST4/00062

Keywords:

mass spectrometry mass spectrometry imaging cancer biomarkers

Descriptors:

  • ST4_3: Molecular architecture and structure
  • ST4_8: Organic chemistry

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Politechnika Rzeszowska im. Ignacego Łukasiewicza, Wydział Chemiczny

woj. podkarpackie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Tomasz Ruman 

Number of co-investigators in the project: 11

Call: OPUS 12 - announced on 2016-09-15

Amount awarded: 618 540 PLN

Project start date (Y-m-d): 2017-07-10

Project end date (Y-m-d): 2020-12-09

Project duration:: 41 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (10)
  1. Laser desorption/ionization MS imaging of cancer kidney tissue on silver nanoparticle-enhanced target
    Authors:
    Adrian Arendowski, Joanna Nizioł, Krzysztof Ossoliński, Anna Ossolińska, Tadeusz Ossoliński, Zygmunt Dobrowolski & Tomasz Ruman
    Academic press:
    Bioanalysis (rok: 2017, tom: 10, strony: 83-94), Wydawca: Future Science
    Status:
    Published
    DOI:
    10.4155/bio-2017-0195 - link to the publication
  2. Localization of metabolites of human kidney tissue with infrared laser-based selected reaction monitoring mass spectrometry imaging and silver-109 nanoparticle-based surface assisted laser desorption/ionization mass spectrometry imaging
    Authors:
    J. Niziol, J. Sunner, I. Beech, K. Ossoliński, A. Ossolińska, T. Ossoliński, A. Płaza and T. Ruman
    Academic press:
    Anal. Chem. (rok: 2020, tom: 92(6), strony: 4251-4258), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.analchem.9b04580 - link to the publication
  3. Mass spectrometry imaging of low molecular weight metabolites in strawberry fruit (Fragaria x ananassa Duch.) cv. Primoris with 109Ag nanoparticle enhanced target
    Authors:
    M. Misiorek, J. Niziol, T. Ruman
    Academic press:
    Phytochemistry (rok: 2019, tom: 159, strony: 45615), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.phytochem.2018.11.014 - link to the publication
  4. Metabolomic study of human tissue and urine in clear cell renal carcinoma by LC-HRMS and PLS-DA
    Authors:
    J. Nizioł, V. Bonifay, K. Ossoliński, T. Ossoliński, A. Ossolińska, J. Sunner, I. Beech, A. Arendowski and T. Ruman
    Academic press:
    Analytical and Bioanalytical Chemistry (rok: 2018, tom: 410, strony: 3859–3869), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00216-018-1059-x - link to the publication
  5. Silver‐109‐based laser desorption/ionization mass spectrometry method for detection and quantification of amino acids
    Authors:
    Adrian Arendowski | Joanna Nizioł | Tomasz Ruman
    Academic press:
    Journal of Mass Spectrometry (rok: 2018, tom: 53, strony: 369-378), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/jms.4068 - link to the publication
  6. Nuclear magnetic resonance and surface-assisted laser desorption/ionization mass spectrometry-based metabolome profiling of urine samples from kidney cancer patients
    Authors:
    Nizioł, J., Ossoliński, K., Tripet, B.P., Copié, V., Arendowski, A., Ruman, T.
    Academic press:
    Journal of Pharmaceutical and Biomedical Analysis (rok: 2021, tom: 193, strony: 113752), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jpba.2020.113752 - link to the publication
  7. Nuclear magnetic resonance and surface-assisted laser desorption/ionization mass spectrometry-based serum metabolomics of kidney cancer
    Authors:
    Nizioł, J., Ossoliński, K., Tripet, B.P., Copie, V., Arendowski, A., Ruman, T
    Academic press:
    Analytical and Bioanalytical Chemistry (rok: 2020, tom: 412(23), strony: 5827-5841), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00216-020-02807-1 - link to the publication
  8. Metabolomic and elemental profiling of human tissue in kidney cancer
    Authors:
    Joanna Nizioł, Valérie Copié, Brian P. Tripet, Leonardo B. Nogueira, Katiane O.P.C. Nogueira, Krzysztof Ossoliński, Adrian Arendowski and Tomasz Ruman
    Academic press:
    Metabolomics (rok: 2021, tom: -, strony: -), Wydawca: Springer
    Status:
    Accepted for publication
    DOI:
    brak - link to the publication
  9. Gold and silver nanoparticles‐based laser desorption/ionization mass spectrometry method for detection and quantification of carboxylic acids
    Authors:
    Artur Kołodziej, Tomasz Ruman, Joanna Nizioł
    Academic press:
    Journal of Mass Spectrometry (rok: 2020, tom: 55(10), strony: e4604), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/jms.4604 - link to the publication
  10. Laser Ablation Remote-Electrospray Ionisation Mass Spectrometry (LARESI MSI) Imaging—New Method for Detection and Spatial Localization of Metabolites and Mycotoxins Produced by Moulds
    Authors:
    Justyna Szulc, Tomasz Ruman
    Academic press:
    Toxins (rok: 2020, tom: 12(11), strony: 720), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/toxins12110720 - link to the publication

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