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The mechanism of the microRNA-dependent regulation of the invasiveness in the human pituitary adenomas.

2016/23/N/NZ5/02597

Keywords

Descriptors

  • NZ5_3: Patogeneza chorób człowieka
  • NZ5_5: Diagnostyka chorób człowieka
  • NZ4_8: Neuroendokrynologia

Panel

NZ5 – Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution

Warszawski Uniwersytet Medyczny

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Beata Krystyna Rak-Makowska

Number of co-investigators in the project: 2

Call

PRELUDIUM 12 – announced on 2016-09-15

Amount awarded
149 998 PLN
Project start date
2017-09-12
Project end date
2024-10-11
Project duration
85 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (6)

  1. Retrospective analysis of 348 surgeries due to Cushing's disease. The granulation pattern and immediate remission status.

    Authors:
    Beata Rak, Maria Maksymowicz, Monika Pękul, Grzegorz Zieliński
    Academic press:
    Frontiers in Endocrinology (year: 2021, volume: 12:672178, pages: 46031), Publisher: Frontiers
    Status:
    Published
    DOI:
    10.3389/fendo.2021.672178 – link to the publication

  2. MicroRNA signatures of invasiveness in PitNETs: a focus on miR-186-5p, miR-191-5p, miR-454-3p, and miR-590-5p

    Authors:
    Beata Rak-Makowska, Filip Garbicz, Dawid Mehlich, Emir Sajjad, Zofia Kuśmierczyk, Grzegorz Zieliński, Maria Maksymowicz, Sabrina Doboszek, Tomasz M Grzywa, Paweł Włodarski, Dominika Nowis, Urszula Ambroziak
    Academic press:
    Endocrine (year: 2025, volume: Published 06 October 2025, pages: article online- ahead of print.), Publisher: Springer nature
    Status:
    Published
    DOI:
    10.1007/s12020-025-04435-0 – link to the publication

  3. Lineage-dependent Role of miR-410-3p as oncomiR in Gonadotroph and Corticotroph Pituitary Adenomas or Tumor Suppressor miR in Somatotroph Adenomas via MAPK, PTEN/AKT, and STAT3 Signaling Pathways

    Authors:
    Tomasz M Grzywa , Klaudia Klicka, Beata Rak (autor korespondencyjny), Dawid Mehlich, Filip Garbicz, Grzegorz Zieliński, Maria Maksymowicz, Emir Sajjad, Paweł K Włodarski
    Academic press:
    Endocrine (year: 2019, volume: 65 (3), pages: 646 - 655), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/s12020-019-01960-7 – link to the publication

  4. The role of microRNAs in epithelial to mesenchymal transition and cancers; focusing on mir-200 family

    Authors:
    Ignacy Górecki, Beata Rak
    Academic press:
    Cancer Treatment and Research Communications (year: 2021, volume: 28, pages: 46031), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ctarc.2021.100385 – link to the publication

  5. Pituitary tumors - a large retrospective single-center study of over 2300 cases. An experience of tertiary reference center.

    Authors:
    Beata Rak, Maria Maksymowicz, Tomasz M Grzywa, Emir Sajjad, Monika Pękul, Paweł Włodarski, Grzegorz Zieliński
    Academic press:
    Endokrynologia Polska (year: 2020, volume: nie nadano, pages: obecnie nadano jedynie DOI), Publisher: Via Medica Journals
    Status:
    Published
    DOI:
    10.5603/EP.a2020.0011 – link to the publication

  6. The regulation of cyclin D promoters – review

    Authors:
    Jan Pawlonka , Beata Rak , Urszula Ambroziak
    Academic press:
    Cancer Treatment and Research Communications (year: 2021, volume: 27, pages: 46032), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ctarc.2021.100338 – link to the publication

Articles in post-conference publications (1)

  1. The Mechanism Of The Microrna-dependent Regulation Of The Invasiveness In Pituitary Adenomas

    Authors:
    Beata Rak,Tomasz M. Grzywa, Filip Garbicz, Dawid Mehlich, Zofia Kusmierczyk, Sabrina Dobroszek, Maria Maksymowicz, Emir Sajjad, Grzegorz Zieliński, Paweł K. Włodarski.
    Conference:
    ENDO 2018 (year: 2018, pages: Presentation Number: SUN-628-LB), Publisher: Endocrine Reviews, Volume 39, Issue 2 Supplement, April 2018
    Date:
    conference 15-20.03.2018
    Status:
    Published

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