Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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The mechanism of the microRNA-dependent regulation of the invasiveness in the human pituitary adenomas.

2016/23/N/NZ5/02597

Keywords:

gruczolak przysadki microRNA miR NGS Sekwencjonowanie Nowej Generacji

Descriptors:

  • NZ5_3: Pathogenesis of human diseases
  • NZ5_5: Diagnostics in human diseases
  • NZ4_8: Neuroendocrinology

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Warszawski Uniwersytet Medyczny, Wydzial Lekarski

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Beata Rak-Makowska 

Number of co-investigators in the project: 2

Call: PRELUDIUM 12 - announced on 2016-09-15

Amount awarded: 149 998 PLN

Project start date (Y-m-d): 2017-09-12

Project end date (Y-m-d): 2024-10-11

Project duration:: 36 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (6)
  • Articles in post-conference publications (1)
  1. Lineage-dependent Role of miR-410-3p as oncomiR in Gonadotroph and Corticotroph Pituitary Adenomas or Tumor Suppressor miR in Somatotroph Adenomas via MAPK, PTEN/AKT, and STAT3 Signaling Pathways
    Authors:
    Tomasz M Grzywa , Klaudia Klicka, Beata Rak (autor korespondencyjny), Dawid Mehlich, Filip Garbicz, Grzegorz Zieliński, Maria Maksymowicz, Emir Sajjad, Paweł K Włodarski
    Academic press:
    Endocrine (rok: 2019, tom: 65 (3), strony: 646 - 655), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12020-019-01960-7 - link to the publication
  2. Pituitary tumors - a large retrospective single-center study of over 2300 cases. An experience of tertiary reference center.
    Authors:
    Beata Rak, Maria Maksymowicz, Tomasz M Grzywa, Emir Sajjad, Monika Pękul, Paweł Włodarski, Grzegorz Zieliński
    Academic press:
    Endokrynologia Polska (rok: 2020, tom: nie nadano, strony: obecnie nadano jedynie DOI), Wydawca: Via Medica Journals
    Status:
    Published
    DOI:
    10.5603/EP.a2020.0011 - link to the publication
  3. The regulation of cyclin D promoters – review
    Authors:
    Jan Pawlonka , Beata Rak , Urszula Ambroziak
    Academic press:
    Cancer Treatment and Research Communications (rok: 2021, tom: 27, strony: 45301), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ctarc.2021.100338 - link to the publication
  4. Retrospective analysis of 348 surgeries due to Cushing's disease. The granulation pattern and immediate remission status.
    Authors:
    Beata Rak, Maria Maksymowicz, Monika Pękul, Grzegorz Zieliński
    Academic press:
    Frontiers in Endocrinology (rok: 2021, tom: 12:672178, strony: 45300), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fendo.2021.672178 - link to the publication
  5. The role of microRNAs in epithelial to mesenchymal transition and cancers; focusing on mir-200 family
    Authors:
    Ignacy Górecki, Beata Rak
    Academic press:
    Cancer Treatment and Research Communications (rok: 2021, tom: 28, strony: 45300), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ctarc.2021.100385 - link to the publication
  6. The importance of miR186-5p, miR-191-5p, miR-454-3p, and miR-590-5p for the PitNETs' invasiveness, and their correlation of coexpression with PTEN, TGFβ1, and TIMP-2 genes.
    Authors:
    Beata Rak-Makowska1,2 MD PhD , Filip Garbicz3 MD PhD, Dawid Mehlich MD PhD, Emir Sajjad4 MD PhD, Zofia Domosud, Grzegorz Zieliński MD PhD4, Maria Maksymowicz PhD5, Sabrina Doboszek, Tomasz Grzywa MD PhD, Paweł Włodarski MD PhD, Dominika Nowis2,3 MD PhD, Urszula Ambroziak1 MD PhD
    Academic press:
    brak (rok: 2024, tom: brak, strony: brak), Wydawca: brak
    Status:
    Submitted
    DOI:
    brak - link to the publication
  1. The Mechanism Of The Microrna-dependent Regulation Of The Invasiveness In Pituitary Adenomas
    Authors:
    Beata Rak,Tomasz M. Grzywa, Filip Garbicz, Dawid Mehlich, Zofia Kusmierczyk, Sabrina Dobroszek, Maria Maksymowicz, Emir Sajjad, Grzegorz Zieliński, Paweł K. Włodarski.
    Conference:
    ENDO 2018 (rok: 2018, ), Wydawca: Endocrine Reviews, Volume 39, Issue 2 Supplement, April 2018
    Data:
    konferencja 15-20.03.2018
    Status:
    Published

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