Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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The mechanism of the microRNA-dependent regulation of the invasiveness in the human pituitary adenomas.

2016/23/N/NZ5/02597

Keywords:

gruczolak przysadki microRNA miR NGS Sekwencjonowanie Nowej Generacji

Descriptors:

  • NZ5_3:
  • NZ5_5:
  • NZ4_8:

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Warszawski Uniwersytet Medyczny

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Beata Krystyna Rak-Makowska 

Number of co-investigators in the project: 2

Call: PRELUDIUM 12 - announced on 2016-09-15

Amount awarded: 149 998 PLN

Project start date (Y-m-d): 2017-09-12

Project end date (Y-m-d): 2024-10-11

Project duration:: 85 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (6)
  • Articles in post-conference publications (1)
  1. MicroRNA signatures of invasiveness in PitNETs: a focus on miR-186-5p, miR-191-5p, miR-454-3p, and miR-590-5p
    Authors:
    Beata Rak-Makowska, Filip Garbicz, Dawid Mehlich, Emir Sajjad, Zofia Kuśmierczyk, Grzegorz Zieliński, Maria Maksymowicz, Sabrina Doboszek, Tomasz M Grzywa, Paweł Włodarski, Dominika Nowis, Urszula Ambroziak
    Academic press:
    Endocrine (rok: 2025, tom: Published 06 October 2025, strony: article online- ahead of print.), Wydawca: Springer nature
    Status:
    Published
    DOI:
    10.1007/s12020-025-04435-0 - link to the publication
  2. Retrospective analysis of 348 surgeries due to Cushing's disease. The granulation pattern and immediate remission status.
    Authors:
    Beata Rak, Maria Maksymowicz, Monika Pękul, Grzegorz Zieliński
    Academic press:
    Frontiers in Endocrinology (rok: 2021, tom: 12:672178, strony: 46031), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fendo.2021.672178 - link to the publication
  3. Lineage-dependent Role of miR-410-3p as oncomiR in Gonadotroph and Corticotroph Pituitary Adenomas or Tumor Suppressor miR in Somatotroph Adenomas via MAPK, PTEN/AKT, and STAT3 Signaling Pathways
    Authors:
    Tomasz M Grzywa , Klaudia Klicka, Beata Rak (autor korespondencyjny), Dawid Mehlich, Filip Garbicz, Grzegorz Zieliński, Maria Maksymowicz, Emir Sajjad, Paweł K Włodarski
    Academic press:
    Endocrine (rok: 2019, tom: 65 (3), strony: 646 - 655), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12020-019-01960-7 - link to the publication
  4. The role of microRNAs in epithelial to mesenchymal transition and cancers; focusing on mir-200 family
    Authors:
    Ignacy Górecki, Beata Rak
    Academic press:
    Cancer Treatment and Research Communications (rok: 2021, tom: 28, strony: 46031), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ctarc.2021.100385 - link to the publication
  5. Pituitary tumors - a large retrospective single-center study of over 2300 cases. An experience of tertiary reference center.
    Authors:
    Beata Rak, Maria Maksymowicz, Tomasz M Grzywa, Emir Sajjad, Monika Pękul, Paweł Włodarski, Grzegorz Zieliński
    Academic press:
    Endokrynologia Polska (rok: 2020, tom: nie nadano, strony: obecnie nadano jedynie DOI), Wydawca: Via Medica Journals
    Status:
    Published
    DOI:
    10.5603/EP.a2020.0011 - link to the publication
  6. The regulation of cyclin D promoters – review
    Authors:
    Jan Pawlonka , Beata Rak , Urszula Ambroziak
    Academic press:
    Cancer Treatment and Research Communications (rok: 2021, tom: 27, strony: 46032), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ctarc.2021.100338 - link to the publication
  1. The Mechanism Of The Microrna-dependent Regulation Of The Invasiveness In Pituitary Adenomas
    Authors:
    Beata Rak,Tomasz M. Grzywa, Filip Garbicz, Dawid Mehlich, Zofia Kusmierczyk, Sabrina Dobroszek, Maria Maksymowicz, Emir Sajjad, Grzegorz Zieliński, Paweł K. Włodarski.
    Conference:
    ENDO 2018 (rok: 2018, ), Wydawca: Endocrine Reviews, Volume 39, Issue 2 Supplement, April 2018
    Data:
    konferencja 15-20.03.2018
    Status:
    Published

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