Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The neural circuitry underlying the generation of high frequency oscillations (HFO) in olfactory brain regions in a rat model of schizophrenia

2016/23/B/NZ4/03657

Keywords:

rat model of schizophrenia olfactory brain regions high frequency oscillations

Descriptors:

  • NZ4_7: Neurophysiology
  • NZ4_4: Pathophysiology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Biologii Doświadczalnej im. M. Nenckiego Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Mark Hunt 

Number of co-investigators in the project: 4

Call: OPUS 12 - announced on 2016-09-15

Amount awarded: 882 000 PLN

Project start date (Y-m-d): 2017-09-13

Project end date (Y-m-d): 2022-09-12

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. 44 kanałowy komutator (Crist Instruments) (28 000 PLN)
  2. 32 kanałowy wzmacniacz (Neuronexus) (127 500 PLN)
  3. AM-Systems 16 Channel Amplifier (56 700 PLN)
  4. Pompa do podwójnej iniekcji, np. Harvard Pump 22 Syringe Pump (14 000 PLN)
  5. System do kontrolowania i utrzymywania stałej temperatury ciala gryzoni.

Information in the final report

  • Publication in academic press/journals (4)
  1. Nasal respiration is necessary for ketamine-dependent high frequency network oscillations and behavioral hyperactivity in rats
    Authors:
    Wróbel J, Średniawa W, Jurkiewicz G, Żygierewicz J, Wójcik DK, Whittington MA, Hunt MJ
    Academic press:
    Scientific Reports (rok: 2020, tom: 10, strony: online/ nr artykułu 18981), Wydawca: Nature
    Status:
    Published
    DOI:
    10.1038/s41598-020-75641-1 - link to the publication
  2. Addressing pitfalls in phase-amplitude coupling analysis with an extended Modulation Index toolbox
    Authors:
    Gabriela Justyna Jurkiewicz, Mark Jeremy Hunt, Jarosław Żygierewicz
    Academic press:
    Neuroinformatics (rok: 2020, tom: -, strony: online), Wydawca: Humana Press
    Status:
    Published
    DOI:
    10.1007/s12021-020-09487-3 - link to the publication
  3. Network and synaptic mechanisms underlying high frequency oscillations in the rat and cat olfactory bulb under ketamine-xylazine anesthesia
    Authors:
    Średniawa W, Wróbel J, Kublik E, Wójcik DK, Whittington MA, Hunt MJ
    Academic press:
    Scientific Reports (rok: 2021, tom: 11, strony: online/ nr artykułu 6390), Wydawca: Nature
    Status:
    Published
    DOI:
    10.1038/s41598-021-85705-5 - link to the publication
  4. The olfactory bulb is a source of high-frequency oscillations (130–180 Hz) associated with a subanesthetic dose of ketamine in rodents
    Authors:
    Mark Jeremy Hunt, Natalie E Adams, Władysław Średniawa, Daniel K Wójcik, Anna Simon, Stefan Kasicki, Miles Adrian Whittington
    Academic press:
    Neuropsychopharmacology (rok: 2019, tom: volume 44,, strony: 435–442), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/s41386-018-0173-y - link to the publication