Resonance Raman spectroscopy studies of the in vitro and ex vivo haemoglobin adducts with gasotransmitters in biological systems

2016/23/N/ST4/00929

Keywords

Descriptors

  • ST4_3: Metody spektroskopowe i spektrometryczne
  • NZ1_2: Biochemia

Panel

ST4 – Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

Jakub Stanisław Dybaś

Number of co-investigators in the project: 2

Call

PRELUDIUM 12 – announced on 2016-09-15

Amount awarded
99 400 PLN
Project start date
2017-07-26
Project end date
2020-01-25
Project duration
30 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. CompareVOA. Cost: 15 689 PLN
  2. Dysk twardy. Cost: 325 PLN
  3. Dysk twardy przenośny. Cost: 300 PLN
  4. Komputer przenośny. Cost: 3 500 PLN
  5. Lactate Scout.
  6. Objektyw do pomiarów imersyjnych. Cost: 16 000 PLN
  7. Przyrząd wielofunkcyjny Elmetron CX-601.
  8. Zużywalne elementy spektrometru. Cost: 10 000 PLN
  9. chłodziarka GKv Liebherr 242/X31/19. Cost: 3 826 PLN

Information in the final report

Publication in academic press/journals (3)

  1. Probing Heme Active Sites of Hemoglobin in Functional Red Blood Cells Using Resonance Raman Spectroscopy

    Authors:
    J. Dybas, T. Chiura, K. M. Marzec, P. J. Mak
    Academic press:
    The Journal of Physical Chemistry B (year: 2021, volume: 125, pages: 3556-3565), Publisher: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.jpcb.1c01199 – link to the publication
  2. Raman imaging of haem metabolism in situ in macrophages and Kupffer cells

    Authors:
    J. Dybas, M. Grosicki, M. Baranska, K. M. Marzec
    Academic press:
    Analyst (year: 2018, volume: 143, pages: 3489-3498), Publisher: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/C8AN00282G – link to the publication
  3. Spectroscopy-based characterization of Hb–NO adducts in human red blood cells exposed to NO-donor and endothelium-derived NO

    Authors:
    J. Dybas, P. Berkowicz, B. Proniewski, K. Dziedzic-Kocurek, J. Stanek, M. Baranska, S. Chlopicki, K. M. Marzec
    Academic press:
    Analyst (year: 2018, volume: 143, pages: 4335-4346), Publisher: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/C8AN00302E – link to the publication

Book publications / chapters in book publications (1)

  1. 7. Vibrational imaging of proteins: changes in the tissues and cells in the lifestyle disease studies

    Authors:
    K. Majzner, K. Czamara, M. Z. Pacia, J. Dybas, E. Bik, K. Chrabaszcz, E. Wiercigroch, A. Dorosz, A. Wislocka, K. M. Marzec, K. Malek and M. Baranska
    Book:
    Vibrational Spectroscopy in Protein Research (year: 2020, volume: Rozdział 7, pages: 177-218), Publisher: Academic Press
    Status:
    Published

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