Synthesis and microbiological activity of selected phenylboronic compounds

2016/23/B/ST5/02847

Keywords

Descriptors

  • ST5_16: Chemia biologiczna

Panel

ST5 – Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution

Politechnika Warszawska, Wydział Chemiczny

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Agnieszka Adamczyk-Woźniak

Number of co-investigators in the project: 14

Call

OPUS 12 – announced on 2016-09-15

Amount awarded
1 194 980 PLN
Project start date
2017-09-06
Project end date
2021-09-05
Project duration
48 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Kriogeniczny młyn kulowy.. Cost: 90 000 PLN
  2. Waga analityczna.
  3. Zestaw do chromatografii HPLC.. Cost: 270 000 PLN
  4. Zestaw komputerowy. Cost: 6 000 PLN
  5. licencja programu HyperChem 8.0 Professional. Cost: 4 000 PLN

Information in the final report

Publication in academic press/journals (10)

  1. Antifungal activity and tautomeric cyclization equilibria of formylphenylboronic acids

    Authors:
    Krzysztof M. Borys, D. Wieczorek, K. Pecura, J. Lipok, A. Adamczyk-Woźniak
    Academic press:
    Bioorganic Chemistry (year: 2019, volume: 91, pages: 103081), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bioorg.2019.103081 – link to the publication
  2. Synthesis, properties and antimicrobial activity of 5-trifluoromethyl-2-formylphenylboronic acid

    Authors:
    Agnieszka Adamczyk-Woźniak, Jan T. Gozdalik, Dorota Wieczorek, Izabela D. Madura, Ewa Kaczorowska, Ewa Brzezińska, Andrzej Sporzyński, Jacek Lipok
    Academic press:
    Molecules (year: 2020, volume: 25, pages: 799), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules25040799 – link to the publication
  3. Synthesis and structural elucidation of novel antifungal N-(fluorophenyl)piperazinyl benzoxaboroles and their analogues

    Authors:
    K. M. Borys, A. Matuszewska, D. Wieczorek, K. Kopczyńska, J. Lipok, I. D. Madura, A. Adamczyk-Woźniak
    Academic press:
    J. Mol. Struct. (year: 2019, volume: 1181, pages: 587-598), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.molstruc.2019.01.018 – link to the publication
  4. Influence of fluorine substituents on the properties of phenylboronic compounds

    Authors:
    J. T. Gozdalik, A. Adamczyk-Woźniak, A. Sporzyński
    Academic press:
    Pure Appl. Chem. (year: 2018, volume: 90, pages: 677-702), Publisher: De Gruyter
    Status:
    Published
    DOI:
    10.1515/pac-2017-1009 – link to the publication
  5. Vibrational Properties of Benzoxaboroles and Their Interactions with Candida albicans' LeuRS

    Authors:
    Ewa Kaczorowska, Agnieszka Adamczyk-Woźniak, Grażyna Zofia Żukowska, Paulina Kostecka, Andrzej Sporzyński
    Academic press:
    Symmetry (year: 2021, volume: 13, pages: 1845), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/sym13101845 – link to the publication
  6. (Trifluoromethoxy)Phenylboronic Acids: Structures, Properties, and Antibacterial Activity

    Authors:
    Agnieszka Adamczyk-Woźniak, Jan T. Gozdalik, Ewa Kaczorowska, Krzysztof Durka, Dorota Wieczorek, Dorota Zarzeczańska, Andrzej Sporzyński
    Academic press:
    Molecules (year: 2021, volume: 26, pages: a2007), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules26072007 – link to the publication
  7. Mechanochemical synthesis of antifungal bis(benzoxaboroles)

    Authors:
    K. M. Borys, D. Wieczorek, M. Tarkowska, A. Jankowska, J. Lipok, A. Adamczyk-Woźniak
    Academic press:
    RSC Advances (year: 2020, volume: 10, pages: 37187-37193), Publisher: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/d0ra07767d – link to the publication
  8. Synthesis and Influence of 3-Amino Benzoxaboroles Structure on Their Activity against Candida albicans

    Authors:
    1.D. Wieczorek, E. Kaczorowska, M. Wiśniewska, I. D. Madura, M. Leśniak, J. Lipok, A. Adamczyk-Woźniak
    Academic press:
    Molecules (year: 2020, volume: 5999, pages: 46035), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules25245999 – link to the publication
  9. Boronic acids of pharmaceutical importance affect the growth of photosynthetic apparatus of cyjanobacteria in a dose-dependent manner

    Authors:
    E. Niemczyk, J. Pogrzeba, A. Adamczyk-Woźniak, J. Lipok
    Academic press:
    Toxins (year: 2020, volume: 793, pages: 46040), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/toxins12120793 – link to the publication
  10. Synthesis, structure, properties and antimicrobial activity of para trifluoromethyl phenylboronic derivatives

    Authors:
    Agnieszka Adamczyk-Woźniak, Magdalena Tarkowska, Zofia Lazar, Ewa Kaczorowska, Izabela D. Madura, Anna Maria Dąbrowska, Jacek Lipok, Dorota Wieczorek
    Academic press:
    Bioorganic Chemistry (year: 2022, volume: 119, pages: a105560), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bioorg.2021.105560 – link to the publication

Book publications / chapters in book publications (2)

  1. Metody wyodrębniania i oznaczania naturalnych polisacharydów mikroalg

    Authors:
    Weronika Pilis, Jacek Lipok
    Book:
    Na pograniczu chemii i biologii (year: 2020, volume: 39, pages: 199-210), Publisher: Wydawnictwo Naukowe Uniwersytetu im. Adama Mickiewicza w Poznaniu
    Status:
    Published
  2. Diboronic Acids and Their Derivatives: New Perspectives in Sensing and Materials' Chemistry

    Authors:
    A. Adamczyk-Woźniak, A. Sporzyński
    Book:
    Advances in Materials Science Research (year: 2018, volume: 32, pages: 201-233), Publisher: NOVA SCIENCE PUBLISHERS
    Status:
    Published

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Graphic design and implementation: Jakub Piotrowski