Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

The Warburg effect in breast cancer - role of cadmium as the activator of HIF-1 alpha

2016/23/D/NZ7/03645

Keywords:

Warburg effect breast cancer cadmium hypoxia inducible factor 1 alfa

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • NZ7_15: Toxicology
  • NZ7_16: Other related subjects

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Instytut Medycyny Pracy im. prof. dr. med. Jerzego Nofera

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Ewa Jabłońska 

Number of co-investigators in the project: 10

Call: SONATA 12 - announced on 2016-09-15

Amount awarded: 537 995 PLN

Project start date (Y-m-d): 2017-07-14

Project end date (Y-m-d): 2021-07-13

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Komputer z systemem Windows i podstawowym oprogramowaniem (Office, antywirus) oraz drukarką (8 000 PLN)
  2. Przedłużenie programu serwisowego do oprogramowania Statistica Professional 13 PL oraz rozszerzenie licencji ww. oprogramowania o Zestaw Medyczny.
  3. System do rozdziału elektroforetycznego białek (10 000 PLN)
  4. Pozycja do usunięcia.
  5. Zaklejarka termiczna do płytek (16 000 PLN)
  6. Automatyczny homogenizator do tkanek (50 000 PLN)
  7. Program do statystycznej analizy danych (12 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  1. Enviornmental exposure to cadmium in breast cancer - association with the Warburg effect and sensitivity to tamoxifen
    Authors:
    Tarhonska Kateryna, Janasik Beata, Roszak Joanna, Kowalczyk Kornelia, Lesicka Monika, Reszka Edyta, Wieczorek Edyta, Braun Marcin, Kolacinska-Wow Agnieszka, Skokowski Jaroslaw, Kalinowski Leszek, Jablonska Ewa
    Academic press:
    Biomedicine & Pharmacotherapy (rok: 2023, tom: 161, strony: 114435), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.biopha.2023.114435 - link to the publication
  2. Cadmium and breast cancer - current state and research gaps in the underlying mechanisms
    Authors:
    Tarhonska Kateryna, Lesicka Monika, Janasik Beata, Roszak Joanna, Reszka Edyta, Braun Marcin, Kołacińska-Wow Agnieszka, Jabłońska Ewa
    Academic press:
    Toxicology Letters (rok: 2022, tom: 361, strony: 29-42), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.toxlet.2022.03.003 - link to the publication