Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The Warburg effect in breast cancer - role of cadmium as the activator of HIF-1 alpha

2016/23/D/NZ7/03645

Keywords:

Warburg effect breast cancer cadmium hypoxia inducible factor 1 alfa

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • NZ7_15: Toxicology
  • NZ7_16: Other related subjects

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Instytut Medycyny Pracy im. prof. dr. med. Jerzego Nofera

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Ewa Jabłońska 

Number of co-investigators in the project: 10

Call: SONATA 12 - announced on 2016-09-15

Amount awarded: 537 995 PLN

Project start date (Y-m-d): 2017-07-14

Project end date (Y-m-d): 2021-07-13

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Program do statystycznej analizy danych (12 000 PLN)
  2. Automatyczny homogenizator do tkanek (50 000 PLN)
  3. Pozycja do usunięcia.
  4. Zaklejarka termiczna do płytek (16 000 PLN)
  5. Komputer z systemem Windows i podstawowym oprogramowaniem (Office, antywirus) oraz drukarką (8 000 PLN)
  6. Przedłużenie programu serwisowego do oprogramowania Statistica Professional 13 PL oraz rozszerzenie licencji ww. oprogramowania o Zestaw Medyczny.
  7. System do rozdziału elektroforetycznego białek (10 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  1. Cadmium and breast cancer - current state and research gaps in the underlying mechanisms
    Authors:
    Tarhonska Kateryna, Lesicka Monika, Janasik Beata, Roszak Joanna, Reszka Edyta, Braun Marcin, Kołacińska-Wow Agnieszka, Jabłońska Ewa
    Academic press:
    Toxicology Letters (rok: 2022, tom: 361, strony: 29-42), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.toxlet.2022.03.003 - link to the publication
  2. Enviornmental exposure to cadmium in breast cancer - association with the Warburg effect and sensitivity to tamoxifen
    Authors:
    Tarhonska Kateryna, Janasik Beata, Roszak Joanna, Kowalczyk Kornelia, Lesicka Monika, Reszka Edyta, Wieczorek Edyta, Braun Marcin, Kolacinska-Wow Agnieszka, Skokowski Jaroslaw, Kalinowski Leszek, Jablonska Ewa
    Academic press:
    Biomedicine & Pharmacotherapy (rok: 2023, tom: 161, strony: 114435), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.biopha.2023.114435 - link to the publication