Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Evolution of gene regulation as a stochastic process: Savageau's demand theory, cost of regulation and noise

2016/22/E/ST2/00558

Keywords:

evolution fitness landscape stochastic gene expression

Descriptors:

  • ST2_18: Acoustics
  • ST2_14: Non-linear phenomena
  • NZ8_1: Evolutionary biology

Panel:

ST2 - Fundamental constituents of matter: particle, nuclear, plasma, atomic, molecular, gas and optical physics

Host institution :

Instytut Chemii Fizycznej Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Anna Ochab-Marcinek 

Number of co-investigators in the project: 6

Call: SONATA BIS 6 - announced on 2016-06-15

Amount awarded: 628 200 PLN

Project start date (Y-m-d): 2017-05-15

Project end date (Y-m-d): 2023-05-14

Project duration:: 72 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  1. Contributions to the 'noise floor' in gene expression in a population of dividing cells
    Authors:
    Jakub Jędrak, Anna Ochab-Marcinek
    Academic press:
    Scientific Reports (rok: 2020, tom: 10, strony: 13533), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/s41598-020-69217-2 - link to the publication
  2. Exactly solvable model of gene expression in proliferating bacterial cell population with stochastic protein bursts and protein partitioning
    Authors:
    Jakub Jędrak, Maciej Kwiatkowski, Anna Ochab-Marcinek
    Academic press:
    Physical Review E (rok: 2019, tom: 99, strony: 42416), Wydawca: American Physical Society
    Status:
    Published
    DOI:
    10.1103/PhysRevE.99.042416 - link to the publication
  3. Generalization of Powell's results to population out of steady state
    Authors:
    Jakub Jędrak, Marcin Rubin, Anna Ochab-Marcinek
    Academic press:
    Physical Review E (rok: 2023, tom: 108, strony: 24405), Wydawca: American Physical Society
    Status:
    Published
    DOI:
    10.1103/PhysRevE.108.024405 - link to the publication

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