Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Synthesis and physicochemical and biological analysis of crystalline calcium phosphates substituted with various ions.

2016/22/E/ST5/00564

Keywords:

crystalline calcium phospahtes ionic substitutions infrared spectroscopy solid-state NMR spectroscopy

Descriptors:

  • ST5_11:
  • ST5_24:
  • ST5_19:

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Joanna Krystyna Kolmas 

Number of co-investigators in the project: 5

Call: SONATA BIS 6 - announced on 2016-06-15

Amount awarded: 1 241 840 PLN

Project start date (Y-m-d): 2017-05-17

Project end date (Y-m-d): 2022-05-16

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Waga analityczna (4 066 PLN)
  2. Komputer z oprogramowaniem (2 szt.) (10 000 PLN)
  3. Suszarka laboratoryjna (4 797 PLN)
  4. Mieszadło magnetyczne z grzaniem.
  5. kompaktowy spektrometr FT-IR (120 000 PLN)
  6. Lampy do ASA do analizy (P, Se oraz Co-Cr-Cu-Mn-Ni) 3 szt (12 070 PLN)
  7. Wysokotemperaturowy piec komorowy (1500 st.C) (35 000 PLN)
  8. kompaktowy spektrometr Ramana (80 000 PLN)

Information in the final report

  • Publication in academic press/journals (16)
  • Articles in post-conference publications (15)
  • Book publications / chapters in book publications (2)
  1. Dual Doping of Silicon and Manganese in Hydroxyapatites: Physicochemical Properties and Preliminary Biological Studies
    Authors:
    Szurkowska Katarzyna, Drobniewska Agata, Kolmas Joanna.
    Academic press:
    Materials (rok: 2019, tom: 12, strony: 45671), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ma12162566 - link to the publication
  2. Selenium-enriched brushite: A novel biomaterial for potential use in bone tissue engineering
    Authors:
    Aleksandra Laskus, Anna Zgadzaj, Joanna Kolmas
    Academic press:
    International Journal of Molecular Sciences (rok: 2018, tom: 19, strony: 45667), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms19124042 - link to the publication
  3. Selenium-Doped Hydroxyapatite Nanocrystals–Synthesis, Physicochemical Properties and Biological Significance
    Authors:
    Kamil Pajor, Łukasz Pajchel, Barbara Kołodziejska, Joanna Kolmas
    Academic press:
    Crystals (rok: 2018, tom: 8, strony: 45677), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cryst8050188 - link to the publication
  4. Solid-State NMR and Raman Spectroscopic Investigation of Fluoride-Substituted Apatites Obtained in Various Thermal Conditions
    Authors:
    Pajchel L., Borkowski L.
    Academic press:
    Materials (rok: 2021, tom: 14(22), strony: 45670), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ma14226936 - link to the publication
  5. Hydroxyapatites enriched in silicon–Bioceramic materials for biomedical and pharmaceutical applications
    Authors:
    Katarzyna Szurkowska,Joanna Kolmas
    Academic press:
    Progress in Natural Science: Materials International (rok: 2017, tom: 27, strony: 401-409), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.pnsc.2017.08.009 - link to the publication
  6. Zn2+ and SeO32− co-substituted hydroxyapatite: Physicochemical properties and biological usefulness
    Authors:
    Laskus-Zakrzewska Aleksandra, Zgadzaj Anna, Kolmas Joanna.
    Academic press:
    Ceramics International (rok: 2019, tom: 45, strony: 22707 -22715), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ceramint.2019.07.308 - link to the publication
  7. Hydroxyapatite and Fluorapatite in Conservative Dentistry and Oral Implantology-A Review
    Authors:
    Pajor Kamil, Pajchel Łukasz, Kolmas Joanna.
    Academic press:
    Materials (rok: 2019, tom: 12, strony: 45673), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ma12172683 - link to the publication
  8. Ionic Substitutions in Non-Apatitic Calcium Phosphates
    Authors:
    Aleksandra Laskus, Joanna Kolmas
    Academic press:
    International Journal of Molecular Sciences (rok: 2017, tom: 18, strony: 45679), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms18122542 - link to the publication
  9. Novel hybrid material based on Mg2+ and SiO4 4- co-substituted nanohydroxyapatite, alginate and chondroitin sulphate for potential use in biomaterials engineering
    Authors:
    Katarzyna Szurkowska, Anna Zgadzaj, Marzena Kuras, Joanna Kolmas
    Academic press:
    Ceramics International (rok: 2018, tom: 44, strony: 18551-18559), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ceramint.2018.07.077 - link to the publication
  10. Antibacterial and Cytotoxicity Evaluation of New Hydroxyapatite-Based Granules Containing Silver or Gallium Ions with Potential Use as Bone Substitutes
    Authors:
    K. Pajor, A.Michalicha, A. Belcarz, L. Pajchel, A. Zgadzaj, F. Wojas, J. Kolmas
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23(13) 7102, strony: 45677), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms23137102 - link to the publication
  11. Modifications of Hydroxyapatite by Gallium and Silver Ions-Physicochemical Characterization, Cytotoxicity and Antibacterial Evaluation
    Authors:
    Kamil Pajor, Łukasz Pajchel, Anna Zgadzaj, Urszula Piotrowska, Joanna Kolmas
    Academic press:
    International Journal of Molecular Sciences (rok: 2020, tom: 21, strony: 45672), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms21145006 - link to the publication
  12. Effects of synthesis conditions on the formation of Si-substituted alpha tricalcium phosphates
    Authors:
    Katarzyna Szurkowska, Łukasz Szeleszczuk, Joanna Kolmas
    Academic press:
    International Journal of Molecular Sciences (rok: 2020, tom: 21, strony: 45668), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms21239164 - link to the publication
  13. Modifications of Hydroxyapatite by Gallium and Silver Ions-Physicochemical Characterization, Cytotoxicity and Antibacterial Evaluation
    Authors:
    Kamil Pajor, Łukasz Pajchel, Anna Zgadzaj, Urszula Piotrowska, Joanna Kolmas
    Academic press:
    International Journal of Molecular Sciences (rok: 2020, tom: 21, strony: 45672), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms21145006 - link to the publication
  14. Synthesis and physicochemical characterization of Zn-doped brushite
    Authors:
    Laskus-Zakrzewska A., Zgadzaj A., Kolmas J.
    Academic press:
    Ceramics International (rok: 2021, tom: 47, strony: 7798-7804), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ceramint.2020.11.125 - link to the publication
  15. Effects of synthesis conditions on the formation of Si-substituted alpha tricalcium phosphates
    Authors:
    Katarzyna Szurkowska, Łukasz Szeleszczuk, Joanna Kolmas
    Academic press:
    International Journal of Molecular Sciences (rok: 2020, tom: 21, strony: 45668), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms21239164 - link to the publication
  16. Antibacterial and Cytotoxicity Evaluation of New Hydroxyapatite-Based Granules Containing Silver or Gallium Ions with Potential Use as Bone Substitutes
    Authors:
    K. Pajor, A.Michalicha, A. Belcarz, L. Pajchel, A. Zgadzaj, F. Wojas, J. Kolmas
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23(13) 7102, strony: 45677), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms23137102 - link to the publication
  1. Synthesis of hydroxyapatite granules with antibacterial properties
    Authors:
    Pajor K., Zgadzaj A., Pajchel L., Kolmas J.
    Conference:
    Scandinavian Society for Biomaterials (ScSB) 2021 (rok: 2021, ), Wydawca: eCM ecells and materials
    Data:
    konferencja 44361
    Status:
    Published
  2. Composite beads containing hydroxyapatite modified with Mg2+ and SiO44- ions as carriers for antiresorptive drugs
    Authors:
    Katarzyna Szurkowska, Anna Zgadzaj, Joanna Kolmas
    Conference:
    Scandinavian Society for Biomaterials 2019 Conference (rok: 2019, ), Wydawca: e cells and materials
    Data:
    konferencja 12-14.06.2019
    Status:
    Published
  3. SELENIUM – ENRICHED BRUSHITE: A PROMISING MATERIAL FOR POTENTIAL USE IN BONE IMPAIRMENTS TREATMENT
    Authors:
    Aleksandra Laskus, Joanna Kolmas
    Conference:
    27th Conference Biomaterials in Medicine and Veterinary Medicine (rok: 2018, ), Wydawca: Polskie Stowarzyszenie Biomateriałów
    Data:
    konferencja 11-14.10.2018
    Status:
    Published
  4. POROUS HYBRID MATERIALS AS POTENTIAL DRUG DELIVERY SYSTEMS
    Authors:
    Łukasz Pajchel, Agnieszka Szulkowska, Joanna Kolmas
    Conference:
    27th Conference Biomaterials in Medicine and Veterinary Medicine (rok: 2018, ), Wydawca: Polskie Stowarzyszenie Biomateriałów
    Data:
    konferencja 11-14.10.2018
    Status:
    Published
  5. NOVEL ALGINATE AND CHONDROITIN BEADS BASED ON MG AND SI CO-SUBSTITUTED HYDROXYAPATITE
    Authors:
    Katarzyna Szurkowska, Anna Zgadzaj, Joanna Kolmas
    Conference:
    27th conference Biomaterials in Medicine and Veterinary Medicine (rok: 2018, ), Wydawca: Polskie Stowarzyszenie Biomateriałów
    Data:
    konferencja 11-14.10.2018
    Status:
    Published
  6. Solid-State NMR spectroscopy as a tool for the analysis of calcium phosphate biomaterials
    Authors:
    Joanna Kolmas, Łukasz Pajchel, Kamil Pajor
    Conference:
    Scandinavian Society for Biomaterials 2019 Conference (rok: 2019, ), Wydawca: e cells and materials
    Data:
    konferencja 12-14.06.2019
    Status:
    Published
  7. Multicomponent Sr-HA and Ga-BTCP gelatine based scaffolds for biomedical applications
    Authors:
    Katarzyna Szurkowska, Joanna Kolmas
    Conference:
    30th annual conference of the European Society of Biomaterials (rok: 2019, ), Wydawca: ESB
    Data:
    konferencja 9-13.09.2019
    Status:
    Published
  8. Synthesis of silver and gallium doped hydroxyapatites for potential antibacterial properties
    Authors:
    Kamil Pajor, Anna Zgadzaj, Joanna Kolmas
    Conference:
    27th Conference Biomaterials in Medicine and Veterinary Medicine (rok: 2018, ), Wydawca: Polskie Stowarzyszenie Biomateriałów
    Data:
    konferencja 11-14.10.2018
    Status:
    Published
  9. Hydroxyapatite modified with Zn2+ and SeO32- ions: a promising material for bone tissue engineering
    Authors:
    Aleksandra Laskus, Anna Zgadzaj, Joanna Kolmas
    Conference:
    Scandinavian Society for Biomaterials 2019 Conference (rok: 2019, ), Wydawca: e cells and materials
    Data:
    konferencja 12-14.06.2019
    Status:
    Published
  10. Synthesis of calcium phosphates doped with silver and gallium ions as biomaterials with antibacterial properties
    Authors:
    Kamil Pajor, Paulina Kowalska, Urszula Piotrowska, Anna Zgadzaj, Joanna Kolmas
    Conference:
    30th annual conference of the European Society of Biomaterials (rok: 2019, ), Wydawca: ESB
    Data:
    konferencja 9-13.09.2019
    Status:
    Published
  11. Hydroxyapatite modified with Zn2+ and SeO32- ions: a promising material for bone tissue engineering
    Authors:
    Aleksandra Laskus, Anna Zgadzaj, Joanna Kolmas
    Conference:
    Scandinavian Society for Biomaterials 2019 Conference (rok: 2019, ), Wydawca: e cells and materials
    Data:
    konferencja 12-14.06.2019
    Status:
    Published
  12. Zn2+ and SeO3 2- modified hydroxyapatite as a potential, antitumor biomaterial for the therapy of bone cancer
    Authors:
    Aleksandra Laskus, Anna Zgadzaj, Joanna Kolmas
    Conference:
    30th annual conference of the European Society of Biomaterials (rok: 2019, ), Wydawca: ESB
    Data:
    konferencja 9-13.09.2019
    Status:
    Published
  13. Solid-State NMR spectroscopy as a tool for the analysis of calcium phosphate biomaterials
    Authors:
    Joanna Kolmas, Łukasz Pajchel, Kamil Pajor
    Conference:
    Scandinavian Society for Biomaterials 2019 Conference (rok: 2019, ), Wydawca: e cells and materials
    Data:
    konferencja 12-14.06.2019
    Status:
    Published
  14. Various ionic substitutions in hydroxyapatites - physicochemical studies
    Authors:
    Joanna Kolmas, Aleksandra Laskus, Katarzyna Szurkowska, Kamil Pajor, Łukasz Pajchel
    Conference:
    27 th Conference Biomaterials in Medicine and Veterinary Medicine (rok: 2018, ), Wydawca: Polskie Stowarzyszenie Biomateriałów (Engineering of Biomaterials)
    Data:
    konferencja 11-14.10.2018
    Status:
    Published
  15. Composite beads containing hydroxyapatite modified with Mg2+ and SiO44- ions as carriers for antiresorptive drugs
    Authors:
    Katarzyna Szurkowska, Anna Zgadzaj, Joanna Kolmas
    Conference:
    Scandinavian Society for Biomaterials 2019 Conference (rok: 2019, ), Wydawca: e cells and materials
    Data:
    konferencja 12-14.06.2019
    Status:
    Published
  1. Hydroxyapatite-Based Materials for Potential Use in Bone Tissue Infections
    Authors:
    Katarzyna Szurkowska, Aleksandra Laskus, Joanna Kolmas
    Book:
    Hydroxyapatite Advances in Composite Nanomaterials, Biomedical Applications and Its Technological Facets (rok: 2018, tom: 1, strony: 109-135), Wydawca: Intechopen
    Status:
    Published
  2. Hydroxyapatite-Based Materials for Potential Use in Bone Tissue Infections
    Authors:
    Katarzyna Szurkowska, Aleksandra Laskus, Joanna Kolmas
    Book:
    Hydroxyapatite Advances in Composite Nanomaterials, Biomedical Applications and Its Technological Facets (rok: 2018, tom: 1, strony: 109-135), Wydawca: Intechopen
    Status:
    Published

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