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Synthesis and physicochemical and biological analysis of crystalline calcium phosphates substituted with various ions.

2016/22/E/ST5/00564

Keywords

Descriptors

  • ST5_11: Synteza biomateriałów
  • ST5_24: Chemia nieorganiczna
  • ST5_19: Metody badań właściwości materiałów

Panel

ST5 – Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Joanna Krystyna Kolmas

Number of co-investigators in the project: 5

Call

SONATA BIS 6 – announced on 2016-06-15

Amount awarded
1 241 840 PLN
Project start date
2017-05-17
Project end date
2022-05-16
Project duration
60 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Komputer z oprogramowaniem (2 pcs). Cost: 10 000 PLN
  2. Lampy do ASA do analizy (P, Se oraz Co-Cr-Cu-Mn-Ni) 3 szt. Cost: 12 070 PLN
  3. Mieszadło magnetyczne z grzaniem.
  4. Suszarka laboratoryjna. Cost: 4 797 PLN
  5. Waga analityczna. Cost: 4 066 PLN
  6. Wysokotemperaturowy piec komorowy (1500 st.C). Cost: 35 000 PLN
  7. kompaktowy spektrometr FT-IR. Cost: 120 000 PLN
  8. kompaktowy spektrometr Ramana. Cost: 80 000 PLN

Information in the final report

Publication in academic press/journals (13)

  1. Selenium-Doped Hydroxyapatite Nanocrystals–Synthesis, Physicochemical Properties and Biological Significance

    Authors:
    Kamil Pajor, Łukasz Pajchel, Barbara Kołodziejska, Joanna Kolmas
    Academic press:
    Crystals (year: 2018, volume: 8, pages: 46042), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/cryst8050188 – link to the publication

  2. Synthesis and physicochemical characterization of Zn-doped brushite

    Authors:
    Laskus-Zakrzewska A., Zgadzaj A., Kolmas J.
    Academic press:
    Ceramics International (year: 2021, volume: 47, pages: 7798-7804), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ceramint.2020.11.125 – link to the publication

  3. Ionic Substitutions in Non-Apatitic Calcium Phosphates

    Authors:
    Aleksandra Laskus, Joanna Kolmas
    Academic press:
    International Journal of Molecular Sciences (year: 2017, volume: 18, pages: 46044), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms18122542 – link to the publication

  4. Novel hybrid material based on Mg2+ and SiO4 4- co-substituted nanohydroxyapatite, alginate and chondroitin sulphate for potential use in biomaterials engineering

    Authors:
    Katarzyna Szurkowska, Anna Zgadzaj, Marzena Kuras, Joanna Kolmas
    Academic press:
    Ceramics International (year: 2018, volume: 44, pages: 18551-18559), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ceramint.2018.07.077 – link to the publication

  5. Solid-State NMR and Raman Spectroscopic Investigation of Fluoride-Substituted Apatites Obtained in Various Thermal Conditions

    Authors:
    Pajchel L., Borkowski L.
    Academic press:
    Materials (year: 2021, volume: 14(22), pages: 46035), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ma14226936 – link to the publication

  6. Selenium-enriched brushite: A novel biomaterial for potential use in bone tissue engineering

    Authors:
    Aleksandra Laskus, Anna Zgadzaj, Joanna Kolmas
    Academic press:
    International Journal of Molecular Sciences (year: 2018, volume: 19, pages: 46032), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms19124042 – link to the publication

  7. Modifications of Hydroxyapatite by Gallium and Silver Ions-Physicochemical Characterization, Cytotoxicity and Antibacterial Evaluation

    Authors:
    Kamil Pajor, Łukasz Pajchel, Anna Zgadzaj, Urszula Piotrowska, Joanna Kolmas
    Academic press:
    International Journal of Molecular Sciences (year: 2020, volume: 21, pages: 46037), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms21145006 – link to the publication

  8. Hydroxyapatite and Fluorapatite in Conservative Dentistry and Oral Implantology-A Review

    Authors:
    Pajor Kamil, Pajchel Łukasz, Kolmas Joanna.
    Academic press:
    Materials (year: 2019, volume: 12, pages: 46038), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ma12172683 – link to the publication

  9. Zn2+ and SeO32− co-substituted hydroxyapatite: Physicochemical properties and biological usefulness

    Authors:
    Laskus-Zakrzewska Aleksandra, Zgadzaj Anna, Kolmas Joanna.
    Academic press:
    Ceramics International (year: 2019, volume: 45, pages: 22707 -22715), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ceramint.2019.07.308 – link to the publication

  10. Hydroxyapatites enriched in silicon–Bioceramic materials for biomedical and pharmaceutical applications

    Authors:
    Katarzyna Szurkowska,Joanna Kolmas
    Academic press:
    Progress in Natural Science: Materials International (year: 2017, volume: 27, pages: 401-409), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.pnsc.2017.08.009 – link to the publication

  11. Dual Doping of Silicon and Manganese in Hydroxyapatites: Physicochemical Properties and Preliminary Biological Studies

    Authors:
    Szurkowska Katarzyna, Drobniewska Agata, Kolmas Joanna.
    Academic press:
    Materials (year: 2019, volume: 12, pages: 46036), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ma12162566 – link to the publication

  12. Effects of synthesis conditions on the formation of Si-substituted alpha tricalcium phosphates

    Authors:
    Katarzyna Szurkowska, Łukasz Szeleszczuk, Joanna Kolmas
    Academic press:
    International Journal of Molecular Sciences (year: 2020, volume: 21, pages: 46033), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms21239164 – link to the publication

  13. Antibacterial and Cytotoxicity Evaluation of New Hydroxyapatite-Based Granules Containing Silver or Gallium Ions with Potential Use as Bone Substitutes

    Authors:
    K. Pajor, A.Michalicha, A. Belcarz, L. Pajchel, A. Zgadzaj, F. Wojas, J. Kolmas
    Academic press:
    International Journal of Molecular Sciences (year: 2022, volume: 23(13) 7102, pages: 46042), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms23137102 – link to the publication

Articles in post-conference publications (12)

  1. Zn2+ and SeO3 2- modified hydroxyapatite as a potential, antitumor biomaterial for the therapy of bone cancer

    Authors:
    Aleksandra Laskus, Anna Zgadzaj, Joanna Kolmas
    Conference:
    30th annual conference of the European Society of Biomaterials (year: 2019, pages: 906-907), Publisher: ESB
    Date:
    conference 9-13.09.2019
    Status:
    Published

  2. Synthesis of calcium phosphates doped with silver and gallium ions as biomaterials with antibacterial properties

    Authors:
    Kamil Pajor, Paulina Kowalska, Urszula Piotrowska, Anna Zgadzaj, Joanna Kolmas
    Conference:
    30th annual conference of the European Society of Biomaterials (year: 2019, pages: 1147-1148), Publisher: ESB
    Date:
    conference 9-13.09.2019
    Status:
    Published

  3. Multicomponent Sr-HA and Ga-BTCP gelatine based scaffolds for biomedical applications

    Authors:
    Katarzyna Szurkowska, Joanna Kolmas
    Conference:
    30th annual conference of the European Society of Biomaterials (year: 2019, pages: 904-905), Publisher: ESB
    Date:
    conference 9-13.09.2019
    Status:
    Published

  4. Composite beads containing hydroxyapatite modified with Mg2+ and SiO44- ions as carriers for antiresorptive drugs

    Authors:
    Katarzyna Szurkowska, Anna Zgadzaj, Joanna Kolmas
    Conference:
    Scandinavian Society for Biomaterials 2019 Conference (year: 2019, pages: 62), Publisher: e cells and materials
    Date:
    conference 12-14.06.2019
    Status:
    Published

  5. Solid-State NMR spectroscopy as a tool for the analysis of calcium phosphate biomaterials

    Authors:
    Joanna Kolmas, Łukasz Pajchel, Kamil Pajor
    Conference:
    Scandinavian Society for Biomaterials 2019 Conference (year: 2019, pages: 51), Publisher: e cells and materials
    Date:
    conference 12-14.06.2019
    Status:
    Published

  6. Hydroxyapatite modified with Zn2+ and SeO32- ions: a promising material for bone tissue engineering

    Authors:
    Aleksandra Laskus, Anna Zgadzaj, Joanna Kolmas
    Conference:
    Scandinavian Society for Biomaterials 2019 Conference (year: 2019, pages: 52), Publisher: e cells and materials
    Date:
    conference 12-14.06.2019
    Status:
    Published

  7. POROUS HYBRID MATERIALS AS POTENTIAL DRUG DELIVERY SYSTEMS

    Authors:
    Łukasz Pajchel, Agnieszka Szulkowska, Joanna Kolmas
    Conference:
    27th Conference Biomaterials in Medicine and Veterinary Medicine (year: 2018, pages: 43), Publisher: Polskie Stowarzyszenie Biomateriałów
    Date:
    conference 11-14.10.2018
    Status:
    Published

  8. Various ionic substitutions in hydroxyapatites - physicochemical studies

    Authors:
    Joanna Kolmas, Aleksandra Laskus, Katarzyna Szurkowska, Kamil Pajor, Łukasz Pajchel
    Conference:
    27 th Conference Biomaterials in Medicine and Veterinary Medicine (year: 2018, pages: 45), Publisher: Polskie Stowarzyszenie Biomateriałów (Engineering of Biomaterials)
    Date:
    conference 11-14.10.2018
    Status:
    Published

  9. SELENIUM – ENRICHED BRUSHITE: A PROMISING MATERIAL FOR POTENTIAL USE IN BONE IMPAIRMENTS TREATMENT

    Authors:
    Aleksandra Laskus, Joanna Kolmas
    Conference:
    27th Conference Biomaterials in Medicine and Veterinary Medicine (year: 2018, pages: 16), Publisher: Polskie Stowarzyszenie Biomateriałów
    Date:
    conference 11-14.10.2018
    Status:
    Published

  10. Synthesis of hydroxyapatite granules with antibacterial properties

    Authors:
    Pajor K., Zgadzaj A., Pajchel L., Kolmas J.
    Conference:
    Scandinavian Society for Biomaterials (ScSB) 2021 (year: 2021, pages: p12), Publisher: eCM ecells and materials
    Date:
    conference 44361
    Status:
    Published

  11. NOVEL ALGINATE AND CHONDROITIN BEADS BASED ON MG AND SI CO-SUBSTITUTED HYDROXYAPATITE

    Authors:
    Katarzyna Szurkowska, Anna Zgadzaj, Joanna Kolmas
    Conference:
    27th conference Biomaterials in Medicine and Veterinary Medicine (year: 2018, pages: 29), Publisher: Polskie Stowarzyszenie Biomateriałów
    Date:
    conference 11-14.10.2018
    Status:
    Published

  12. Synthesis of silver and gallium doped hydroxyapatites for potential antibacterial properties

    Authors:
    Kamil Pajor, Anna Zgadzaj, Joanna Kolmas
    Conference:
    27th Conference Biomaterials in Medicine and Veterinary Medicine (year: 2018, pages: 46), Publisher: Polskie Stowarzyszenie Biomateriałów
    Date:
    conference 11-14.10.2018
    Status:
    Published

Book publications / chapters in book publications (1)

  1. Hydroxyapatite-Based Materials for Potential Use in Bone Tissue Infections

    Authors:
    Katarzyna Szurkowska, Aleksandra Laskus, Joanna Kolmas
    Book:
    Hydroxyapatite Advances in Composite Nanomaterials, Biomedical Applications and Its Technological Facets (year: 2018, volume: 1, pages: 109-135), Publisher: Intechopen
    Status:
    Published

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Graphic design and implementation: Jakub Piotrowski