How HPV16 infection influences EGFR/PI3K/AKT/mTOR pathway in squamous cell cancer of head and neck?

2016/21/N/NZ5/00227

Keywords

Descriptors

  • NZ5_7: Leczenie chorób człowieka
  • NZ5_1: Etiologia chorób człowieka

Panel

NZ5 – Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Krakowie

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

Anna Janecka-Widła

Number of co-investigators in the project: 3

Call

PRELUDIUM 11 – announced on 2016-03-15

Amount awarded
150 000 PLN
Project start date
2017-03-07
Project end date
2021-03-06
Project duration
48 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (3)

  1. Active HPV infection and its influence on survival in head and neck squamous-cell cancer

    Authors:
    Janecka-Widła A, Mucha-Małecka A, Majchrzyk K, Halaszka K, Przewoźnik M, Słonina D, Biesaga B
    Academic press:
    Journal of Cancer Research and Clinical Oncology (year: 2020, volume: 146(7), pages: 1677–1692), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/s00432-020-03218-6 – link to the publication
  2. EGFR/PI3K/Akt/mTOR pathway in head and neck squamous cell carcinoma patients with different HPV status

    Authors:
    Janecka-Widła A, Majchrzyk K, Mucha-Małecka A, Biesaga B
    Academic press:
    Polish Journal of Pathology (year: 2021, volume: 73(4), pages: 46041), Publisher: Termedia
    Status:
    Published
    DOI:
    10.5114/pjp.2021.113073 – link to the publication
  3. Prognostic potential of Akt, pAkt(Ser473) and pAkt(Thr308) immunoreactivity in relation to HPV prevalence in head and neck squamous cell carcinoma patients

    Authors:
    Janecka-Widła A, Majchrzyk K, Mucha-Małecka A, Słonina D, Biesaga B
    Academic press:
    Pathology - Research and Practice (year: 2022, volume: 229, pages: 153684), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.prp.2021.153684 – link to the publication

Articles in post-conference publications (3)

  1. The prevalence of HPV in head and neck squamous cell cancer tissues of patients from South-Central Poland

    Authors:
    Janecka-Widła A, Mucha-Małecka A, Przewoźnik M, Halaszka K, Szostek S, Kowalczyk A, Słonina D, Biesaga B
    Conference:
    EUROGIN - International Multidisciplinary HPV Congress (year: 2017, pages: 261-262), Publisher: brak danych
    Date:
    conference 8-11 październik
    Status:
    Published
  2. Wpływ HPV16 na ekspresję EGFR, AKT i PTEN w płaskonabłonkowych nowotworach terenu głowy i szyi u chorych z południowej i centralnej Polski

    Authors:
    Janecka-Widła A, Mucha-Małecka A, Halaszka K, Przewoźnik M, Szostek S, Kowalczyk A, Słonina D, Biesaga B
    Conference:
    XX Kongres Polskiego Towarzystwa Onkologii Klinicznej (year: 2017, pages: B18), Publisher: Via Medica sp. z o.o.
    Date:
    conference 14 - 16 września
    Status:
    Published
  3. Akt and pAkt expression and their prognostic significance in HPV16 positive and HPV negative head and neck squamous cell cancer patients

    Authors:
    Janecka-Widła A, Majchrzyk K, Mucha-Małecka A, Biesaga B
    Conference:
    34th International Papillomavirus Conference (IPVC 2021) (year: 2021, pages: 124), Publisher: International Papillomavirus Society
    Date:
    conference 15-19 listopad
    Status:
    Published

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