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The search for a marker differentiating the different stages od NAFLD/NASH through the analysis of the correlations of fatty acids and their derivatives in the blood and liver of rats with a model of fatty liver

2016/21/N/NZ5/02584

Keywords:

nonalcoholic fatty liver disease eicosanoids fatty acids makrer,

Descriptors:

  • NZ5_3: Pathogenesis of human diseases
  • NZ5_5: Diagnostics in human diseases
  • NZ4_4: Pathophysiology

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Pomorski Uniwersytet Medyczny w Szczecinie, Wydział Nauk o Zdrowiu

woj. zachodniopomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Dominika Maciejewska-Markiewicz 

Number of co-investigators in the project: 3

Call: PRELUDIUM 11 - announced on 2016-03-15

Amount awarded: 147 720 PLN

Project start date (Y-m-d): 2017-03-02

Project end date (Y-m-d): 2020-12-01

Project duration:: 45 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. Diet-Induced Rat Model of Gradual Development of Non-Alcoholic Fatty Liver Disease (NAFLD) with Lipopolysaccharides (LPS) Secretion
    Authors:
    Dominika Maciejewska, Agnieszka Łukomska, Karolina Dec, Karolina Skonieczna-Żydecka, Izabela Gutowska, Marta Skórka-Majewicz, Daniel Styburski, Kamila Misiakiewicz-Has, Anna Pilutin, Joanna Palma, Katarzyna Sieletycka, Wojciech Marlicz, Ewa Stachowska
    Academic press:
    Diagnostics (rok: 2019, tom: 9, strony: 205), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/diagnostics9040205 - link to the publication
  2. Is the Fatty Acids Profile in Blood a Good Predictor of Liver Changes? Correlation of Fatty Acids Profile with Fatty Acids Content in the Liver
    Authors:
    Dominika Maciejewska, Joanna Palma, Karolina Dec, Karolina Skonieczna-Żydecka, Izabela Gutowska, Małgorzata Szczuko, Karolina Jakubczyk, Ewa Stachowska
    Academic press:
    Diagnostics (rok: 2019, tom: 9, strony: 197), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/diagnostics9040197 - link to the publication
  3. The short chain fatty acids and lipopolysaccharides status in Sprague-Dawley rats fed with high-fat and high-cholesterol diet
    Authors:
    Maciejewska Dominika, Skonieczna-Zydecka Karolina, Lukomska Agnieszka, Gutowska Izabela, Dec Karolina, Kupnicka Patrycja, Palma Joanna, Pilutin Anna, Marlicz Wojcich, Stachowska Ewa
    Academic press:
    JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 2018, 69, 2, 205-210 (rok: 2018, tom: 69, strony: 205-210), Wydawca: Polish Physiological Society, formerly as Acta Physiologica Polonica
    Status:
    Published
    DOI:
    10.26402/jpp.2018.2.05 - link to the publication
  4. Eicosanoids in nonalcoholic fatty liver disease (NAFLD) progression. Do serum eicosanoids profile correspond with liver eicosanoids content, during NAFLD development and progression?
    Authors:
    Dominika Maciejewska, Arleta Drozd, Karolina Skonieczna-Żydecka, Marta Skórka-Majewicz, Karolina Dec, Karolina Jakubczyk, Anna Pilutin, Ewa Stachowska
    Academic press:
    Molecules (rok: 2020, tom: 25, strony: 2026), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules25092026 - link to the publication

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