Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Regulation of transcription of genes from the Grainyhead-like family in human cells, in the context of cancer.

2016/21/B/NZ1/00279

Keywords:

transcription factors regulation of gene expression Grainyhead-like cancer

Descriptors:

  • NZ1_1: Molecular biology
  • NZ1_2: Biochemistry
  • NZ2_1: Molecular genetics

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Warszawski, Wydział Biologii

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Tomasz Wilanowski 

Number of co-investigators in the project: 5

Call: OPUS 11 - announced on 2016-03-15

Amount awarded: 1 088 000 PLN

Project start date (Y-m-d): 2017-01-23

Project end date (Y-m-d): 2021-06-22

Project duration:: 53 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. autoklaw Classic 2100 04.
  2. komputer z monitorem.
  3. urządzenie wielofunkcyjne HPLaserJet Pro MF281fdn.
  4. zasilacz Powerpac Basic Power.
  5. Komputery osobiste z monitorami i oprogramowaniem (2 szt.) (20 000 PLN)
  6. kuchenki mikrofalowe.
  7. waga precyzyjna, łaźnia wodna.
  8. licencja na oprogramowanie (900 PLN)
  9. licencje na oprogramowanie.
  10. oprogramowanie EndNote.
  11. Stacja robocza z monitorem do analiz bioinformatycznych (10 000 PLN)
  12. licencja na oprogramowanie BioSolveIt.
  13. palnik z podstawką.
  14. Wirówka laboratoryjna z chłodzeniem (20 000 PLN)
  15. wirówka VWR Ministar.
  16. wirówka laboratoryjna MPW-352R.
  17. zestaw do elektroforezy i transferu bialek.

Information in the final report

  • Publication in academic press/journals (7)
  • Articles in post-conference publications (5)
  1. Transcription factors Krüppel-like factor 4 and paired box 5 regulate the expression of the Grainyhead-like genes
    Authors:
    Kotarba G, Taracha-Wisniewska A, Miller M, Dabrowski M, Wilanowski T
    Academic press:
    PLoS One (rok: 2021, tom: 16, strony: e0257977), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pone.0257977 - link to the publication
  2. TFCP2/TFCP2L1/UBP1 transcription factors in cancer.
    Authors:
    Kotarba G, Krzywinska E, Grabowska AI, Taracha A, Wilanowski T
    Academic press:
    Cancer Letters (rok: 2018, tom: 420, strony: 72-79), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.canlet.2018.01.078 - link to the publication
  3. Metody analizy fosforylacji białek.
    Authors:
    Taracha A, Kotarba G, Wilanowski T
    Academic press:
    Postępy Biochemii (rok: 2017, tom: 63, strony: 137-142), Wydawca: Polskie Towarzystwo Biochemiczne
    Status:
    Published
    DOI:
    brak - link to the publication
  4. Neglected functions of TFCP2/TFCP2L1/UBP1 transcription factors may offer valuable insights into their mechanisms of action.
    Authors:
    Taracha A, Kotarba G, Wilanowski T
    Academic press:
    International Journal of Molecular Sciences (rok: 2018, tom: 19, strony: 2852), Wydawca: MDPI (Multidisciplinary Digital Publishing Institute)
    Status:
    Published
    DOI:
    10.3390/ijms19102852 - link to the publication
  5. Recent Discoveries on the Involvement of Krüppel-Like Factor 4 in the Most Common Cancer Types
    Authors:
    Taracha-Wiśniewska A, Kotarba G, Dworkin S, Wilanowski T
    Academic press:
    International Journal of Molecular Sciences (rok: 2020, tom: 21, strony: 8843), Wydawca: MDPI (Multidisciplinary Digital Publishing Institute)
    Status:
    Published
    DOI:
    10.3390/ijms21228843 - link to the publication
  6. Regulation of S100A10 gene expression
    Authors:
    Glowacka A, Bieganowski P, Jurewicz E, Lesniak W, Wilanowski T, Filipek A
    Academic press:
    Biomolecules (rok: 2021, tom: 11, strony: 974), Wydawca: MDPI (Multidisciplinary Digital Publishing Institute)
    Status:
    Published
    DOI:
    10.3390/biom11070974 - link to the publication
  7. Grainyhead-like transcription factors in cancer - Focus on recent developments
    Authors:
    Kotarba G, Taracha-Wisniewska A, Wilanowski T
    Academic press:
    Experimental Biology and Medicine (rok: 2020, tom: 245, strony: 402-410), Wydawca: Society for Experimental Biology and Medicine
    Status:
    Published
    DOI:
    10.1177/1535370220903009 - link to the publication
  1. Grainyhead-like transcription factors as targets of anti-cancer therapy.
    Authors:
    Wilanowski T
    Conference:
    BIO 2018 Congress (rok: 2018, ), Wydawca: Acta Biochimica Polonica 65 Suppl. 2: 85; Polskie Towarzystwo Biochemiczne; Polska Akademia Nauk
    Data:
    konferencja 18-21.09.2018
    Status:
    Published
  2. Regulation of expression of genes from the Grainyhead-like family (GRHL) - new molecular insights into cancer development
    Authors:
    Taracha A, Kotarba G, Miller M, Dabrowski M, Wilanowski T
    Conference:
    Heterogeneity and Evolution in Cancer (rok: 2019, ), Wydawca: Centro Nacional de Investigaciones Oncológicas (CNIO)
    Data:
    konferencja 23-25.09
    Status:
    Published
  3. Regulation of expression of genes from the Grainyhead-like family (GRHL) by transcription factors
    Authors:
    Taracha-Wisniewska A, Kotarba G, Miller M, Dabrowski M, Wilanowski T
    Conference:
    FEBS Congress 2021 (rok: 2021, ), Wydawca: Federation of European Biochemical Societies (FEBS)
    Data:
    konferencja 3-8 lipca
    Status:
    Published
  4. Regulation of expression of genes from the Grainyhead-like family (GRHL) - new molecular insights into cancer development
    Authors:
    Taracha A, Kotarba G, Miller M, Dabrowski M, Wilanowski T
    Conference:
    FEBS Congress 2019 (rok: 2019, ), Wydawca: Federation of European Biochemical Societies (FEBS)
    Data:
    konferencja 6-11 lipca
    Status:
    Published
  5. Transcription factors regulating the expression of genes from the Grainyhead-like (GRHL) family in the context of human cancer
    Authors:
    Taracha A, Kotarba G, Wilanowski T
    Conference:
    BIO 2018 Congress (rok: 2018, ), Wydawca: Acta Biochimica Polonica 65 Suppl. 2: 91; Polskie Towarzystwo Biochemiczne; Polska Akademia Nauk
    Data:
    konferencja 18-21.09.2018
    Status:
    Published

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