Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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An investigation into novel mechanisms of regulation of gene expression in the context of interactions between host and Staphylococcus aureus cells during pathogenesis

2016/21/D/NZ1/00273

Keywords:

Staphylococcus aureus gronkowiec złocisty toxin-antitoxin systems mRNA interferases gene expression regulation internalisation host-pathogen interaction

Descriptors:

  • NZ1_10: Microbiology
  • NZ1_1: Molecular biology
  • NZ6_4: Bacteriology

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Michał Bukowski 

Number of co-investigators in the project: 3

Call: SONATA 11 - announced on 2016-03-15

Amount awarded: 397 000 PLN

Project start date (Y-m-d): 2017-03-08

Project end date (Y-m-d): 2022-03-07

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Miniwirówka (2 000 PLN)
  2. Termocykler (25 000 PLN)
  3. Zestaw do elektroforezy DNA/RNA (4 000 PLN)
  4. Inkubator CO2 (30 000 PLN)
  5. Zestaw komputerowy wraz z monitorem (4 500 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  1. Disruption of saoB and saoC genes in Staphylococcus aureus alters transcription of genes involved in amino acid metabolism and virulence
    Authors:
    Michal Bukowski, Maja Kosecka-Strojek, Benedykt Wladyka
    Academic press:
    Research in Microbiology , Wydawca: Elsevier
    Status:
    Submitted
  2. Staphylococcal saoABC operon codes for a DNA-binding protein SaoC implicated in the response to nutrient deficit
    Authors:
    Michal Bukowski, Maja Kosecka-Strojek, Anna Madry, Rafal Zagorski-Przybylo, Tomasz Zadlo, Katarzyna Gawron, Benedykt Wladyka
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23(12), strony: 6443), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms23126443 - link to the publication