Projects funded by the NCN
A novel, non-enzymatic mechanism of action of gingipains as potent major virulence factors of Porphyromonas gingivalis.
2016/21/N/NZ6/01133
Keywords:
gingipains periodontitis inflammation cell signaling pathways moonlight proteins
Descriptors:
- NZ6_1: Adaptive and innate immunity
- NZ3_7: Signal transduction
- NZ6_4: Bacteriology
Panel:
NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology
Host institution :
UNIWERSYTET JAGIELLOŃSKI, Wydział Biochemii, Biofizyki i Biotechnologii
woj. małopolskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 11 - announced on 2016-03-15
Amount awarded: 99 960 PLN
Project start date (Y-m-d): 2017-02-20
Project end date (Y-m-d): 2019-02-19
Project duration:: 24 months (the same as in the proposal)
Project status: Project settled
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (1)
- Inactive Gingipains from P. gingivalis Selectively Skews T Cells toward a Th17 Phenotype in an IL-6 Dependent Manner.Authors:Glowczyk I, Wong A, Potempa B, Babyak O, Lech M, Lamont RJ, Potempa J, Koziel J.Academic press:Frontiers in Cellular and Infectious Microbiology (rok: 2017, tom: 7, strony: Article 140), Wydawca: FrontiersStatus:PublishedDOI:10.3389/fcimb.2017.00140 - link to the publication