Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Studies of the interaction of copper-based complexes with DNA by means of X-ray spectroscopy techniques

2016/21/D/ST4/00378

Keywords:

drug-DNA interaction X-ray absorption spectroscopy X-ray emission spectroscopy

Descriptors:

  • ST4_3: Molecular architecture and structure
  • ST4_13: Solid-state chemistry, surface physicochemistry

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Instytut Fizyki Jądrowej im. Henryka Niewodniczańskiego Polskiej Akademii Nauk

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Joanna Czapla-Masztafiak 

Number of co-investigators in the project: 3

Call: SONATA 11 - announced on 2016-03-15

Amount awarded: 641 200 PLN

Project start date (Y-m-d): 2017-02-20

Project end date (Y-m-d): 2022-02-19

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Lampa rentgenowska z mikrogniskowaniem (160 000 PLN)
  2. Pompa mikrostrumieniowa (8 000 PLN)
  3. Segmentowe krzemowe kryształy dyfrakcyjne (2 szt.) (10 000 PLN)
  4. Detektor CCD (2 szt.) (160 000 PLN)
  5. Spektrofotometr UV-Vis wyposażony w światłowody (45 510 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  1. A laboratory-based double X-ray spectrometer for simultaneous X-ray emission and X-ray absorption studies
    Authors:
    Wojciech Błachucki, Joanna Czapla-Masztafiak, Jacinto Sá, Jakub Szlachetko
    Academic press:
    Journal of Analytical Atomic Spectrometry (rok: 2019, tom: 34, strony: 1409-1415), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/c9ja00159j - link to the publication
  2. The use of the X-ray absorption spectroscopy laboratory setup in the examination of copper(II) compounds for biomedical applications
    Authors:
    Wiktoria Stańczyk, Joanna Czapla-Masztafiak
    Academic press:
    Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms (rok: 2021, tom: 497, strony: 65-69), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.nimb.2021.03.027 - link to the publication
  3. Mechanism of hydrolysis of a platinum(IV) complex discovered by atomic telemetry
    Authors:
    Joanna Czapla-Masztafiak, Adam Kubas,Yves Kayser, Daniel L.A. Fernandes, Wojciech M. Kwiatek, Ewelina Lipiec, Glen B. Deacon, Khansa Al-Jorani, Bayden R.Wood, Jakub Szlachetko, Jacinto Sá
    Academic press:
    Journal of Inorganic Biochemistry (rok: 2018, tom: 187, strony: 56-61), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jinorgbio.2018.07.012 - link to the publication
  4. A von Hamos spectrometer for in situ sulfur speciation by non-resonant sulfur Kα emission spectroscopy
    Authors:
    Dzulija Kuzmenko, Urs Vogelsang, Stephan Hitz, David Müller, Adam H. Clark, Dominik Kinschel, Joanna Czapla-Masztafiak, Christopher Milne, Jakub Szlachetko, Maarten Nachtegaal
    Academic press:
    Journal of Analytical Atomic Spectrometry (rok: 2019, tom: 34, strony: 2105-2111), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/c9ja00195f - link to the publication