Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Studies of the interaction of copper-based complexes with DNA by means of X-ray spectroscopy techniques

2016/21/D/ST4/00378

Keywords:

drug-DNA interaction X-ray absorption spectroscopy X-ray emission spectroscopy

Descriptors:

  • ST4_3: Molecular architecture and structure
  • ST4_13: Solid-state chemistry, surface physicochemistry

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Instytut Fizyki Jądrowej im. Henryka Niewodniczańskiego Polskiej Akademii Nauk

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Joanna Czapla-Masztafiak 

Number of co-investigators in the project: 3

Call: SONATA 11 - announced on 2016-03-15

Amount awarded: 641 200 PLN

Project start date (Y-m-d): 2017-02-20

Project end date (Y-m-d): 2022-02-19

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Segmentowe krzemowe kryształy dyfrakcyjne (2 szt.) (10 000 PLN)
  2. Spektrofotometr UV-Vis wyposażony w światłowody (45 510 PLN)
  3. Pompa mikrostrumieniowa (8 000 PLN)
  4. Detektor CCD (2 szt.) (160 000 PLN)
  5. Lampa rentgenowska z mikrogniskowaniem (160 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  1. The use of the X-ray absorption spectroscopy laboratory setup in the examination of copper(II) compounds for biomedical applications
    Authors:
    Wiktoria Stańczyk, Joanna Czapla-Masztafiak
    Academic press:
    Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms (rok: 2021, tom: 497, strony: 65-69), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.nimb.2021.03.027 - link to the publication
  2. Mechanism of hydrolysis of a platinum(IV) complex discovered by atomic telemetry
    Authors:
    Joanna Czapla-Masztafiak, Adam Kubas,Yves Kayser, Daniel L.A. Fernandes, Wojciech M. Kwiatek, Ewelina Lipiec, Glen B. Deacon, Khansa Al-Jorani, Bayden R.Wood, Jakub Szlachetko, Jacinto Sá
    Academic press:
    Journal of Inorganic Biochemistry (rok: 2018, tom: 187, strony: 56-61), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jinorgbio.2018.07.012 - link to the publication
  3. A laboratory-based double X-ray spectrometer for simultaneous X-ray emission and X-ray absorption studies
    Authors:
    Wojciech Błachucki, Joanna Czapla-Masztafiak, Jacinto Sá, Jakub Szlachetko
    Academic press:
    Journal of Analytical Atomic Spectrometry (rok: 2019, tom: 34, strony: 1409-1415), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/c9ja00159j - link to the publication
  4. A von Hamos spectrometer for in situ sulfur speciation by non-resonant sulfur Kα emission spectroscopy
    Authors:
    Dzulija Kuzmenko, Urs Vogelsang, Stephan Hitz, David Müller, Adam H. Clark, Dominik Kinschel, Joanna Czapla-Masztafiak, Christopher Milne, Jakub Szlachetko, Maarten Nachtegaal
    Academic press:
    Journal of Analytical Atomic Spectrometry (rok: 2019, tom: 34, strony: 2105-2111), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/c9ja00195f - link to the publication

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