Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Dehydropeptides as substrates for synthesis of building blocks for construction artzymes

2016/21/B/ST5/00115

Keywords:

dehydropeptides oxazolines peptide mimetics conformations

Descriptors:

  • ST5_16:
  • ST5_23:
  • ST5_22:

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Politechnika Wrocławska

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Paweł Kafarski 

Number of co-investigators in the project: 6

Call: OPUS 11 - announced on 2016-03-15

Amount awarded: 793 330 PLN

Project start date (Y-m-d): 2017-02-09

Project end date (Y-m-d): 2021-02-08

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Pompa membranowa (7 000 PLN)
  2. chromatograf typu "Flash" (170 000 PLN)

Information in the final report

  • Publication in academic press/journals (5)
  • Book publications / chapters in book publications (1)
  1. Dipeptides of S-Substituted Dehydrocysteine as Artzyme Building Blocks: Synthesis, Complexing Abilities and Antiproliferative Properties
    Authors:
    Lenartowicz,P.; Psurski, M.; Kotynia, A.; Pieniężna, A.; Cuprych, M.; Poniatowska, K.; Brasuń, J. Kafarski, P.
    Academic press:
    International Journal of Molecular Science (rok: 2021, tom: 22 (2168), strony: 45304), Wydawca: mdpi
    Status:
    Published
    DOI:
    10.3390/ijms22042168 - link to the publication
  2. A novel approach for obtaining alpha,beta-diaminophosphonates bearing structurally diverseside chains and their interactions with transition metal ions studied by ITC
    Authors:
    Lenartowicz, P.; Witkowska, D.; Żyszka-Haberecht, B.; Dziuk, B.; Ejsmont, K.; Świątek-Kozłowska, J.; Kafarski, P.
    Academic press:
    RSC Advances (rok: 2020, tom: 10, strony: 24045 - 24056), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/d0ra03764h - link to the publication
  3. Phosphonopeptides containing free phosphonic groups: recent advances
    Authors:
    Kafarski, P.
    Academic press:
    RSC Advances (rok: 2020, tom: 10, strony: 25898 - 25910), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/d0ra04655h - link to the publication
  4. Access to α-Aminophosphonic Acid Derivatives and Phosphonopeptides by [Rh(P–OP)]-Catalyzed Stereoselective Hydrogenation
    Authors:
    Fernández-Pérez, H.; Lenartowicz, P.; Carreras, L.; Grabulosa, A.; Kafarski, P. Vidal-Ferran, A.
    Academic press:
    Journal of Organic Chemistry (rok: 2020, tom: 85, strony: 14779 - 14784), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.joc.0c00914 - link to the publication
  5. Michael additions to double bonds of esters of N-protected (s)-phenylalanyldehydroalanine (X-(s)-Phe-ΔAla-OMe) and its phosphonic acid counterpart (X-(s)-Phe-ΔAla-PO(OEt)2)
    Authors:
    Lenartowicz, P., Dziuk, B.; Zarychta, B.; Makowski, M.; Kafarski P.
    Academic press:
    Phosphorus, Sulfur, Silicon Related Elements (rok: 2017, tom: 192(6), strony: 706-712), Wydawca: Taylor& Francis
    Status:
    Published
    DOI:
    10.1080/10426507.2017.1308933 - link to the publication
  1. Phosphonates: Their Natural Occurrence and Physiological Role
    Authors:
    Paweł Kafarski
    Book:
    Biological Role of Phosphorus (rok: 2020, tom: 1, strony: 557-577), Wydawca: Intech Open
    Status:
    Published

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