Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Studies on calcium deposits and growth factors in longitudinal septa of cartilage growth plate for better understanding of physiological ossification and development of clinically useful biomaterials stimulating bone formation

2016/21/B/NZ1/00289

Keywords:

cartilage growth plate,

Descriptors:

  • NZ1_8: Tissue engineering

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Warszawski Uniwersytet Medyczny, Wydział Lekarski

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Stanisław Moskalewski 

Number of co-investigators in the project: 6

Call: OPUS 11 - announced on 2016-03-15

Amount awarded: 819 760 PLN

Project start date (Y-m-d): 2017-02-27

Project end date (Y-m-d): 2023-02-26

Project duration:: 72 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Liofilizator Labconco Free Zone 6L (100 860 PLN)
  2. autoklaw.
  3. pompa próżniowa.

Information in the final report

  • Publication in academic press/journals (6)
  1. Formation of calcium phosphate coatings within polycaprolactone scaffolds by simple, alkaline phosphatase based method
    Authors:
    Jakub Jaroszewicz, Joanna Idaszek, Emilia Choińska, Karol szlazak, Anna Hyc, Anna Osiecka-Iwan, Wojciech Święszkowski, Stanisław Moskalewski
    Academic press:
    Materials Science & Engineering C (rok: 2019, tom: 96, strony: 319-328), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.msec.2018.11.027 - link to the publication
  2. Growth factor profile in calcified cartilage from the metaphysis of a calf costochondral junction, the site of initial bone formation.
    Authors:
    Anna Iwan, Stanisław Moskalewski, Anna Hyc
    Academic press:
    Biomedical Reports (rok: 2021, tom: 14, strony: 1-10- 0n line), Wydawca: Spandidos publications
    Status:
    Published
    DOI:
    10.3892/br.2021.1430 - link to the publication
  3. Could BMPs Therapy Be Improved if BMPs Were Used in Composition Acting during Bone Formation in Endochondral Ossification?
    Authors:
    Hyc A, Osiecka-Iwan A, Moskalewski S.
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23(18), strony: 10327), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms231810327.PMID: - link to the publication
  4. From Matrix Vesicles to Miniature Rocks: Evolution of Calcium Deposits in Calf Costochondral Junctions
    Authors:
    Jakub Jaroszewicz1 , Piotr Bazarnik1, Anna Osiecka-Iwan2, Anna Hyc2, Emilia Choinska1, Adrian Chlanda1 , Wojciech Swieszkowski1, and Stanisław Moskalewski2
    Academic press:
    artilage (rok: 2020, tom: on line, strony: 45301), Wydawca: Sage
    Status:
    Published
    DOI:
    10.1177/194760352094122 - link to the publication
  5. Growth factors in the initial stage of bone formation, analysis of their expression in chondrocytes from epiphyseal cartilage of rat costochondral junction
    Authors:
    A. Hyc, S. Moskalewski, A. Iwan
    Academic press:
    Folia Histochemica et Cytobiologica (rok: 2021, tom: 59, strony: 178-186), Wydawca: Via Medica
    Status:
    Published
    DOI:
    10.5603/FHC.a2021.0017. - link to the publication
  6. Toward osteomimetic formation of calcium phosphate coatings with carbonated hydroxyapatite.
    Authors:
    Joanna Idaszek, Jakub Jaroszewicz, Emilia Choińska, Żaneta Górecka, Anna Hyc, Anna Osiecka-Iwan, Barbara Wielunska-Kuś, Wojciech Święszkowski, StanisławMoskalewski.
    Academic press:
    Biomaterials Advances formerly known as Materials Science and Engineering: C (rok: 2023, tom: 149, strony: 213403 on line), Wydawca: ELsevier
    Status:
    Published
    DOI:
    10.1016/j.bioadv.2023.213403 - link to the publication