Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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A search for unique dual-action antibacterial agents

2016/21/N/NZ7/03464

Keywords:

quinolones antibacterial agents synthesis

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Joanna Fedorowicz 

Number of co-investigators in the project: 3

Call: PRELUDIUM 11 - announced on 2016-03-15

Amount awarded: 98 640 PLN

Project start date (Y-m-d): 2017-03-20

Project end date (Y-m-d): 2019-03-19

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Wyparka rotacyjna (12 000 PLN)
  2. Sprzęt komputerowy (4 800 PLN)
  3. Waga analityczna.

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (1)
  1. Lipophilicity Determination of Quaternary (Fluoro)Quinolones by Chromatographic and Theoretical Approaches
    Authors:
    Krzesimir Ciura, Joanna Fedorowicz, Filip Andrić, Katarzyna Ewa Greber, Alina Gurgielewicz, Wiesław Sawicki, Jarosław Sączewski
    Academic press:
    International Journal of Molecular Sciences (rok: 2019, tom: 20, strony: 5288), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms20215288 - link to the publication
  2. Modifications of quinolones and fluoroquinolones: hybrid compounds and dual-action molecules
    Authors:
    Joanna Fedorowicz, Jarosław Sączewski
    Academic press:
    Monatshefte für Chemie - Chemical Monthly (rok: 2018, tom: 149, strony: 1199-1245), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00706-018-2215-x - link to the publication
  3. Synthesis and biological evaluation of hybrid quinolone-based quaternary ammonium antibacterial agents
    Authors:
    Joanna Fedorowicz, Jarosław Sączewski, Agnieszka Konopacka, Krzysztof Waleron, Dawid Lejnowski, Krzesimir Ciura, Tihomir Tomašič, Žiga Skok, Kirsi Savijoki, Małgorzata Morawska, Shella Gilbert-Girard, Adyary Fallarero
    Academic press:
    European Journal of Medicinal Chemistry (rok: 2019, tom: 179, strony: 576-590), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ejmech.2019.06.071 - link to the publication
  1. A SEARCH FOR UNIQUE DUAL-ACTION ANTIBACTERIAL AGENTS
    Authors:
    Joanna Fedorowicz, Jarosław Sączewski, Agnieszka Konopacka, Krzysztof Waleron, Dawid Lejnowski
    Conference:
    VII EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry (rok: 2017, ), Wydawca: The European Federation for Medicinal Chemistry (EFMC)
    Data:
    konferencja August 27-31
    Status:
    Published

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