New, innovative hybrid materials useful in regenerative medicine based soley on natural components

2015/19/B/ST8/02594

Keywords

Descriptors

  • ST5_11: Synteza biomateriałów
  • NZ1_8: Inżynieria tkankowa
  • ST8_8: Inżynieria materiałowa (biomateriały, metale, ceramika, polimery, kompozyty)

Panel

ST8 – Production and processes engineering: modelling, product design, process design and control, construction methods and engineering, power units and systems

Host institution

Politechnika Łódzka, Wydział Chemiczny

Voivodeship: łódzkie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Beata Kolesińska

Number of co-investigators in the project: 23

Call

OPUS 10 – announced on 2015-09-15

Amount awarded
1 321 200 PLN
Project start date
2016-11-04
Project end date
2019-11-03
Project duration
36 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Automatyczny licznik komórek do oceny liczebności komórek, ich żywotności i rozmiarów. Cost: 30 000 PLN
  2. Spektrofotometr CD. Cost: 360 000 PLN

Information in the final report

Publication in academic press/journals (10)

  1. Insulin Hot‐Spot Analogs Formed with N‐Methylated Amino Acid Residues Inhibit Aggregation of Native Hormone

    Authors:
    Monika Swiontek, Joanna Wasko, Justyna Fraczyk, Krystian Galecki, Zbigniew J. Kaminski, Beata Kolesinska
    Academic press:
    Molecules (year: 2019, volume: 24, pages: 3706), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules24203706 – link to the publication
  2. Study on the Materials Formed by Self-Assembling Hydrophobic, Aromatic Peptides Dedicated to Be Used for Regenerative Medicine

    Authors:
    Chaberska A., Fraczyk J., Wasko J., Rosiak P., Kaminski Z.J., Solecka A., Stodolak-Zych E., Strzempek W., Menaszek E., Dudek M., Niemiec W., Kolesinska B.
    Academic press:
    Chem. Biodiversity (year: 2019, volume: 16, pages: e1800543), Publisher: Wiley-VHCA AG, Zurich, Switzerland
    Status:
    Published
    DOI:
    10.1002/cbdv.201800543 – link to the publication
  3. Search for Fibrous Aggregates Potentially Useful in Regenerative Medicine Formed under Physiological Conditions by Self-Assembling Short Peptides Containing Two Identical Aromatic Amino Acid Residues

    Authors:
    Justyna Fraczyk, Wojciech Lipinski, Agata Chaberska, Joanna Wasko, Kamil Rozniakowski, Zbigniew J. Kamiński, Maciej Bogun, Zbigniew Draczynski, Elzbieta Menaszek, Ewa Stodolak-Zych, Marta Kamińska, Beata Kolesinska
    Academic press:
    Molecules (year: 2018, volume: 23, pages: 568), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules23030568 – link to the publication
  4. Search for new hot spots responsible for the aggregation of human insulin

    Authors:
    Swiontek M., a Fraczyk J., Wasko J., Chaberska A., Pietrzak L., Kaminski Z.J., Szymanski L., Wiak S., Kolesinska B.,
    Academic press:
    Molecules (year: 2019, volume: 24, pages: 1600), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules24081600 – link to the publication
  5. Rusztowania (scaffolds) stosowane w medycynie regeneracyjnej

    Authors:
    Agata Chaberska, Piotr Rosiak, Zbigniew J. Kamiński, Beata Kolesińska
    Academic press:
    Wiadomości Chemiczne (year: 2017, volume: 71 (304), pages: 263-286), Publisher: Polskie Towarzystwo Chemiczne
    Status:
    Published
  6. Synthetic Extracellular Matrix as a Substrate for Regenerative Medicine

    Authors:
    Ewa Stodolak-Zych, Elzbieta Menaszek, Aleskandra Twardy, Anna Scisłowska-Czarnecka, Maciej Bogun, Beata Kolesinska
    Academic press:
    Engineering of Biomaterials (year: 2019, volume: 152, pages: 46310), Publisher: Czasopismo Polskiego Stowarzyszenia Biomateriałów i Wydziału Inżynierii Materiałowej i Ceramiki Akademii Górniczo-Hutniczej im. St. Staszica w Krakowie
    Status:
    Published
  7. New Human Islet Amyloid Polypeptide Fragments Susceptible to Aggregation

    Authors:
    Kamil Rozniakowski, Andrzej Fraczyk, Krystian Galecki, Joanna Wietrzyk, Beata Filip-Psurska, Justyna Fraczyk, Zbigniew J. Kaminski, Beata Kolesinska
    Academic press:
    Chem. Biodiversity (year: 2020, volume: 17, pages: e2000501), Publisher: Wiley
    Status:
    Published
    DOI:
    10.1002/cbdv.202000501 – link to the publication
  8. Fibrous Aggregates of Short Peptides Containing Two Distinct Aromatic Amino Acid Residues

    Authors:
    Wojciech Lipinski, Joanna Wasko, Malgorzata Walczak, Justyna Fraczyk, Zbigniew J. Kaminski, Krystian Galecki, Zbigniew Draczynski, Izabella Krucinska, Marta Kaminska, Beata Kolesinska
    Academic press:
    Chem. Biodiversity (year: 2019, volume: 16, pages: e1900339), Publisher: Wiley-VHCA AG, Zurich, Switzerland
    Status:
    Published
    DOI:
    10.1002/cbdv.201900339 – link to the publication
  9. Conjugates of Copper Alginate with Arginine-Glycine-Aspartic Acid (RGD) for Potential Use in Regenerative Medicine

    Authors:
    Justyna Fraczyk, Joanna Wasko, Malgorzata Walczak, Zbigniew J. Kaminski , Dorota Puchowicz, Irena Kaminska, Maciej Bogun, Marcin Kolasa, Ewa Stodolak-Zych, Anna Scislowska-Czarnecka, Beata Kolesinska
    Academic press:
    Materials (year: 2020, volume: 13, pages: 337), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ma13020337 – link to the publication
  10. Modification of chitosan fibers with short peptides as a model of synthetic extracellular matrix

    Authors:
    Ewa Stodolak-Zych, Piotr Jelen, Ewa Dzierzkowska, Małgorzata Krok-Borkowicz, Łukasz Zych, Maciej Bogun, Alicja Rapacz-Kmita, Beata Kolesinska
    Academic press:
    Journal of Molecular Structure (year: 2020, volume: 1211, pages: 128061), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.molstruc.2020.128061 – link to the publication

Articles in post-conference publications (27)

  1. POSZUKIWANIE AKTYWNYCH BIOLOGICZNIE FRAGMENTÓW BIAŁEK MACIERZY POZAKOMÓRKOWEJ UŻYTECZYCH W MEDYCYNIE REGENRACYJNEJ

    Authors:
    Kolesińska B., Frączyk J., Kamiński Z.J., Rosiak P., Becht A., Czerchawy A., Kozłowski F., Chaberska A., Waśko J., Czerczak K., Walczak M.,
    Conference:
    XI Multidyscyplinarna Konferencja Nauki o Leku (year: 2018, pages: 83, P10), Publisher: Instytut Farmaceutyczny
    Date:
    conference 14-16.XI. 2018
    Status:
    Published
  2. Self-organized nonamer and hexamer peptides as components of potential scaffolds for regenerative medicine

    Authors:
    Menaszek E. Strzempek W. Stodolak-Zych E. Bogun M. Kolesinska B.,
    Conference:
    2018 TERMIS World Congress The theme for the 2018 TERMIS World Congress is Integration of Industry, Government, and Academia for Regenerative Medicine, (year: 2018, pages: 220, 01_P555), Publisher: Kyoto International Conference Center, 2018 TERMIS World Congress http://www2.convention.co.jp/termis-wc2018/pdf/s_poster1.pdf
    Date:
    conference 4-7.IX. 2018
    Status:
    Published
  3. Poszukiwanie fragmentów białek użytecznych w medycynie regeneracyjnej

    Authors:
    Czerchawy, A., Kozłowski, F., Czerczak, K., Kamiński, Z.J., Kolesińska, B.
    Conference:
    XVII Ogólnopolskie Seminarium dla Doktorantów i Studentów Na pograniczu chemii i biologii 12 -15 maja 2019 r., Jastrzębia Góra, (year: 2019, pages: ISBN 978-83-951163-1-5, p 22), Publisher: -
    Date:
    conference 12 -15 maja 2019
    Status:
    Published
  4. Biologicznie aktywne fragmenty kolagenów użyteczne w medycynie regeneracyjnej

    Authors:
    Becht, A., Rosiak, P., Waśko, J., Kamiński, Z.J., Kolesińska, B.
    Conference:
    XVII Ogólnopolskie Seminarium dla Doktorantów i Studentów Na pograniczu chemii i biologii 12 -15 maja 2019 r., Jastrzębia Góra (year: 2019, pages: ISBN 978-83-951163-1-5, p 20), Publisher: -
    Date:
    conference 12 -15 maja 2019 r
    Status:
    Published
  5. Extracellular matrix model obtaining by electrospinning process

    Authors:
    Stodolak-Zych E., Kolesińska B., Zych Ł., Gargas M., Kołaczkowska E., Scisłowska-Czarnecka A.,
    Conference:
    Polish-Israeli Conference on Electrospinning and Tissue Engineering (year: 2018, pages: 30), Publisher: PICETE 2018, Institute of Fundamental Technological Research, Polish Academy of Sciences
    Date:
    conference 4-5.X.2018
    Status:
    Published
  6. Extracellular Matrix Substitute with Natural Polysaccharides and Small Peptide

    Authors:
    Stodolak-Zych E., Solecka A., Golańska J., Niemiec W., Boguń M., Draczyński Z., Kolesińska B.,
    Conference:
    4th International Conference on Biomedical Polymers and Polymeric Biomaterials (year: 2018, pages: ISBPPB2018, 191), Publisher: Polish Society for Biomaterials in Krakow
    Date:
    conference 15-18.VII.2018
    Status:
    Published
  7. Searching for biologically active fragments of growth factors

    Authors:
    Czerczak, K., Frączyk, J., Kamiński, Z.J., Kolesińska, B.
    Conference:
    25th Polish Peptide Symposium, Wojanów, 8-12.09.2019 (year: 2019, pages: P7, p71, ISBN: 978-83-63377-44-1), Publisher: -
    Date:
    conference 8-12.09.2019
    Status:
    Published
  8. Selection of Active fragments of collagen

    Authors:
    Kolesińska B., Frączyk J., Kamiński Z., Rosiak P., Becht A., Czerchawy A., Chaberska A., Waśko J., Czerczak K., Walczak M.,
    Conference:
    27th Biomaterials in Medicine and Veterinary Medicine, Annual Conference (year: 2018, pages: 41), Publisher: Polish Society for Biomaterials in Krakow
    Date:
    conference 11-14.X.2018
    Status:
    Published
  9. Hydrofobowe peptydy jako układy samoorganizujące się

    Authors:
    Chaberska A., Rosiak P., Frączyk J., Kamiński Z., Dudek M., Kamińska M., Kolesińska B.,
    Conference:
    61 Zjazd Naukowy Polskiego Towarzystwa Chemicznego (year: 2018, pages: S012P56, S02-37), Publisher: Polskie Towarzystwo Chemiczne
    Date:
    conference 17-21.IX.2018
    Status:
    Published
  10. FIBROUS STRUCTURES BASED OF NATURAL POLYMERS FOR TISSUE ENGINEERING APPLICATIONS

    Authors:
    Stodolak-Zych E., Ścisłowska-Czarnecka A., Kolesińska B., Cieślak M., Puchowicz D., Kamińska I., Boguń M.,
    Conference:
    27th Biomaterials in Medicine and Veterinary Medicine, Annual Conference (year: 2018, pages: 63), Publisher: Polish Society for Biomaterials in Krakow
    Date:
    conference 11-14.X.2018
    Status:
    Published
  11. Modification of chitosan surface with short peptides as a model of synthetic extracellular matrix

    Authors:
    P. JELEŃ, E. DZIERZKOWSKA, Ł. ZYCH, M. Bogun, B. Kolesińska, E. STODOLAK-ZYCH
    Conference:
    XV-th International conference on Molecular spectroscopy: from molecules to molecular materials, biological molecular systems and nanostructures: 15–19.9.2019, Wrocław–Wojanów Poland. (year: 2019, pages: P29, 101), Publisher: -
    Date:
    conference 15–19.9.2019
    Status:
    Published
  12. Poszukiwanie biologicznie aktywnych fragmentów kolagenów użytecznych w medycynie regeneracyjnej

    Authors:
    Becht A., Rosiak P., Chaberska A., Waśko J., Frączyk J., Kamiński Z., Kolesińska B.,
    Conference:
    61 Zjazd Naukowy Polskiego Towarzystwa Chemicznego (year: 2018, pages: S012P55, S02-37), Publisher: Polskie Towarzystwo Chemiczne
    Date:
    conference 17-21.IX.2018
    Status:
    Published
  13. Effect of carbon nanofibers surface modification with biomolecules on structural properties and cellular response

    Authors:
    Ewa DZIERZKOWSKA, Elżbieta Menaszek, Marek NOCUŃ, Beata Kolesińska, Ewa STODOLAK-ZYCH
    Conference:
    EUPOC 2019 Electrospinning and related techniques: From design to production of advanced polymer materials and devices : 12-16 May 2019, Como, Italy (year: 2019, pages: Book of Abstracts, OC19, p. 31), Publisher: -
    Date:
    conference 12-16 May 2019
    Status:
    Published
  14. Peptides supporting the reconstruction of extracellular matrix (ECM) and the cytoskeleton components

    Authors:
    Kolesinska B.
    Conference:
    25th Polish Peptide Symposium, Wojanów, 8-12.09.2019 (year: 2019, pages: L34, p56, ISBN: 978-83-63377-44-1.), Publisher: -
    Date:
    conference 8-12.09.2019
    Status:
    Published
  15. Stability of synthetic extracellular matrices modified with collagen derivatives in in vitro conditions

    Authors:
    Ewa DZIERZKOWSKA, Agnieszka Solecka, Piotr SZATKOWSKI, Katarzyna NOWICKA, Beata Kolesińska, Maciej Boguń, Ewa STODOLAK-ZYCH
    Conference:
    SAT'2019: IX Szkoła Analizy Termicznej : 22–25 września 2019, Zakopane, Poland (year: 2019, pages: 31), Publisher: -
    Date:
    conference 22–25 września 2019
    Status:
    Published
  16. Influence of chitosan nonwoven fabric modification on its physicochemical and biological properties

    Authors:
    Ewa DZIERZKOWSKA, Anna Ścisłowska-Czarnecka, Beata Kolesińska, Maciej Boguń, Ewa STODOLAK-ZYCH
    Conference:
    28th annual conference Biomaterials in medicine and veterinary medicine Engineering of Biomaterials; ISSN 1429-7248. — 2019 vol. 22 no. 153 spec. iss., s. 103, 10-13 October 2019 Rytro, Poland. (year: 2019, pages: ISSN 1429-7248, 2019, 22(153 spec. iss.) s. 103), Publisher: -
    Date:
    conference 10-13 October 2019
    Status:
    Published
  17. Materials formed from biomolecules by self-aggregation process as a scaffolds useful in regenerative medicine

    Authors:
    Kolesinska, B.; Fraczyk, J.; Chaberska, A.; Rosiak, P.; Wasko, J.; Kaminski1, Z.J.; Draczynski, Z.; Bogun, M.; Zych-Stodolak, E.; Menaszek, E.
    Conference:
    4th International Conference on Nanotechnology in Medicine (NANOMED) (year: 2016, pages: MED-65), Publisher: NANOSMAT Society
    Date:
    conference 07-09 November 2016
    Status:
    Published
  18. Stable triazine based coupling reagents, scope and limitations of the utility

    Authors:
    Kolesińska, B.
    Conference:
    24th Polish Peptide Symposium, Jastrzębia Góra, 03 – 07 September, 2017 (year: 2017, pages: Materiały Zjazdu 34, OP11.), Publisher: CTT Innovation synergy, printed by Format XL
    Date:
    conference 03 – 07 September, 2017
    Status:
    Published
  19. Peptides containing aromatic amino acids as a scaffolds for regenerative medicine

    Authors:
    Chaberska, A., Rosiak P., Frączyk J., Lipiński W., Kamiński Z., Kolesińska B.
    Conference:
    24th Polish Peptide Symposium, Jastrzębia Góra, 03 – 07 September, 2017 (year: 2017, pages: Materiały Zjazdu 64, P8), Publisher: CTT Innovation Synergy, Printed by FormatXL
    Date:
    conference 03 – 07 September, 2017
    Status:
    Published
  20. Hybrid materials based on peptides and saccharides useful for regenerative medicine

    Authors:
    Fraczyk J, Becht A., Rosiak P., Chaberska A., Wasko J., Kaminski Z.J., Draczynski Z., Krucinska I., Kaminska M., Kolesinska B.,
    Conference:
    5TH NANOMED & 11TH ITMED 2018, Manchester, UK, 26-28.VI.2018 (year: 2018, pages: Book of Abstracts, ITM-3 (INV), p 33-34.), Publisher: NanoMed
    Date:
    conference Manchester, UK, 26-28.VI.2018
    Status:
    Published
  21. Monitoring of the hydrolytic and enzymatic degradation process of fibrous polysaccharides-protein scaffolds

    Authors:
    Stodolak-Zych E., Gajek M., Rapacz-Kmita A., Zych Ł., Kolesińska B.,
    Conference:
    13th Conference on Calorimetry and Thermal Analysis of the Polish Society of Calorimetry and Thermal Analysis (year: 2018, pages: S10_P3, 219), Publisher: Polish Society of Calorimetry and Thermal Analysis
    Date:
    conference Zakopane, Poland, 2-6.IX.2018
    Status:
    Published
  22. FRAGMENTY KOLAGENU JAKO UKŁADY ZDOLNE MIMIKOWAĆ FUNKCJE NATURALNEGO BIAŁKA MACIERZY POZAKOMÓRKOWEJ

    Authors:
    Szczęśniak I., Becht A., Rosiak P., Chaberska A., Waśko J., Walczak M., Frączyk J., Kamiński Z.J., Kolesińska B.
    Conference:
    60 Zjazd Naukowy Polskiego Towarzystwa Chemicznego (year: 2017, pages: S01P139, 687), Publisher: Polskie Towarzystwo Chemiczne
    Date:
    conference 17-21 września 2017
    Status:
    Published
  23. Application of highly ordered peptides for manufacturing of smart biocompatible materials

    Authors:
    Kolesinska B., Fraczyk J., Chaberska A., Lipinski W., Wasko J., Kaminski Z.J., Draczynski Z., Bogun M., Zych-Stodolak E., Menaszek E., Mitura K.
    Conference:
    3rd International Conference on Surface, Coatings and Nanostructured Materials – ASIA, Hong Kong (year: 2017, pages: Nano-56, Book of Abstract, p 29), Publisher: Nanosmat Society
    Date:
    conference 4-7 December 2017
    Status:
    Published
  24. Peptides as Components of Potential Scaffolds for Regenerative Medicine

    Authors:
    Strzempek W., Menaszek, E., Dziadek, M., Stodolak-Zych E., Boguń M., Kolesińska B.
    Conference:
    26th Biomaterials in Medicine and Veterinary Medicine, Engineering of Biomaterials (year: 2017, pages: Engineering of Biomaterials, 143, 2017, page 74), Publisher: Engineerings of Biomaterials
    Date:
    conference 12-15 October, 2017 Rytro
    Status:
    Published
  25. Structure and Properies of Biomimetic ECM Like Scaffolds in In Vitro Conditio

    Authors:
    Stodolak-Zych E., Boguń M., Draczyński Z., Kolesinska B.,
    Conference:
    XIVth International Conference on Molecular Spectroscopy, Kraków, Białka Tatrzańska, 3-7 September 2017 (year: 2017, pages: TP:2 P-39, page 254.), Publisher: ICMS, AGH
    Date:
    conference 3-7 September 2017
    Status:
    Published
  26. SAMOORGANIZUJĄCE SIĘ ZWIĄZKI NATURALNE W MEDYCYNIE REGENERACYJNEJ

    Authors:
    Kolesińska B., Frączyk J., Chaberska A., Waśko J., Lipiński W., Kamiński Z.J., Boguń M., Draczyński Z., Menaszek E., Stodolak-Zych E.
    Conference:
    60 Zjazd Naukowy Polskiego Towarzystwa Chemicznego (year: 2017, pages: S01K23, 300), Publisher: Polskie Towarzystwo Chemiczne
    Date:
    conference 17-21 września 2017
    Status:
    Published
  27. FRAGMENTY KOLAGENU I UŻYTECZNE W MEDYCYNIE REGENERACYJNEJ

    Authors:
    Becht A., Walczak M., Chaberska A., Waśko J., Frączyk J., Kamiński Z.J., Kolesińska B.
    Conference:
    60 Zjazd Naukowy Polskiego Towarzystwa Chemicznego (year: 2017, pages: S01P06, 554), Publisher: Polskie Towarzystwo Chemiczne
    Date:
    conference 17-21 września 2017
    Status:
    Published

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Graphic design and implementation: Jakub Piotrowski